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Microbiome: Its Impact Is Being Revealed!

  • Mycology (J Perfect, Section Editor)
  • Published:
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Abstract

Purpose of Review

Thriving microbiome research for the past few years is providing new insights into biological mechanisms guiding human health and/or disease states. In this review, we will highlight the recent literature providing further evidence for the central role that the microbiota plays in association with the human host.

Recent Findings

The host microbiota, both bacteria and fungi, with their collective genome (metagenome) and metabolites (metabolome) play a key role in health and disease states. We now have enough evidence that there are strong relationships and multidirectional interactions between the human host and the commensal bacterial, fungal, and viral inhabitants.

Summary

Microbiome research has been at the forefront of research as a potential future target for precision medicine with the development of novel diagnostic assays and treatment approaches. Ongoing investigations are still unraveling the mechanisms by which such organisms contribute to health and disease.

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References

Papers of particular interest, published recently, have been highlighted as: •• Of major importance

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Authors and Affiliations

  1. Department of Medicine, Division of Hematology-Oncology, Case Western Reserve University and University Hospitals Cleveland Medical Center, Cleveland, OH, USA

    Najla El-Jurdi, Marcos de Lima & Hillard Lazarus

  2. Department of Dermatology, Center of Medical Mycology, Case Western Reserve University and University Hospitals Cleveland Medical Center, 11106 Euclid Avenue, Cleveland, OH, 44106, USA

    Mahmoud A. Ghannoum

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  1. Najla El-Jurdi
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  2. Marcos de Lima
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  4. Mahmoud A. Ghannoum
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Correspondence to Mahmoud A. Ghannoum.

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El-Jurdi, N., de Lima, M., Lazarus, H. et al. Microbiome: Its Impact Is Being Revealed!. Curr Clin Micro Rpt 4, 78–87 (2017). https://doi.org/10.1007/s40588-017-0063-9

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