Abstract
Background and aim
Disability is an important health problem among older individuals, prompting the need for long-term care. Age-related disability is usually associated with mobility; however, little is known about the association between mobility and long-term care. Therefore, this study aimed to clarify the association between the timed up and go (TUG) test measuring mobility and long-term care eligibility.
Patients and methods
We analyzed follow-up data of 489 community-dwelling healthy older adults (≥ 65 years) who participated in a prospective observational study. They were divided into certified (59 participants) and uncertified (430 participants) groups based on long-term care eligibility. Anthropometric and physical functioning measures included the TUG test and hand grip strength (HGS), among others. These measures were compared between groups and a multivariate logistic regression analysis evaluated the association between the TUG test times and long-term care eligibility.
Results
Participants’ minimum follow-up period was 4 years. TUG times were significantly slower (median time: 7.4 vs. 8.3 s, p < 0.001) and HGS and knee-extension strength significantly lower in the certified group than in the uncertified group. The logistic regression analysis showed that TUG times were significantly associated with long-term care eligibility after adjusting for potential covariates. In addition, mediation analysis showed that 53.1% of the association between HGS and long-term care eligibility was mediated through TUG times.
Conclusion
The TUG test was associated with long-term care eligibility among healthy older adults, implying that the test may be helpful as a predictor for the early determination of dependence in old age.
Similar content being viewed by others
References
Guralnik JM, Alecxih L, Branch LG et al (2002) Medical and long-term care costs when older persons become more dependent. Am J Public Health 92:1244–1245. https://doi.org/10.2105/AJPH.92.8.1244
Ministry of Health, Labour and Welfare (2007) Overview of the revision of the long-term care insurance system. http://www.ilcjapan.org/linksE/doc/Overview_of_the_Revision_of_LTCI.pdf. Accessed 25 Aug 2017
Tsutsui T, Muramatsu N (2005) Care-needs certification in the long-term care insurance system of Japan. J Am Geriatr Soc 53:522–527. https://doi.org/10.2105/AJPH.92.8.1244
Ministry of Health, Labour and Welfare (2013) Comprehensive survey of living conditions. https://www.mhlw.go.jp/english/database/db-hss/cslc-tables.html. Accessed 25 Aug 2017
Marzetti E, Hwang A-C, Tosato M et al (2018) Age-related changes of skeletal muscle mass and strength among Italian and Taiwanese older people: results from the Milan EXPO 2015 survey and the I-Lan longitudinal aging study. Exp Gerontol 102:76–80. https://doi.org/10.1016/j.exger.2017.12.008
Li H, Lv C, Zhang T et al (2014) Trajectories of age-related cognitive decline and potential associated factors of cognitive function in senior citizens of Beijing. Curr Alzheimer Res 11:806–816. https://doi.org/10.2174/156720501108140910123112
Wennie HWN, Perera S, VanSwearingen J et al (2010) Performance measures predict onset of activity of daily living difficulty in community-dwelling older adults. J Am Geriatr Soc 58:844–852. https://doi.org/10.1111/j.1532-5415.2010.02820.x
Guralnik JM, Simonsick EM, Ferrucci L et al (1994) A short physical performance battery assessing lower extremity function: association with self-reported disability and prediction of mortality and nursing home admission. J Gerontol 49:M85–M94. https://doi.org/10.1093/geronj/49.2.M85
Podsiadlo D, Richardson S (1991) The timed “up & go”: a test of basic functional mobility for frail elderly persons. J Am Geriatr Soc 39:142–148. https://doi.org/10.1111/j.1532-5415.1991.tb01616.x
Benavent-Caballer V, Sendin-Magdalena A, Lisón JF et al (2016) Physical factors underlying the timed “up and go” test in older adults. Geriatr Nurs 37:122–127. https://doi.org/10.1016/j.gerinurse.2015.11.002
Alonso AC, Ribeiro SM, Luna NMS et al (2018) Association between handgrip strength, balance, and knee flexion/extension strength in older adults. PLoS One 13:e0198185. https://doi.org/10.1371/journal.pone.0198185
Riebe D, Blissmer BJ, Greaney ML et al (2009) The relationship between obesity, physical activity, and physical function in older adults. J Aging Health 21:1159–1178. https://doi.org/10.1177/0898264309350076
Shumway-Cook A, Brauer S, Woollacott M (2000) Predicting the probability for falls in community-dwelling older adults using the timed up & go test. Phys Ther 80:896–903
Beauchet O, Fantino B, Allali G et al (2011) Timed up and go test and risk of falls in older adults: a systematic review. J Nutr Health Aging 15:933–938. https://doi.org/10.1007/s12603-011-0062-0
Ohtake M, Morikagi Y, Suzuki I et al (2013) Effects of exercise on the prevention of conditions leading to the need for long-term care. Aging Clin Exp Res 25:49–57. https://doi.org/10.1007/s40520-013-0016-y
Yamada M, Arai H, Sonoda T et al (2012) Community-based exercise program is cost-effective by preventing care and disability in Japanese frail older adults. J Am Med Dir Assoc 13:507–511. https://doi.org/10.1016/j.jamda.2012.04.001
Otsuka H, Yanai M, Kobayashi H et al (2018) High-molecular-weight adiponectin levels in healthy, community-dwelling, elderly Japanese volunteers: a 5-year prospective observational study. Aging Clin Exp Res 30:791–798. https://doi.org/10.1007/s40520-017-0840-6
Imai K, Keele L, Tingley D et al (2011) Unpacking the black box of causality: learning about causal mechanisms from experimental and observational studies. Am Polit Sci Rev 105:765–789. https://doi.org/10.1017/S0003055411000414
Valeri L, Vanderweele TJ (2013) Mediation analysis allowing for exposure-mediator interactions and causal interpretation: theoretical assumptions and implementation with SAS and SPSS macros. Psychol Methods 18:137–150. https://doi.org/10.1037/a0031034
Kamiya K, Adachi T, Sasou K et al (2017) Risk factors for disability progression among Japanese long-term care service users: a 3-year prospective cohort study. Geriatr Gerontol Int 17:568–574. https://doi.org/10.1111/ggi.12756
Kamiya K, Sasou K, Fujita M et al (2013) Predictors for increasing eligibility level among home help service users in the Japanese long-term care insurance system. Biomed Res Int 2013:374130. https://doi.org/10.1155/2013/374130
Akune T, Muraki S, Oka H et al (2014) Incidence of certified need of care in the long-term care insurance system and its risk factors in the elderly of Japanese population-based cohorts: the ROAD study. Geriatr Gerontol Int 14:695–701. https://doi.org/10.1111/ggi.12155
Ikemoto T, Inoue M, Nakata M et al (2016) Locomotive syndrome is associated not only with physical capacity but also degree of depression. J Orthop Sci 21:361–365. https://doi.org/10.1016/j.jos.2016.01.003
Cruz-Jentoft AJ, Baeyens JP, Bauer JM et al (2010) Sarcopenia: European consensus on definition and diagnosis: report of the European Working Group on Sarcopenia in Older People. Age Ageing 39:412–423. https://doi.org/10.1093/ageing/afq034
Fried LP, Tangen CM, Walston J et al (2001) Frailty in older adults: evidence for a phenotype. J Gerontol A Biol Scie Med Sci 56:M146–M157. https://doi.org/10.1093/gerona/56.3.M146
Bischoff HA, Stahelin HB, Monsch AU et al (2003) Identifying a cut-off point for normal mobility: a comparison of the timed ‘up and go’ test in community-dwelling and institutionalised elderly women. Age Ageing 32:315–320. https://doi.org/10.1093/ageing/32.3.315
Kojima G, Masud T, Kendrick D et al (2015) Does the timed up and go test predict future falls among British community-dwelling older people? Prospective cohort study nested within a randomised controlled trial. BMC Geriatr 15:38. https://doi.org/10.1186/s12877-015-0039-7
Tomita Y, Arima K, Kanagae M et al (2015) Association of physical performance and pain with fear of falling among community-dwelling Japanese women aged 65 years and older. Medicine 94:e1449. https://doi.org/10.1097/MD.0000000000001449
Kamide N, Takahashi K, Shiba Y (2011) Reference values for the Timed Up and Go test in healthy Japanese elderly people: determination using the methodology of meta-analysis. Geriatr Gerontol Int 11:445–451. https://doi.org/10.1111/j.1447-0594.2011.00704.x
Yoshimura N, Oka H, Muraki S et al (2011) Reference values for hand grip strength, muscle mass, walking time, and one-leg standing time as indices for locomotive syndrome and associated disability: the second survey of the ROAD study. J Orthop Sci 16:768–777. https://doi.org/10.1007/s00776-011-0160-1
Robert HC, Syddall HE, Sparkes J et al (2014) Grip strength and its determinants among older people in different healthcare settings. Age Ageing 43:241–246. https://doi.org/10.1093/ageing/aft118
Stevens PJ, Syddall HE, Patel HP et al (2012) Is grip strength a good marker of physical performance among community-dwelling older people? J Nutr Health Aging 16:769–774. https://doi.org/10.1007/s12603-012-0388-2
Rantanen T (2003) Muscle strength, disability and mortality. Scand J Med Sci Sports 13:3–8. https://doi.org/10.1034/j.1600-0838.2003.00298.x
Tinetti ME, Inouye SK, Gill TM et al (1995) Shared risk factors for falls, incontinence, and functional dependence: Unifying the approach to geriatric syndromes. JAMA 273:1348–1353. https://doi.org/10.1001/jama.1995.03520410042024
Acknowledgements
This study was partially supported by a grant from the “Strategic Research Base Development” Program for Private Universities, subsidized by the Ministry of Education, Culture, Sports, Science and Technology (MEXT) in Japan (2011), as well as a generous donation from the Saitama Prefecture University.
Author information
Authors and Affiliations
Corresponding author
Ethics declarations
Conflict of interest
The authors report no conflicts of interest.
Statement of human rights
Approval for the present study was obtained from the Research Committee of Nihon University School of Medicine, Tokyo, Japan. This study was conducted in accordance with the principles of the Declaration of Helsinki.
Informed consent
All participants provided written informed consent to participate at their first visit.
Additional information
Publisher's Note
Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.
Rights and permissions
About this article
Cite this article
Otsuka, H., Kobayashi, H., Suzuki, K. et al. Mobility performance among healthy older adults eligible for long-term care in Japan: a prospective observational study. Aging Clin Exp Res 32, 1931–1937 (2020). https://doi.org/10.1007/s40520-019-01404-2
Received:
Accepted:
Published:
Issue Date:
DOI: https://doi.org/10.1007/s40520-019-01404-2