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Optimization of geometric indicators of a ventricular pump using computational fluid dynamics, surrogate model, response surface approximation, kriging and particle swarm optimization algorithm

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Abstract

A ventricular pump is a device used to treat patients with heart failure. In this device, the blood pressure is very important. On the other hand, the power use and efficiency are very important due to the battery volume reduction. In this study, it was attempted to introduce an optimum example of this pump using computational fluid dynamics (CFD) as an accurate method along with kriging and surrogate meta-models to reduce time and particle swarm optimization (PSO) algorithm. 5 indicators have been investigated as geometric optimization indicators in this study. Blade inlet angle, blade outlet angle, number of blades, the distance from the leading edge of the blade to the inlet eye of the pump and finally the width of the blade (viewed from the side to the blade) are the geometrical indicators analyzed in this study for their effects on the optimization. In this study, the power, efficiency, head, hemolysis and relative hemolysis have been analyzed, and hemolysis and efficiency have been introduced as the main objectives of PSO and pump head has been considered as a constraint. The introduced optimum example has reduced hemolysis more than 9% and power use more than 10% compared to the model investigated by the American Food and Drug Administration, while the efficiency has also increased by more than 2% and the related constraint to the pump head is maintained.

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Abbreviations

a 0 :

Coefficients of the polynomial

a i :

Coefficients of the polynomial

a ii :

Coefficients of the polynomial

a ij :

Coefficients of the polynomial

C :

Constant fit the hemolysis data

f(x):

Polynomial function in kriging model

Hb :

Blood hemoglobin concentration

HI :

Hemolysis index

N d :

Number of design variables

P i :

Optimal point

R :

Pipe radius

r:

Radial direction

t exp :

The exposure time of blood cells in the device

V :

Velocity

x i :

Values of design variables in the RSA model

X i :

Location of the particle

Z :

Axial direction

Z(x):

Localized deviations function in the kriging model

α :

Constant fit the hemolysis data

β :

Cotant fit the hemolysis data

\(\tau_{s}\) :

The magnitude of scalar shear stress

ν:

The velocity of blood

\(v_{i}\) :

Speed of the particle

References

  1. Stanford Health Care (2022). https://stanfordhealthcare.org/medical-treatments/l/lvad.html.

  2. Xinwei SDO, Houston GW (2004) Computational fluid dynamics (CFD) study of the 4th generation prototype of a continuous flow ventricular assist device (VAD). ASME 126

  3. Faghih MM, Sharp MK (2016) Extending the power-law hemolysis model to complex flows. ASME J Biomech Eng 138:2016. https://doi.org/10.1115/1.4034786

    Article  Google Scholar 

  4. Bozzi ACLRS, Vesentini S, Santus M, Ghelli N, Fontanili P, Corbelli M, Fiore GB (2020) Fluid dynamics characterization and thrombogenicity assessment of a levitating centrifugal pump with different impeller designs. Med Eng Phys 5:26–33

    Article  Google Scholar 

  5. Song X, Throckmorton AL, Wood HG, Antaki JF, Olsen DB (2003) Computational fluid dynamics prediction of blood damage in a centrifugal pump. Artif Organs 27(10):938–941

    Article  Google Scholar 

  6. Arvand A, Hormes M, Reul H (2005) A validated computational fluid dynamics model to estimate hemolysis in a rotary blood pump. Artif Organs 29(7):531–540

    Article  Google Scholar 

  7. Zhang J et al (2006) Computational and experimental evaluation of the fluid dynamics and hemocompatibility of the CentriMag blood pump. Artif Organs 30(3):168–177

    Article  Google Scholar 

  8. Wu J, Paden BE, Borovetz HS, Antaki JF (2009) Computational fluid dynamics analysis of blade tip clearances on hemodynamic performance and blood damage in a centrifugal ventricular assist device. Artif Organs 7:402–411

    Article  Google Scholar 

  9. Taskin ME et al (2010) Computational characterization of flow and hemolytic performance of the ultramag blood pump for circulatory support. Artif Organs 34(12):1099–1113. https://doi.org/10.1111/j.1525-1594.2010.01017.x

    Article  Google Scholar 

  10. Fraser KH, Taskin ME, Griffith BP, Wu ZJ (2011) The use of computational fluid dynamics in the development of ventricular assist devices. Med Eng Phys 33(3):263–280. https://doi.org/10.1016/j.medengphy.2010.10.014

    Article  Google Scholar 

  11. Fraser ZH, Zhang K, Taskin T, Ertan M, Griffith P, Wu BJ (2012) A quantitative comparison of mechanical blood damage parameters in rotary ventricular assist devices: shear stress, exposure time and hemolysis index. ASME J Biomech Eng 134:247

    Article  Google Scholar 

  12. Taskin AZWME, Fraser KH, Zhang T, Wu C, Griffith BP (2012) Evaluation of eulerian and lagrangian models for hemolysis estimation. ASAIO J 58(4):363–372. https://doi.org/10.1097/MAT.0b013e318254833b

    Article  Google Scholar 

  13. Zhang BPGJ, Zhang P, Fraser KH, Wu ZJ (2013) Comparison and experimental validation of fluid dynamic numerical models for a clinical ventricular assist device. Artif Organs 37(4):380–389. https://doi.org/10.1111/j.1525-1594.2012.01576.x

    Article  Google Scholar 

  14. Hariharan P, Souza GD, Horner M, Malinauskas RA, Myers MR (2016) Verification benchmarks to assess the implementation of computational fluid dynamics based hemolysis prediction models. J Biomech Eng 137:1–10. https://doi.org/10.1115/1.4030823

    Article  Google Scholar 

  15. Kevin EB, Christopher C, Charles D, Daniel H, Onur D, Julien D, Kaitlyn S, Burke WK (2016) Design rationale and preclinical evaluation of the HeartMate 3 left ventricular assist system for hemocompatibility. ASAIO J 62(4):375–383. https://doi.org/10.1097/MAT.0000000000000388

    Article  Google Scholar 

  16. Jabbarifar M, Riasi A (2018) Numerical study on hemolysis induced by speed-changing heart pump (in persian). Modares Mech Eng 18(02):273–280

    Google Scholar 

  17. Malinauskas BA, Richard A, Prasanna H, Steven DW, Herbertson LH, Martin B, Ulrich S, Aycock KI, Good BC, Steven D, Manning KB (2017) FDA benchmark medical device flow models for CFD validation. ASAIO J 63(2):150–160. https://doi.org/10.1097/MAT.0000000000000499

    Article  Google Scholar 

  18. Wiegmann VKL, Thamsen B, de Diane Z, Marcus G, Stefan B, Marianne SD, Mirko M (2018) Fluid dynamics in the HeartMate 3: influence of the artificial pulse feature and residual cardiac pulsation. Artif Organs 43(4):363–376. https://doi.org/10.1111/aor.13346

    Article  Google Scholar 

  19. Sahebi-Kuzeh-Kanan K, Niroomand-Oscuii R, Yazdanpanah-Ardakani H (2020) Design and simulation of the right ventricular mini assist centrifugal pump (In Persian). Iran J Biomed Eng 13(4):315–326

    Google Scholar 

  20. Samad K-YA, Kim T, Goel TH, Raphael S. W (2008) Multiple surrogate modeling for axial compressor blade shape optimization. J Propuls POWER 2:96

    Google Scholar 

  21. Mojaddam M, Pullen KR (2019) Optimization of a centrifugal compressor using the design of experiment technique. Appl Sci (Switzerland). https://doi.org/10.3390/app9020291

    Article  Google Scholar 

  22. Pei J, Wang W, Osman MK, Gan X (2019) Multiparameter optimization for the nonlinear performance improvement of centrifugal pumps using a multilayer neural network. J Mech Sci Technol 33(6):2681–2691. https://doi.org/10.1007/s12206-019-0516-6

    Article  Google Scholar 

  23. Zhang J, Zhu H, Yang C, Li Y, Wei H (2011) Multi-objective shape optimization of helico-axial multiphase pump impeller based on NSGA-II and ANN. Energy Convers Manag 52(1):538–546. https://doi.org/10.1016/j.enconman.2010.07.029

    Article  Google Scholar 

  24. Wang JZW, Yuan S (2015) Optimization of the diffuser in a centrifugal pump by combining response surface method with multi-island genetic algorithm. Process Mech Eng 2:58

    Google Scholar 

  25. Pei J, Wang W, Yuan S (2016) Multi-point optimization on meridional shape of a centrifugal pump impeller for performance improvement. J Mech Sci Technol 30(11):4949–4960. https://doi.org/10.1007/s12206-016-1015-7

    Article  Google Scholar 

  26. Almasi S, Ghorani MM, Haghighi MHS, Mirghavami SM, Riasi A (2021) Optimization of a vacuum cleaner fan suction and shaft power using Kriging surrogate model and MIGA. Proc Inst Mech Eng Part A J Power Energy. https://doi.org/10.1177/09576509211049613

    Article  Google Scholar 

  27. Bellary SAI, Husain A, Samad A (2014) Effectiveness of meta-models for multi-objective optimization of centrifugal impeller. J Mech Sci Technol 28(12):4947–4957. https://doi.org/10.1007/s12206-014-1116-0

    Article  Google Scholar 

  28. Kennedy REJ (1995) Particle swarm optimisation. Stud Comput Intell 2:71. https://doi.org/10.1007/978-3-030-61111-8_2

    Article  Google Scholar 

  29. Gen RM (1999) Genetic algorithms and engineering optimization. Wiley, London

    Book  Google Scholar 

  30. Ghorani MM, Hadi M, Haghighi S, Riasi A (2020) Entropy generation minimization of a pump running in reverse mode based on surrogate models and NSGA-II. Int Commun Heat Mass Transf 118:104898. https://doi.org/10.1016/j.icheatmasstransfer.2020.104898

    Article  Google Scholar 

  31. Pei J, Wang W, Yuan S, Zhang J (2016) Optimization on the impeller of a low-specific-speed centrifugal pump for hydraulic performance improvement. Chin J Mech Eng 29(5):992–1002. https://doi.org/10.3901/CJME.2016.0519.069

    Article  Google Scholar 

  32. Ghadimi B, Nejat A, Nourbakhsh SA, Naderi N (2018) Shape optimization of a centrifugal blood pump by coupling CFD with metamodel-assisted genetic algorithm. J Artif Organs 2:17

    Google Scholar 

  33. Ghadimi B, Nejat A, Ahmad NS, Naderi N (2018) Multi objective genetic algorithm assisted by ANN metamodel for shape optimization of a centrifugal blood pump. Artif Organs 25:689

    Google Scholar 

  34. Zhang Y et al (2008) Design optimization of an axial blood pump with computational fluid dynamics YAN. ASAIO J 5:96

    Google Scholar 

  35. Zhu L, Zhang X, Yao Z (2010) Shape optimization of the diffuser blade of an axial blood pump by computational fluid dynamics. Artif Organs 34(3):185–192

    Article  Google Scholar 

  36. Yu DTH, Janiga G (2015) Computational fluid dynamics-based design optimization method for archimedes screw blood pumps Hai. Artif Organs 40(4):341–352

    Article  Google Scholar 

  37. Universio CB (1995) Three-dimensional numerical prediction of stress loading of blood particles in a centrifugal pump. Arrif Organ 2:96

    Google Scholar 

  38. National Cancer Institude (2022). https://ncihub.org/wiki/FDA_CFD/ComputationalRoundRobin2Pump

  39. Zhou Y-P, Tang L-JT, Jiao J, Song D-D, Jiang J-H, Yu R-Q (2009) Modified particle swarm optimization algorithm for adaptively configuring globally optimal classification and regression treespdf. J Chem Inf Model 2:79

    Google Scholar 

  40. Bashiri M, Derakhshan S, Shahrabi J (2019) Design optimization of a centrifugal pump using particle swarm optimization algorithm. Int J Fluid Mach Syst 12(4):322–331. https://doi.org/10.5293/IJFMS.2019.12.4.322

    Article  Google Scholar 

  41. Zhang Y, Wang S, Ji G (2015) A comprehensive survey on particle swarm optimization algorithm and its applications. Math Probl Eng 20:15. https://doi.org/10.1155/2015/931256

    Article  MathSciNet  Google Scholar 

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Correspondence to Amirhamzeh Farajollahi.

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Saleh-Abadi, M., Rahmati, A., Farajollahi, A. et al. Optimization of geometric indicators of a ventricular pump using computational fluid dynamics, surrogate model, response surface approximation, kriging and particle swarm optimization algorithm. J Braz. Soc. Mech. Sci. Eng. 45, 431 (2023). https://doi.org/10.1007/s40430-023-04355-y

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