Abstract
Purpose of Review
Maternal prenatal substance use presents a multilevel risk to child development and parenting. Although parenting interventions are increasingly integrated into substance use treatment, prenatal parenting processes have not received equal attention within these interventions. This article aims to synthesize the evidence on the specific prenatal risk factors affecting the development of early parenting of substance-using mothers, as well as interventions focusing on those factors.
Recent Findings
Both neurobiological and psychosocial risk factors affect the prenatal development of parenting in the context of maternal substance use. Maternal–fetal attachment, mentalization, self-regulation, and psychosocial risks are important in treatment and highly intertwined with abstinence. Although parenting interventions seem to be highly beneficial, most studies have not differentiated between pre- and postnatal interventions or described pregnancy-specific intervention elements.
Summary
Due to the salience of pregnancy in treating substance-using parents, interventions should begin prenatally and include pregnancy-specific parenting focus. Further research on prenatal interventions is warranted.
Introduction
Addiction during pregnancy poses a multilevel cumulative risk both to child development and to the development of parenting. Prenatal exposure to various legal and illegal substances has been robustly associated with problems in fetal growth, prematurity, and child health [1], with long-term consequences to self-regulation [2], mental health and behavioral problems [3], and substance use [4] in the developing child.
In addition to the proximal, direct biophysiological exposure effects, a variety of distal, psychosocial risks intrinsic to maternal substance use also greatly impact both child development and parenting [5]. These risks include socioeconomic problems, a lack of social support, being a single mother, or having a substance-using partner. Furthermore, mental health problems, including depression [6], post-traumatic stress disorder [7.••], and personality disorders, especially borderline personality disorder [8], are common among substance-using mothers. Finally, substance-using mothers typically have highly insecure and traumatic attachment histories [9], often characterized by repeated experiences of childhood maltreatment [10] and/or intimate partner violence in adulthood [11].
Early parent–child interaction is a central component mediating the cascade of proximal and distal risks to child development [12, 13]. Substance-using mothers often show pervasive problems in establishing sensitive interactions with their children [14] and display harsh, intrusive, or extremely withdrawn interaction patterns [15, 16], bordering on high risk for maltreatment and foster care placements [3, 17]. Parenting has gradually become one of the key targets of treatment for prenatally substance-using mothers [18].
Pregnancy has been described as a “window of opportunity,” featuring enhanced treatment motivation for substance-using mothers [19, 20]. There is also an increasing understanding of the role of pregnancy process in the development of parenting among substance-using mothers, with an emphasis on prenatal interventions targeting the maternal–fetal attachment bond as well as the maternal ability to reflect upon her baby, mothering, and her own attachment history [21, 22]. Furthermore, the roles of maternal prenatal stress and emotion regulation have been increasingly acknowledged as vital to prenatal substance use interventions [23, 24.••••]. Thus, this review article focuses, first, on the prenatal development of parenting and the multiple, interconnected neurobiological and psychosocial factors potentially affecting parenting among substance-using mothers. These factors and their interplay with a mother’s pre- and postnatal substance use, parenting, and child development are illustrated in Fig. 1. Second, we review the existing literature on prenatal interventions targeting this complex myriad of distal and proximal risk factors crucial to the development of parenting, as displayed in Table 1.
Neurobiological and psychosocial risk factors and pathways for maternal pre- and postnatal substance use, parenting, and child development
Review of Specific Risk Factors Potentially Affecting Prenatal Parenting Among Substance-Using Mothers
The Neurobiological Risks of Maternal Substance Use on Prenatal Parenting
Prenatal substance use impairs maternal parenting capacities by dysregulating three neural–hormonal systems vital to parenting [25, 26, 27.••••]. These systems include the maternal stress (glucocorticoid system), reward (dopamine), and affiliation (oxytocin) systems. Addiction and stress are intertwined, often leading to “dual” exposure to both substances and prenatal toxic stress [26, 27.••••]. Stressful events, especially parenting-related stress, also strongly trigger cravings and relapses [26], whereby prenatally distressed mothers are more likely to relapse [28, 29]. In terms of the reward system, substance-using mothers show blunted neural responses to positive cues from their infant in brain areas associated with rewards, suggesting that their reward circuits are co-opted by addiction instead of pleasure from the infant [26]. Finally, abnormalities in the maternal oxytocin system, a hormone crucial for high-quality maternal caregiving, associate with postnatal parenting problems [27.••••]. Mothers with addiction may also show an impoverished neural discrimination of infant facial and vocal emotional cues at least postnatally [30], although research remains lacking on whether these deficits are already present during pregnancy. Such findings suggest global deficits in the neural, substance-related mechanisms of caregiving that should be targeted already during pregnancy by simultaneously supporting abstinence, emerging motherhood, and a relationship with the fetus.
The Psychosocial Risks of Maternal Substance Use on Prenatal Parenting
The core psychological task of pregnancy is to develop maternal–fetal attachment, an increasingly intensive affective bond towards an unborn child, while simultaneously beginning to recognize the child as a separate person [31]. This process is also accompanied by the development of prenatal representations, that is, cognitive–emotional information-processing models of the unborn baby and oneself as a mother [32]. This forms the basis for a maternal identity and the relationship to the baby [33, 34]. During pregnancy, a shift occurs towards a new behavioral–motivational system, namely, a caregiving system [35], with a specific focus on attachment to and protection of the baby. Stern’s [34] concept of the “motherhood constellation” characterizes a mother’s gradual development of the capacity to fully concentrate on the infant’s needs and temporarily set aside other facets of her life. This process may be particularly difficult for mothers with addiction who are neurobiologically and psychologically motivated to preoccupation with substance use instead of the infant [26]. During pregnancy, mothers also reformulate their pre-existing representations of their partner to encompass fatherhood and being part of a family triad [34, 36.••]. Mothers with addiction are often single parents or experience difficulties with their partner, such as a partner’s substance use or intimate partner violence [5, 11], making prenatal representational processes more vulnerable. Mothers with addiction have indeed found to show more negative representations of their partner during pregnancy [37].
The mental and physical changes accompanying pregnancy often activate deeply embodied memories of one’s childhood attachment to their own parents, which serve as the building blocks for one’s own maternal identity [33, 34]. Since adverse childhood experiences are common in substance-using mothers [9], this process is inherently more complex and may lead to harmfully empty, narrow, or idealized view instead of a realistic maternal identity [37].
Maternal–fetal attachment and a mother’s prenatal representations are important because they provide the basis for actual postnatal mother–infant interactions and child attachment [38.••••, 39], possibly even predicting a risk for foster care [40]. More negative or unrealistic representations during pregnancy risk disturbing the quality of the postnatal relationship among substance-using mothers [37, 41], potentially translating into hostile, intrusive, or disengaged patterns of parenting. The role of the maternal–fetal relationship is also intertwined with prenatal substance exposure: mothers with a stronger attachment to their unborn child are also more likely to remain abstinent during pregnancy [42].
Maternal mentalization, operationalized as reflective functioning (RF), refers to her capacity to be curious and reflect upon emotions, experiences, thoughts, and intentions underlying behaviors and reactions, both her own and her child’s. This capacity is considered a crucial determinant of maternal interactive behavior [43, 44]. Parental RF is the caregiving-related capacity that mediates the effects of one’s childhood attachment experiences on one’s own parenting behaviors [44, 45]. Traumatic or insecure childhood attachment often hinders the mother’s full capacity to use RF to make sense of an infant’s cues and respond to them appropriately. Berthelot and colleagues [46.••] demonstrated that low maternal prenatal RF mediated the effects of childhood maltreatment on her prenatal mental health problems. Furthermore, a higher prenatal RF associates with a stronger sense of parenting competence experienced prenatally, and more intensive and positive maternal–fetal attachment among high-risk mothers [46.••, 47.••]. On average, substance-using mothers display a weak RF already during pregnancy [48, 49]. Prenatal level of RF has been found to predict both the quality of postnatal mother–infant interaction and the probability of abstinence in follow-up among substance-using mothers [48, 50].
The Role of Prenatal Emotions and Regulation During Pregnancy
Emotion regulation (ER) refers to “the extrinsic and intrinsic processes responsible for monitoring, evaluating, and modifying emotional reactions, especially their intensive and temporal features, to accomplish one’s goals” [51]. Thus, ER is vital to regulating distress and crucial in providing a parental regulatory capacity for infant distress. Deficits in ER often arise from trauma and mental health problems common among substance-using mothers. Substance use can be conceptualized as a deviant form of ER when more adaptive strategies are lacking [52, 53].
Pregnancy is a highly ambivalent period for substance-using mothers, simultaneously characterized by hope and motivation for change, but also by an increased vulnerability and emotional turmoil. Pregnancy-related activation of traumatic or adverse childhood memories, in conjunction with attempts to stop using substances, often lead to heightened distress and dysregulated negative emotions [9, 54] as well as intense feelings of guilt [55]. To help relieve this distress, prenatal interventions should also help women to identify new means of ER instead of substance use.
ER is also highly associated with the cognitive form of self-regulation, namely, executive functioning (EF) [56, 57]. Both capacities are also vital to maternal parenting [58] and associate with RF capacity [59, 60]. A recent study documented problems in EF among substance-using mothers [61]. EF implies the higher-order cognitive processes supporting effective problem-solving and goal-directed behavior [23], including the core functions of cognitive flexibility, working memory, and inhibitory control, as well as higher-order functions such as planning and self-monitoring [62]. EF may also greatly affect the flexibility and planning needed in parenting, as well as concrete problem-solving related to practical issues such as education or housing often relevant to mothers with addiction. ER and EF deficits are also central to both the initiation and maintenance of substance use [53, 63]. They should thus be jointly targeted in treatment, starting from pregnancy.
Review of Prenatal Interventions for Substance-Using Mothers
Table 1 summarizes studies about prenatal parenting interventions for substance-using mothers. For more than a decade, researchers have argued for early interventions specifically tailored to the needs and problems of parents with addiction, together with their children [48, 64]. Consensus exists that these families need comprehensive and integrated services comprising support for adverse life conditions, medical and psychosocial aid to treat addiction, and help for early parenting and developing attachment with their baby already prenatally [65–67]. In addition, maternal psychosocial needs should be addressed. For instance, a review of 38 women’s substance abuse treatment studies found that more positive treatment outcomes associated with the provision of practical issues such as prenatal care and childcare [68]. In the development of these services, trauma and mental health knowledge should be utilized [69.••].
Most previous studies have focused on postnatal substance use interventions. In a review of 21 postnatal outcome studies of integrated treatment models [65], most decreased substance use and parenting problems. A review of randomized control trials [70] indicated that substance use interventions that improve parenting practices and family functioning may also positively affect child development.
A meta-analysis by Milligan and colleagues [71] showed that the children of mothers in prenatal integrated services had less physical exposure effects related to fetal growth, prematurity, and birth complications than the children of untreated substance-using mothers. Mothers in integrated substance use interventions showed higher prenatal care attendance and lower rates of preterm births than those attending nonintegrated substance use interventions. Similarly, Niccols et al. [66, 67] indicated in their two review articles of pre- and postnatal interventions that, while all substance use interventions enhanced child growth and physical development, integrated rather than nonintegrated interventions were effective for child behavioral and social emotional functioning as well as for increasing parenting skills. However, most previous reviews have not differentiated between pre- and postnatally initiated interventions or the interventions they describe have not included a parenting component specifically tailored to pregnancy. Furthermore, the core components of prenatal substance use interventions have not been described. Here, we thus aimed to delineate these core intervention components, supplemented with the theoretical framework presented above emphasizing the various neurobiological and psychosocial risk factors affecting both pre- and postnatal parenting.
Prenatal parenting support interventions were initially developed in the 1990s largely in response to the crack cocaine epidemic. These interventions usually have a rather broad and practical focus [72], aiming to create positive changes in caregiving and a child’s home environment, as well as to prevent child neglect and abuse. Parental ability to mobilize social support is emphasized, including family and other social networks as well as professional help. McMurtrie and colleagues [73] found that the infants of long-term clients of the Parent and Child Enrichment (PACE) intervention had greater mean birth weight and less intrauterine growth retardation than infants in comparison groups. Fetal exposure to cocaine decreased dramatically among women enrolled for 42 or more days during their pregnancy. In addition, the home visit intervention run by Black and colleagues [72] decreased maternal drug use and improved parenting quality more than a comparison treatment without home visits. A more recent example of such an intervention was described by Grossmann and colleagues [74], where prenatal counseling for mothers with addiction was used as a part of a comprehensive medical intervention to improve hospital care for infants with neonatal abstinence syndrome (NAS). Counseling aimed to empower mothers in their important roles to be present and provide comfort to their infants as much as possible during NAS treatment. A comprehensive intervention was found to decrease the length and costs of hospital stays for infants and to reduce their need for morphine.
Attachment- and mentalizing-based interventions focus on improving the mother–child attachment relationship. Such interventions concurrently target the behavioral level, including maternal interactive behaviors, and the representational level, including the maternal pre- or postnatal representations of the baby and parenting as well as maternal RF. In relation to interactive behavior, mothers receive multilevel support in the interpretation of and response to their infant’s interaction signals (that is, being sensitive). Different from behavioral guidance alone, increased curiosity towards the child’s experiences and more accurate interpretations of a child’s interaction signals are considered key mechanisms of improving the parent–child interaction [64]. Postnatal or combined pre- and postnatal attachment- and mentalizing-based interventions [75, 76] have shown some promising results towards improving maternal RF, the mother–child interaction, and a child’s secure attachment among high-risk families.
Thus far, only a few studies have explored the effect of attachment- or mentalizing-based interventions during pregnancy. Pajulo and colleagues report in a series of papers on their recent innovative prenatal intervention study [22, 77.••••, 78.••••], where three four-dimensional interactive ultrasound sessions were offered to the intervention group during the third trimester of pregnancy. The model was based on pioneering work regarding an ultrasound consultation method developed by Boukydis and colleagues [79, 80], but with an added RF focus. The model aimed to increase maternal curiosity and interest in fetal development and foster a perspective helping the mother recognize her own experiences while watching the fetus and prompting her to think about becoming a mother to this particular child. This intervention also included a new pregnancy diary, with sections, for example, focused on gradually developing fetal capacities and personal characteristics week-by-week, mentalization of the baby and parenthood, and reflecting upon the pregnancy experience [22, 81]. The efficacy of the intervention was tested using a randomized control trial design in a maternity outpatient clinic specializing in the follow-up of substance-using mothers in collaboration with child welfare agencies. The intervention was well accepted, with an especially high attendance rate during the ultrasound sessions. Watching fetal facial features was self-reported by the mothers as particularly impressive. However, no statistically significant group differences were found in the outcomes explored and with the methodology used: self-reported prenatal mentalization and psychological distress, hospital record–based fetal drug exposure, and perinatal child outcome [77.••••, 78.••••].
Self-regulation-based intervention models are presented here as their own category, given their specific role for maternal emotion dysregulation during pregnancy, as described earlier. These models emphasize the role of the underlying affective and cognitive regulatory processes in parenting and addiction. For instance, Suchman et al. [64] suggested that mothers first need support in their own emotion regulation before they can facilitate their child’s developing self-regulation. As such, Milligan et al. [23] developed a comprehensive theoretical framework and treatment model, using self-regulation as depicted by emotion regulation (ER) and executive functioning (EF) as key target concepts. In their qualitative study using focus group interviews, they extracted specific counselor behaviors that explicitly supported ER (e.g., a nonjudgmental attitude and empathic listening) and EF (e.g., the simplification of procedures, action-oriented and goal-directed support, and parent coaching adapted to the maternal learning style).
Body-oriented interventions can be considered a specific type of self-regulation-based intervention and may benefit traumatized and substance-using mothers [82, 83]. Given that pregnancy and parenting a young infant are strongly embodied experiences, and emotion regulation has physiological components, body-oriented interventions may also be important during pregnancy. Thus far, only a few studies have incorporated body-oriented therapeutic modalities into the treatment of substance-using mothers, with none specifically tailored to pregnancy alone. Mindfulness-based interventions have proved feasible and effective among pregnant and parenting mothers of 0- to 3-year-old children attending drug treatment programs, ultimately improving parenting and dyadic attachment [84.••] and decreasing both general and parenting-related stress [85].
Trauma- and mental health–informed treatment models are theoretically close to attachment- and self-regulation models and are often used in combination with them. A mother’s complex, early-life history of attachment trauma, such as experiences of abuse and neglect, may biologically and behaviorally dysregulate her parenting capacity [86, 87]. Until recently, substance use disorder interventions have rarely been trauma-informed or included concurrent treatment for mental health disorders [88, 89], although both trauma activation and mental health issues may emerge when the mother abstains from substance use during pregnancy. Trauma-informed care emphasizes trustworthiness and openness throughout the entire treatment process, including elements of client safety, peer support, collaboration, cultural sensitivity, and empowerment of the client [90, 91]. This approach also alleviates the stigmatization of substance-using individuals who, instead of being regarded as “deficient” or “unmotivated,” are now considered from the perspective of having unresolved trauma. For example, the C.A.R.E model combines trauma-informed treatment elements pre- and postnatally for mothers in residential care for substance use [69.••]. Clinicians using the model have observed changes in their clients’ self-efficacy, trauma symptoms, anxiety, depression, and sleep disturbances [69.••].
Most of the approaches described above include several shared components which are specifically embedded together in more comprehensive treatment programs. Inpatient or residential treatment can be employed to treat mothers with severe substance use disorders, representing the most comprehensive and multifocus treatment models for pregnant women, usually extending into the postpartum period. Residential treatment has proved effective in terms of abstinence, employment, psychological distress, parenting, and criminal problems [92]. Moreover, such programs have the possibility of focusing on multiple issues simultaneously: substance use, general parenting skills, reinforcing parent–child attachment, psychoeducation, practical support, and the relevant therapeutic and medical care [48, 93].
BRIGHT, an attachment- and trauma-focused intervention that can be used in residential settings, is based on evidence-based child–parent psychotherapy (CPP) treatment [94]. Substance abuse treatment and concrete assistance with daily life problems are additional essential components of BRIGHT. Child development is supported through developmental guidance and the use of activities such as play and physical contact. Enhancing maternal RF and ER are also included in BRIGHT. Women with the highest distress have shown a significant decrease in mental health symptoms and an improved RF as a result of this intervention [95].
Vazquez and Bergin [96.••] described their 90-day inpatient intervention program for substance-using pregnant women. In addition to more traditional treatment elements (e.g., psychoeducation, sobriety classes, medically assisted detox, and case management), mothers received a combination of parenting education and an individual therapeutic program. The intervention reduced parenting stress, isolation, and depressive symptoms, and increased parenting competence.
Pajulo and colleagues [48, 97] described “Holding tight,” the residential national treatment model, which has been under continuous development in Finland since the late 1990s for mothers with a severe substance use disorder. The program simultaneously targets parenting and substance use from pregnancy onwards, emphasizing increasing maternal RF and the quality of the mother–child relationship in everyday interaction situations. Parenting support is also offered in separate group meetings, promoting peer support, individual counseling, and through daily-life practical assistance. Referral to mental health treatment, help in managing the authorities (e.g., social services, legal issues), daily chores, and enhancing social networks may also be addressed based on individual’s needs. In the first evaluation [48], parental mentalization capacity was found to increase during the intervention from pregnancy to postpartum. In addition, mothers with a higher RF at the end of the residential treatment period relapsed less frequently during the 2-year follow-up period and were more likely to retain custody of their child. Currently, we (the authors of this paper) are carrying out a new evaluation of the entire Finnish “Holding tight” program, focusing on parenting, mentalization, and ER.
One specific form of residential care is involuntary treatment. Norway is the only European country with legislation allowing for the involuntary treatment of pregnant mothers with addiction in cases where voluntary treatment is insufficient to safeguard fetal health. Mothers themselves often seek this type of treatment since they feel powerless to abstain [98]. Maternal–fetal attachment has been found to improve in both voluntary and involuntary treatment contexts, interestingly, perhaps more so during involuntary care [21]. According to a qualitative study, viewing a fetal ultrasound was experienced as quite important for mothers in involuntary treatment, allowing them to emotionally attach to the unborn child [98].
Conclusions
During the past 30 years, the development of intervention models has evolved from general parenting support and skills training into more specific attachment-based interventions that promote maternal reflective functioning, emotion regulation, and recovery from trauma and mental health problems. Similarly, there has been a trend from previously fragmented services targeting either substance use or parenting into more effective integrated, multiservice “one-stop shop” treatment models that better serve the multiple biomedical and psychosocial needs of these mothers [99].
While many countries provide these types of comprehensive services, Meixner et al. [99] in their review stated that services remain too heterogeneous, with programs designed to match community needs and resources, whereas program evaluations and the dissemination of findings about best practices largely remain lacking. More comprehensive theoretical models are therefore needed to guide these perinatal services. This article attempts to delineate the most crucial components in the care related to prenatal substance use and parenting.
Given the increased understanding of pregnancy processes, treatment programs increasingly encompass the prenatal period, while often comprehensively extending into the postnatal period. Although precious few intervention studies have clearly differentiated whether certain treatment elements are particularly important or helpful during pregnancy, there have been a few promising attempts [22].
Supporting maternal–fetal attachment represents a crucial component in most modern, pregnancy-focused substance use interventions. Essentially, pregnancies are often unplanned, and substance-using mothers may be biologically and psychologically motivated by addiction rather than motherhood, thereby hindering the development of maternal–fetal attachment and other pregnancy processes. A higher maternal RF is suggested to serve as an important route towards a stronger maternal–fetal attachment.
However, little scientific evidence exists regarding how precisely and how effectively different elements and routes affect substance-using pregnant women’s situations and parenting. Randomized control trial studies are rare in the field. Although such studies would provide the most rigorous evidence of effectiveness, it is often not ethically or practically possible to conduct them in these vulnerable, high-risk populations. Some new, innovative assessment methods have also been applied in the field of prenatal substance use. For instance, ecological momentary assessment [7.••] enables multiple daily-life assessments, thus providing a way to measure the flow of temporal associations between different risks and protective factors related to prenatal substance use, parenting, and their interventions.
Additional new avenues may include incorporating body-oriented therapies such as mindfulness to prenatal interventions in order to reduce stress and provide a space for developing motherhood [84.••]. Maternal substance use disorder is often associated with a history of unresolved trauma, where body-oriented interventions as well as general trauma-informed care are particularly important. Furthermore, work with other high-risk populations has suggested that interventions relying on experiential elements that support the pregnancy process, such as stroking the baby in the womb, singing, or talking to them, may benefit the mother–infant relationship [100, 101.••]. Yet, research among substance-using mothers remains lacking.
New digital, technology-assisted treatment models may also show promise. While Hai and colleagues [102] in their review found that digitally based interventions (e.g., games or virtual reality technologies) were not necessarily effective among substance-using women, little is known regarding if such interventions could be helpful as part of more comprehensive interventions. To our knowledge, digital interventions have not yet been specifically developed for pregnancy or for parenting among substance-using mothers and therefore their utility as part of prenatal interventions remains unclear. Such tools may serve to replace the mother’s reward system with pleasure related to the baby instead of substances. Virtual treatments have already proved successful for other trauma patients [103.••] and may be useful among pregnant substance-using mothers in the treatment of both trauma symptoms and parenting.
Pregnancy should be viewed as a crucial phase in the emerging mother–child relationship, with services designed for high-risk mothers starting as early as possible during pregnancy. Identifying mothers in need is, however, challenging, since pregnant mothers are often especially reluctant to disclose their substance use to healthcare providers, and adopt harmful strategies to avoid detection, such as isolation and missing prenatal appointments [104, 105]. Substance-using mothers often fear stigmatization, losing custody of their child, or are reluctant to leave other family members in order to attend treatment. Furthermore, practical issues, such as a lack of childcare and transportation, constitute obstacles to treatment access [106.••].
Opportunities to receive treatment without automatic penalties should be more easily available as well as better access to comprehensive, multilevel care [106.••, 107]. Services need to be continuum-based such that mothers receive care from the same providers from pregnancy through the postnatal period, in order to establish trusting, secure relationships. Due to the highly complex nature and recurring relapse risks inherent in substance use, early pre- and postnatal treatments also need to feature a long-term focus, taking into account the mother, child, and possible partner as well as others in their family and social networks, and establishing careful plans for follow-up and monitoring.
Moreover, focusing on fathers has been notoriously insufficient in the research concerning parenting interventions for substance-using mothers [108], probably because many mothers are single or the fathers themselves have substance use disorders and may not always be motivated for treatment. However, fathers participating in substance use treatment have reported mostly positive attitudes towards parenting interventions [109]. Even considering legal addictions, such as nicotine, few interventions involve fathers, despite the fact that fathers’ participation has proved helpful for mothers in quitting smoking during pregnancy. Huizink et al. [110] and Neger and Printz [65] suggested that the involvement of significant others in interventions may also help maintain the beneficial changes following the end of an intervention. Many substance-using individuals become isolated after reaching abstinence, since many of their previous networks may have consisted of others also using substances. Support from a peer group and in finding community resources may be particularly useful. Peer support may also help individuals to cope with the guilt inherent in maternal substance use.
The psychosocial and medical realities of these women should always be kept in mind when designing interventions. Parenting interventions alone may not lead to reduced substance use. Furthermore, general parenting interventions may not suffice for this special high-risk population, but they need tailored interventions that also address their unique psychosocial and mental health needs [111.••]. Despite the importance of resolving trauma and attachment issues, practical realities such as housing-, poverty-, and unemployment-related issues should always be equally addressed.
In summary, we suggest that both prenatal inpatient and outpatient interventions should include multidisciplinary and multifaceted help addressing the medical follow-up of pregnancy and child development, need for substitution medication, practical daily-life help, psychological treatment for substance use, including comorbid mental health problems, and support on the developing maternal–fetal attachment. The maternal–fetal relationship can be supported, for example, through group or individual activities helping mothers to connect with the baby in the womb, such as singing or touching the belly, viewing the baby via an ultrasound, or reflecting upon pregnancy or the baby through writing or talking. The baby may be viewed as an active agent in helping mothers to remain abstinent. Mindfulness, yoga, or other body-oriented interventions should be considered in an effort to ameliorate trauma symptoms and ER problems typical among these mothers. Such interventions could potentially prevent fetal exposure to prenatal stress, as well as provide new ways to regulate emotions without substances. The entire family, and extended family, could be included in treatment. Furthermore, treatments should always continue long enough from pregnancy until the postpartum period (and beyond), including long-term support or periodic follow-up of maternal well-being and child development, preferably in the context of reliable, long-term relationships with the same practitioner(s). This treatment continuum lies at the core of trauma-informed care for vulnerable mothers with insecure attachment histories and substance use disorders.
References
Papers of particular interest, published recently, have been highlighted as: • Of importance •• Of major importance
Smith VC, Wilson CR, COMMITTEE ON SUBSTANCE USE AND PREVENTION. Families affected by parental substance use. Pediatrics. 2016;138(2):e20161575. https://doi.org/10.1542/peds.2016-1575.
Eiden RD, Schuetze P, Shisler S, Huestis MA. Prenatal exposure to tobacco and cannabis: effects on autonomic and emotion regulation. Neurotoxicol Teratol. 2018. https://doi.org/10.1016/j.ntt.2018.04.007.
Koponen AM, Nissinen NM, Gissler M, Sarkola T, Autti-Rämö I, Kahila H. Cohort profile: ADEF Helsinki—a longitudinal register-based study on exposure to alcohol and drugs during foetal life. Nordic Stud Alcohol Drugs. 2020. https://doi.org/10.1177/1455072519885719.
Cornelius MD, Genna NM, Goldscmidt L, Larkby C, Day NL. Prenatal alcohol and other early childhood adverse exposures: direct and indirect pathways to adolescent drinking. Neurotoxicol Teratol. 2016. https://doi.org/10.1016/j.ntt.2016.03.001.
Conners NA, Bradley RH, Mansell LW, Liu JY, Roberts TJ, Burgdorf K, Herrell JM. Children of mothers with serious substance abuse problems: an accumulation of risks. Am J Drug Alcohol Abuse. 2003. https://doi.org/10.1081/ADA-120026258.
Chapman SLC, Wu LT. Postpartum substance use and depressive symptoms: a review. Women Health. 2013;53(5):479–503. https://doi.org/10.1080/03630242.2013.804025.
Sanjuan PM, Pearson MR, Poremba C, Amaro HLA, Leeman L. An ecological momentary assessment study examining posttraumatic stress disorder symptoms, prenatal bonding, and substance use among pregnant women. Drug Alcohol Depend. 2019. https://doi.org/10.1016/j.drugalcdep.2018.11.019Methodologically important study using EMA assessment to address the complex timing effects between variables relevant for maternal prenatal substance use and parenting.
Trull TJ, Freeman LK, Vebares TJ, Choate AM, Helle AC, Wycoff AM. Borderline personality disorder and substance use disorders: an updated review. Borderline Personal Disord Emot Dysregul. 2018. https://doi.org/10.1186/s40479-018-0093-9.
Isosävi S, Flykt M, Belt R, Posa T, Kuittinen S, Puura K, Punamäki RL. Attachment representations among substance-abusing women in transition to motherhood: implications for prenatal emotions and mother-infant interaction. Attach Hum Dev. 2016. https://doi.org/10.1080/14616734.2016.1151904.
Edalati H, Krank MD. Childhood maltreatment and development of substance use disorders: a review and a model of cognitive pathways. Trauma Violence Abuse. 2016. https://doi.org/10.1177/1524838015584370.
Devries KM, Child JC, Bacchus LJ, Mak J, Falder G, Graham K, Watts C, Heise L. Intimate partner violence victimization and alcohol consumption in women: a systematic review and meta-analysis. Addiction. 2014. https://doi.org/10.1111/add.12393.
Eiden RD, Lessard J, Colder CR, Livingston J, Casey M, Leonard KE. Developmental cascade model for adolescent substance use from infancy to late adolescence. Dev Psychol. 2016. https://doi.org/10.1037/dev0000199.
Ettekal I, Eiden RD, Nickerson AB, Molmar DS, Schuetze P. Developmental cascades to children’s conduct problems: the role of prenatal substance use, socioeconomic adversity, maternal depression and sensitivity, and children’s conscience. Dev Psychopathol. 2020. https://doi.org/10.1017/S095457941800144X.
Hatzis D, Dawe S, Harnett P, Harlow J. Quality of caregiving in mothers with illicit substance use: a systematic review and meta-analysis. Subst Abuse. 2017. https://doi.org/10.1177/1178221817694038.
Belt R, Flykt M, Punamäki RL, Pajulo M, Posa T, Biringen Z, Tamminen T. Psychotherapy groups to enhance mental health and early dyadic interaction among drug abusing mothers. Infant Ment Health J. 2012. https://doi.org/10.1002/imhj.21348.
Salo S, Politi J, Tupola S, Biringen Z, Kalland M, Halmesmäki E, Kahila H, Kivitie-Kallio S. Early development of opioid-exposed infants born to mothers in buprenorphine-replacement therapy. J Reprod Infant Psychol. 2010. https://doi.org/10.1080/02646830903219109.
Kepple NJ. The complex nature of parental substance use: examining past year and prior use behaviors as correlates of child maltreatment frequency. Subst Use Misuse. 2017. https://doi.org/10.1080/10826084.2016.1253747.
Suchman N, DeCoste C, Rosenberger P, McMahon TJ. Attachment-based intervention for substance-using mothers: a preliminary test of the proposed mechanisms of change. Infant Ment Health J. 2012. https://doi.org/10.1002/imhj.21311.
Le TL, Kenaszchuk C, Milligan K, Urbanoski K. Levels and predictors of participation in integrated treatment programs for pregnant and parenting women with problematic substance use. BMC Public Health. 2019. https://doi.org/10.1186/s12889-019-6455-4.
Van Scoyoc A, Harrison JA, Fisher PA. Beliefs and behaviors of pregnant women with addictions awaiting treatment initiation. Child Adolesc Social Work J. 2017. https://doi.org/10.1007/s10560-016-0474-0.
Myra SM, Ravndal E, Torsteinsson VW, Ofstif AKS. Pregnant substance abusers in voluntary and coercive treatment in Norway: therapists’ reflections on change processes and attachment experiences. J Clin Nurs. 2017. https://doi.org/10.1111/jocn.14067.
Pajulo H, Pajulo M, Jussila H, Ekholm E. Substance-abusing pregnant women: prenatal intervention using ultrasound consultation and mentalization to enhance the mother–child relationship and reduce substance use. Infant Ment Health J. 2016. https://doi.org/10.1002/imhj.21574.
Milligan K, Usher AM, Urbanoski KA. Supporting pregnant and parenting women with substance-related problems by addressing emotion regulation and executive function needs. Addict Res Theory. 2017. https://doi.org/10.1080/16066359.2016.1259617.
Rutherford HJV, Mayes LC. Parenting stress: a novel mechanism of addiction vulnerability. Neurobiol Stress. 2019;11:100172. https://doi.org/10.1016/j.ynstr.2019.100172An important article illuminating on the interplay between addiction and stress which underlies parenting difficulties.
Kim S, Kwok S, Mayes LC, Potenza MN, Rutherford HJV, Strathearn L. Early adverse experience and substance addiction: dopamine, oxytocin, and glucocorticoid pathways. Ann N Y Acad Sci. 2017;1394(1):74–91. https://doi.org/10.1111/nyas.13140.
Rutherford HJV, Gerig G, Gouttard S, Potenza MN, Mayes LC. Investigating maternal brain structure and its relationship to substance use and motivational systems. Yale J Biol Med. 2015;88:211–7.
Strathearn L, Mertens CE, Mayes L, Rutherford H, Purva R, Guifeng X, Potenza MN, Kim S. Pathways relating the neurobiology of attachment to drug addiction. Front Psychiatry. 2019. https://doi.org/10.3389/fpsyt.2019.00737An important article illuminating the three neural–hormonal pathways through which addiction forms a risk for parenting capacities.
Massey SH, Neiderhiser JM, Shaw DS, Leve LD, Ganiban JM, Reiss D. Maternal self-concept as a provider and cessation of substance use during pregnancy. Addict Behav. 2012. https://doi.org/10.1016/j.addbeh.2012.04.002.
Orr ST, Blazer DG, Orr CA. Maternal prenatal depressive symptoms, nicotine addiction, and smoking-related knowledge, attitudes, beliefs, and behaviors. Matern Child Health J. 2012. https://doi.org/10.1007/s10995-011-0822-9.
Lowell AF, Maupin AN, Landi N, Potenza MN, Mayes LC, Rutherford HJV. Substance use and mothers’ neural responses to infant cues. Infant Ment Health J. 2020. https://doi.org/10.1002/imhj.21835.
Ammaniti M, Trentini C, Menozzi F, Tambelli R. Transition to parenthood: studies of intersubjectivity in mothers and fathers. In: Emde RN, Leuzinger-Bohleber M, editors. Early parenting and prevention of disorder: psychoanalytic research at interdisciplinary frontiers. London: Karnac; 2014. p. 129–64.
Ammaniti M, Baumgartner E, Candelori C, Perucchini P, Pola M, Tambelli R, Zampino F. Representations and narratives during pregnancy. Infant Ment Health J. 1992. https://doi.org/10.1002/1097-0355(199223)13:2%3c167::AID-IMHJ2280130207%3e3.0.CO;2-M.
Slade A, Cohen LJ, Sadler LS, Miller M. The psychology and psychopathology of pregnancy: reorganization and transformation. In: Zeanah CH, editor. Handbook of infant mental health. New York: Guilford Press; 2009. p. 22–39.
Stern D. The motherhood constellation. A unified view of parent-infant psychotherapy. New York: Basic Books; 1995.
Solomon G, George C. Defining the caregiving system: towards a theory of caregiving. Infant Ment Health J. 1996. https://doi.org/10.1002/(SICI)1097-0355(199623)17:3%3c183::AID-IMHJ1%3e3.0.CO;2-Q.
Kuersten-Hogan R. Bridging the gap across the transition to coparenthood: triadic interactions and coparenting representations from pregnancy through 12 months postpartum. Front Psychol. 2017. https://doi.org/10.3389/fpsyg.2017.00475Describes the continuum of prenatal coparenting representations into postnatal period.
Flykt M, Punamäki RL, Belt R, Biringen Z, Salo S, Posa T, Pajulo M. Maternal representations and emotional availability among drug-abusing and nonusing mothers and their infants. Infant Ment Health J. 2012. https://doi.org/10.1002/imhj.21313.
Foley S, Hughes C. Great expectations? Do mothers’ and fathers’ prenatal thoughts and feelings about the infant predict parent-infant interaction quality? A meta-analytic review. Dev Rev. 2018;48:40–54. https://doi.org/10.1016/j.dr.2018.03.007An important meta-analytic review on why parental prenatal bond to the fetus and their prenatal representations is important.
Tambelli R, Trentini C, Dentale F. Predictive and incremental validity of parental representations during pregnancy on child attachment. Front Public Health. 2020. https://doi.org/10.3389/fpubh.2020.439449.
Terry M, Finger B, Lyons-Ruth K, Sadler LS, Slade A. Hostile/helpless maternal representations in pregnancy and later child removal: a pilot study. Infant Ment Health J. 2021. https://doi.org/10.1002/imhj.21887.
Pajulo M, Savonlahti E, Sourander A, Piha J, Helenius H. Maternal representations, depression and interactive behaviour in the postnatal period: a brief report. J Reprod Infant Psychol. 2004. https://doi.org/10.1080/0264683042000205954.
Massey SH, Bublitz MH, Magee SR, Salisbury A, Niaura RS, Wakschlag LS, Stroud LR. Maternal–fetal attachment differentiates patterns of prenatal smoking and exposure. Addict Behav. 2015. https://doi.org/10.1016/j.addbeh.2015.01.028.
Camoirano A. Maternal reflective functioning, attachment, and the transmission gap: a preliminary study. Front Psychol. 2017. https://doi.org/10.3389/fpsyg.2017.00014.
Slade A, Grienenberger J, Bernbach E, Levy D, Locker A. Maternal reflective functioning, attachment, and the transmission gap: a preliminary study. Attach Hum Dev. 2005. https://doi.org/10.1080/14616730500245880.
Fonagy P, Steele M, Steele H, Moran GS, Higgitt AC. The capacity for understanding mental states: the reflective self in parent and child and its significance for security of attachment. Infant Ment Health J. 1991. https://doi.org/10.1002/1097-0355(199123)12:3%3c201::AID-IMHJ2280120307%3e3.0.CO;2-7.
Berthelot N, Lemieux R, Garon-Bissonnette J, Lacharité C, Muzik M. The protective role of mentalizing: reflective functioning as a mediator between child maltreatment, psychopathology and parental attitude in expecting parents. Child Abuse Negl. 2019. https://doi.org/10.1016/j.chiabu.2019.104065Validates the predictive role of maternal prenatal RF on postnatal outcomes.
Rohder K, MacBeth A, Davidsen KA, Gumley A, Brennan J, George C, Harder S. Antenatal caregiving representations and perinatal behavior in mothers with severe lifetime psychopathology. Infant Ment Health J. 2020. https://doi.org/10.1002/imhj.21824Validates the predictive role of maternal prenatal RF on postnatal outcomes.
Pajulo M, Pyykkönen N, Kalland M, Sinkkonen J, Helenius H, Punamäki RL, Suchman N. Substance-abusing mothers in residential treatment with their babies: importance of pre- and postnatal maternal reflective functioning. Infant Ment Health J. 2012. https://doi.org/10.1002/imhj.20342.
Smaling HJA, Huijbregts SCJ, Suurland J, Van Der Heijden KB, Van Goozen SHM, Swaab H. Prenatal reflective functioning in primiparous women with a high-risk profile. Infant Ment Health J. 2015;36(3):251–61. https://doi.org/10.1002/imhj.21506.
Smaling HJA, Huijbregts SCJ, Suurland J, van der Heidjen KB, Mesman J. Prenatal reflective functioning and accumulated risk as predictors of maternal interactive behavior during free play, the still-face paradigm, and two teaching tasks. Infancy. 2016. https://doi.org/10.1111/infa.12137.
Thompson RA. Emotion regulation: a theme in search of definition. Monogr Soc Res Child Dev. 1994. https://doi.org/10.1111/j.1540-5834.1994.tb01276.x.
Khantzian EJ. The self-medication hypothesis and attachment theory: pathways for understanding and ameliorating addictive suffering. In: Gill R, editor. Addictions from an attachment perspective: do broken bonds and early trauma lead to addictive behaviours? London: Karnac Books; 2014. p. 33–56.
Linn BK, Stasiewicz PR, Fillo J, Bradizza CM. The great disrupter: relationship of alexithymia to emotion regulation processes and smoking among pregnant women. Subst Use Misuse. 2020. https://doi.org/10.1080/10826084.2020.1729198.
Punamäki RL, Belt R, Posa T. Emotions during the transition to parenthood among substance-abusing mothers: intensity, content and intervention effects. J Reprod Infant Psychol. 2013;31(3):222–44. https://doi.org/10.1080/02646838.2013.803046.
Silva SA, Pires AP, Guerreiro C, Carroso A. Balancing motherhood and drug addiction: the transition to parenthood of addicted mothers. J Health Psychol. 2012. https://doi.org/10.1177/1359105312443399.
Pruessner L, Barnow S, Holt DV, Joormann J, Schulze K. A cognitive control framework for understanding emotion regulation flexibility. Emotion. 2020. https://doi.org/10.1037/emo0000658.
Schmeichel BJ, Tang D. Individual differences in executive functioning and their relationship to emotional processes and responses. Curr Dir Psychol Sci. 2015. https://doi.org/10.1177/0963721414555178.
Crandall AA, Deater-Deckard K, Riley AW. Maternal emotion and cognitive control capacities and parenting: a conceptual framework. Dev Rev. 2015. https://doi.org/10.1016/j.dr.2015.01.004.
Rutherford HJV, Byrne SP, Crowley MJ, Bornstein J, Bridgett DJ, Mayes LC. Executive functioning predicts reflective functioning in mothers. J Child Fam Stud. 2018. https://doi.org/10.1007/s10826-017-0928-9.
Schultheis AM, Mayes LC, Rutherford HJV. Associations between emotion regulation and parental reflective functioning. J Child Fam Stud. 2019. https://doi.org/10.1007/s10826-018-01326-z.
Håkansson U, Halsa A, Söderström K, Skårderud F, Oie MG. Keeping mind in mind: mentalizing and executive functioning in substance-abusing infant mothers: effect on dyadic relationship and infant outcome. Subst Abuse. 2015. https://doi.org/10.4137/SART.S23502.
Diamond A. Executive functions. Annu Rev Psychol. 2013. https://doi.org/10.1146/annurev-psych-113011-143750.
Blume AW, Marlatt GA. The role of executive cognitive functions in changing substance use: what we know and what we need to know. Ann Behav Med. 2009. https://doi.org/10.1007/s12160-009-9093-8.
Suchman N, Pajulo M, DeCoste C, Mayes L. Parenting interventions for drug-dependent mothers and their young children: the case for an attachment-based approach. Fam Relat. 2006. https://doi.org/10.1111/j.1741-3729.2006.00371.x.
Neger EN, Prinz RJ. Interventions to address parenting and parental substance abuse: conceptual and methodological considerations. Clin Psychol Rev. 2015. https://doi.org/10.1016/j.cpr.2015.04.004.
Niccols A, Milligan K, Smith A, Sword W, Thabane L, Henderson J. Integrated programs for mothers with substance abuse issues and their children: a systematic review of studies reporting on child outcomes. Child Abuse Negl. 2012. https://doi.org/10.1016/j.chiabu.2011.10.007.
Niccols A, Milligan K, Sword W, Thabane L, Henderson J, Smith A. Integrated programs for mothers with substance abuse issues: a systematic review of studies reporting on parenting outcomes. Harm Reduct J. 2012. https://doi.org/10.1186/1477-7517-9-14.
Ashley OS, Marsden ME, Brady TM. Effectiveness of substance abuse treatment programming for women: a review. Am J Drug Alcohol Abuse. 2003. https://doi.org/10.1081/ADA-120018838.
Bosk EA, Paris R, Hanson KE, Ruisard D, Suchman NE. Innovations in child welfare interventions for caregivers with substance use disorders and their children. Child Youth Serv Rev. 2019;101:99–112. https://doi.org/10.1016/j.childyouth.2019.03.040An article presenting four pre- and postnatal interventions that take into account the multilevel risk factors among substance-using women.
Calhoun S, Conner E, Miller M, Messina N. Improving the outcomes of children affected by parental substance abuse: a review of randomized controlled trials. Subst Abuse Rehabil. 2015. https://doi.org/10.2147/SAR.S46439.
Milligan K, Niccols A, Sword W, Thabane L, Henderson J, Smith A. Birth outcomes for infants born to women participating in integrated substance abuse treatment programs: a meta-analytic review. Addict Res Theory. 2011. https://doi.org/10.3109/16066359.2010.545153.
Black MM, Nair P, Kight C, Wachtel R, Roby P, Schuler M. Parenting and early development among children of drug-abusing women: effects of home intervention. Pediatrics. 1994;94:440–8.
McMurtrie C, Rosenberg KD, Kerker BD, Kan J, Graham EH. A unique treatment program for pregnant and postpartum substance-using women in New York City: results of a pilot project, 1990–1995. Am J Drug Alcohol Abuse. 1999. https://doi.org/10.1081/ada-100101887.
Grossman MR, Berkwitt AK, Osborn RR, Xu Y, Esserman DA, Shapiro ED, Bizzarro MJ. An initiative to improve the quality of care of infants with neonatal abstinence syndrome. Pediatrics. 2017. https://doi.org/10.1542/peds.2016-3360.
Suchman N, DeCoste CL, McMahon TJ, Dalton R, Mayes LC, Borelli J. Mothering from the Inside Out: results of a second randomized clinical trial testing a mentalization-based intervention for mothers in addiction treatment. Dev Psychopathol. 2017. https://doi.org/10.1017/S0954579417000220.
Slade A, Holland ML, Ordway MR, Carlson EA, Jeon S, Close N, Mayes LC, Sadler LS. Minding the Baby®: enhancing parental reflective functioning and infant attachment in an attachment-based, interdisciplinary home visiting program. Dev Psychopathol. 2020. https://doi.org/10.1017/S0954579418001463.
Jussila H, Ekholm E, Pajulo M. A new parental mentalization focused ultrasound intervention for substance using pregnant women. Effect on self-reported prenatal mental health, attachment and mentalization in a randomized and controlled trial. Int J Ment Health Addict. 2020;19(4):947–70. https://doi.org/10.1007/s11469-019-00205-yRepresents an RCT study on pregnancy-specific substance use intervention.
Jussila H, Pajulo M, Ekholm E. A novel 4D ultrasound parenting intervention for substance using pregnant women in Finland: participation in obstetric care, fetal drug exposure, and perinatal outcomes in a randomized controlled trial. Matern Child Health J. 2019;24(1):90–100. https://doi.org/10.1007/s10995-019-02773-wRepresents an RCT study on pregnancy-specific substance use intervention.
Boukydis Z. Ultrasound consultation to reduce risk and increase resilience in pregnancy. Ann N Y Acad Sci. 2006. https://doi.org/10.1196/annals.1376.032.
Boukydis Z. Collaborative consultation with parents and infants in the perinatal period. Baltimore: Brookes Publishing; 2012.
Pajulo M, Ekholm E, Kallioinen O, Kortekangas L, Von Koskull M, Andersson G. Vauva mielessä – raskauspäiväkirja odottavalle äidille. (The baby in mind—a new RF focused pregnancy diary). Helsinki: Folkhälsans förbund; 2011.
Ong I. Treating complex trauma survivors: a trauma-sensitive yoga (TSY)-informed psychotherapeutic approach. J Creat Ment Health. 2021;16(2):182–95. https://doi.org/10.1080/15401383.2020.1761498.
Price CJ, Thompson EA, Crowell SE, Pike K, Cheng SC, Parent S, Hooven C. Immediate effects of interoceptive awareness training through mindful awareness in body-oriented therapy (MABT) for women in substance use disorder treatment. Subst Abuse. 2019;40(1):102–15. https://doi.org/10.1080/08897077.2018.1488335.
Gannon MA, Mackenzie M, Hand DJ, Short V, Abatemarco D. Application of a RE-AIM Evaluation Framework to test integration of a mindfulness based parenting intervention into a drug treatment program. Matern Child Health J. 2019;23(3):298–306. https://doi.org/10.1007/s10995-018-02715-yOne of the first attempts in integrating body-oriented mindfulness intervention with drug treatment program aimed for mothers and their young children.
Short VL, Gannon M, Weingarten W, Kaltenbach K, LaNoue M, Abatemarco DJ. Reducing stress among mothers in drug treatment: a description of a mindfulness based parenting intervention. Matern Child Health J. 2017;21(6):1377–86. https://doi.org/10.1007/s10995-016-2244-1.
Erickson N, Julian M, Muzik M. Perinatal depression, PTSD, and trauma: impact on mother–infant attachment and interventions to mitigate the transmission of risk. Int Rev Psychiatry. 2019;31(3):245–63. https://doi.org/10.1080/09540261.2018.1563529.
Kim S, Fonagy P, Allen J, Strathearn L. Mothers’ unresolved trauma blunts amygdala response to infant distress. Soc Neurosci. 2014;9(4):352–63. https://doi.org/10.1080/17470919.2014.896287.
Flanagan JC, Korte KJ, Killeen T, Back SE. Concurrent treatment of substance use and PTSD. Curr Psychiatry Rep. 2016. https://doi.org/10.1007/s11920-016-0709-y.
Grella CE, Stein JA. Impact of program services on treatment outcomes of patients with comorbid mental and substance use disorders. Psychiatr Serv. 2006. https://doi.org/10.1176/ps.2006.57.7.1007.
Goodman R. Contemporary trauma theory and trauma-informed care in substance use disorders: a conceptual model for integrating coping and resilience. Adv Soc Work. 2017;18(1):186–201. https://doi.org/10.18060/21312.
Kirst M, Aery A, Matheson FI, Stergiopoulos V. Provider and consumer perceptions of trauma informed practices and services for substance use and mental health problems. Int J Ment Health Addict. 2017. https://doi.org/10.1007/s11469-016-9693-z.
Lester BM, Twomey JE. Treatment of substance abuse during pregnancy. Womens Health. 2008. https://doi.org/10.2217/17455057.4.1.67.
McComish JF, Greenberg R, Ager J, Essenmacher L, Orgain LS, Bacik WJ. Family-focused substance abuse treatment: a program evaluation. J Psychoactive Drugs. 2003;35(3):321–31. https://doi.org/10.1080/02791072.2003.10400015.
Lieberman AF, Van Horn P, Ippen CG. Toward evidence-based treatment: child-parent psychotherapy with preschoolers exposed to marital violence. J Am Acad Child Adolesc Psychiatry. 2005. https://doi.org/10.1097/01.chi.0000181047.59702.58.
Paris R, Herriott A, Holt M, Gould K. Differential responsiveness to a parenting intervention for mothers in substance abuse treatment. Child Abuse Negl. 2015. https://doi.org/10.1016/j.chiabu.2015.09.007.
Vazquez VE, Bergin A. Effectiveness of a specialized inpatient treatment program for substance and alcohol abusing pregnant women. J Drug Issues. 2019. https://doi.org/10.1177/0022042619831986Describes effectiveness of an inpatient treatment program aimed for pregnant substance-abusing mothers.
Pajulo M, Suchman N, Kalland M, Mayes L. Enhancing the effectiveness of residential treatment for substance abusing pregnant and parenting women: focus on maternal reflective functioning and mother-child relationship. Infant Ment Health J. 2006. https://doi.org/10.1002/imhj.20100.
Myra SM, Ravndal E, Torsteinsson VW, Wiig EM. Pregnant substance-abusing women in involuntary treatment: attachment experiences with the unborn child. Nordic Stud Alcohol Drugs. 2016. https://doi.org/10.1515/nsad-2016-0023.
Meixner T, Milligan K, Urbanoski K, McShane K. Conceptualizing integrated service delivery for pregnant and parenting women with addictions: defining key factors and processes. J Addict Med. 2016. https://doi.org/10.1097/02024458-201609000-00008.
Barlow J. Maternal representations in pregnancy: importance of the mothers’ relationship with their unborn babies. In: Leach P, editor. Transforming infant wellbeing: research, policy and practice for the first 1001 critical days. Abingdon; New York: Routledge; 2017. p. 37–46. https://doi.org/10.4324/9781315452890-5.
Salo S, Flykt M, Mäkelä J, Biringen Z, Kalland M, Pajulo M, Punamäki RL. The effectiveness of nurture- and play: a mentalization-based parenting group intervention for prenatally depressed mothers. Prim Health Care Res Dev. 2019. https://doi.org/10.1017/S1463423619000914An example of an RCT study using a pregnancy-specific intervention for high-risk mothers.
Hai AH, Hammock K, Velazquez MM. The efficacy of technology-based interventions for alcohol and illicit drug use among women of childbearing age: a systematic review and meta-Analysis. Alcohol Clin Exp Res. 2017. https://doi.org/10.1111/acer.14203.
Knaust T, Felnhofer A, Kothgassner OD, Höllmer H, Robert-Jacek G, Schulz H. Virtual trauma interventions for the treatment of post-traumatic stress disorders: a scoping review. Front Psychol. 2020. https://doi.org/10.3389/fpsyg.2020.562506A review on new, innovative virtually based interventions for trauma patients.
Dietz PM, Homa D, England LJ, Burley K, Tong VT, Dube SR, Bernert JT. Estimates of nondisclosure of cigarette smoking among pregnant and nonpregnant women of reproductive age in the united states. Am J Epidemiol. 2010. https://doi.org/10.1093/aje/kwq381.
Stone R. Pregnant women and substance use: fear, stigma, and barriers to care. Health Justice. 2015. https://doi.org/10.1186/s40352-015-0015-5.
Frazer Z, McConnell K, Jansson LM. Treatment for substance use disorders in pregnant women: motivators and barriers. Oxford: Elsevier Science Ltd; 2019. Provides understanding on the treatment barriers related to treatment of substance-using mothers.
Roberts SCM, Pies C. Complex calculations: how drug use during pregnancy becomes a barrier to prenatal care. Matern Child Health J. 2011. https://doi.org/10.1007/s10995-010-0594-7.
Heimdahl K, Karlsson P. Psychosocial interventions for substance-abusing parents and their young children: a scoping review. Addict Res Theory. 2016;24(1):236–47. https://doi.org/10.3109/16066359.2015.1118064.
McMahon TJ, Winkel JD, Suchman NE, Rounsaville BJ. Drug-abusing fathers: patterns of pair bonding, reproduction, and paternal involvement. J Subst Abuse Treat. 2007. https://doi.org/10.1016/j.jsat.2006.12.010.
Huizink AC. Prenatal maternal substance use and offspring outcomes: overview of recent findings and possible interventions. Eur Psychol. 2015. https://doi.org/10.1027/1016-9040/a000197.
Moreland AD, McRae-Clark A. Parenting outcomes of parenting interventions in integrated substance-use treatment programs: a systematic review. J Subst Abuse Treat. 2018. https://doi.org/10.1016/j.jsat.2018.03.005A relatively new systematic review related to integrated parenting interventions for substance-using mothers. Discusses issues on important multilevel components in these interventions.
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Flykt, M.S., Salo, S. & Pajulo, M. “A Window of Opportunity”: Parenting and Addiction in the Context of Pregnancy. Curr Addict Rep 8, 578–594 (2021). https://doi.org/10.1007/s40429-021-00394-4
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DOI: https://doi.org/10.1007/s40429-021-00394-4