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Correction to: Clinical Pharmacokinetics https://doi.org/10.1007/s40262-023-01215-9
In this article Figs. 1 and 2 were wrongly numbered; Fig. 1 should have been Fig. 2 and vice versa as shown below.
Geometric mean concentration time-profiles for glepaglutide. Vertical bars indicate 95% CIs; glepaglutide = parent + M1 + M2; normal renal function (eGFR ≥ 90 mL/min/1.73 m2); severe/ESRD: severe renal impairment (eGFR 15 to < 30 mL/min/1.73 m2) or end stage renal disease (eGFR < 15 mL/min/1.73 m2); parent: unmetabolized glepaglutide; M1: glepaglutide1–35; M2: glepaglutide1–34. CI confidence interval, eGFR estimated glomerular filtration rate, ESRD end-stage renal disease
Forest plots of Cmax and AUC0–168 h for glepaglutide. The primary pharmacokinetic endpoints (Cmax and AUC0–168 h) were log transformed and evaluated using an analysis of variance (ANOVA), with renal function as fixed effect. Ratios of geometric least-squares means (impaired renal function/normal renal function) and corresponding 90% confidence intervals (CIs) were estimated from the model. Glepaglutide = parent + M1 + M2; normal: normal renal function; severe/ESRD: severe renal impairment (eGFR 15 to < 30 mL/min/1.73 m2) or end stage renal disease (eGFR < 15 mL/min/1.73 m2); parent: unmetabolized glepaglutide; M1: glepaglutide1–35; M2: glepaglutide1–34. CI confidence interval, eGFR estimated glomerular filtration rate, ESRD end-stage renal disease
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Agersnap, M.A., Sonne, K., Knudsen, K.M. et al. Correction to: Pharmacokinetics, Safety, and Tolerability of Glepaglutide, a Long-Acting GLP-2 Analog, in Subjects with Renal Impairment. Clin Pharmacokinet 62, 653–654 (2023). https://doi.org/10.1007/s40262-023-01236-4
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DOI: https://doi.org/10.1007/s40262-023-01236-4