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Nutritional Implications in Postoperative Patients

  • Nutrition, Metabolism, and Surgery (Keith Miller, Section Editor)
  • Published:
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Abstract

Purpose of Review

In this review, the impact of surgical interventions along the gastrointestinal tract, from the stomach to the colon and rectum, on both immediate and long-term postoperative nutrition are reviewed.

Recent Findings

As the understanding of metabolic and cellular pathways continue to be elucidated, the recommendations for correction of nutritional deficits following surgery have continued to expand. Suggestions for nutritional monitoring and supplementation are provided from a wide variety of patient populations. The role of parenteral nutrition and enteral access for exogenous enteral feeding are also discussed in the context of holistic nutritional support.

Summary

Through examination of the anatomic changes that result following various operations, defined in this review via anatomic location, the differences in nutritional requirements of patients post operatively can be examined and implemented. Within the stomach, bariatric surgery has resulted in the reduction of metabolic disorders, but this anatomic rearrangement leads to further vitamin and mineral requirements that must be addressed. The same pattern is noted from the stomach to the colon, with varying physiologic and anatomical requirements. Understanding these physiologic derangements is an important component of post operative patient care.

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References

Papers of particular interest, published recently, have been highlighted as: •Of importance, ••Of major importance

  1. •• Jacobson R, Gurd EN, and Pimiento JM. Long-term nutrition alterations after surgery for gastrointestinal cancers. Nutr Clin Pract, 2023;38(4):721–730. This review was important in its detailing of operation specific nutritional morbidity as well as its emphasis on multidisiplinary approach to post operative nutrition.

  2. • Weimann A, et al. ESPEN practical guideline: Clinical nutrition in surgery. Clin Nutr, 2021;40(7):4745–4761. This was a helpful guideline that outlined key aspects of perioperative care including the re-establishment of enteral feeding post operatively as soon as feasible to minimize post operative complications.

  3. Sjöström L. Review of the key results from the Swedish Obese Subjects (SOS) trial - a prospective controlled intervention study of bariatric surgery. J Intern Med. 2013;273(3):219–34.

    Article  PubMed  Google Scholar 

  4. Bettini S, et al. Diet approach before and after bariatric surgery. Rev Endocr Metab Disord. 2020;21(3):297–306.

    Article  PubMed  PubMed Central  Google Scholar 

  5. •• Gasmi A, et al. Micronutrients deficiences in patients after bariatric surgery. Eur J Nutr, 2022;61(1):55–67. This review served as an important basis for the varying vitamin and mineral difficiencies, as well as their clinical outcomes, following different bariatric operations.

  6. Busetto L, et al. Practical recommendations of the obesity management task force of the European association for the study of obesity for the post-bariatric surgery medical management. Obes Facts. 2017;10(6):597–632.

    Article  PubMed  PubMed Central  Google Scholar 

  7. van Beek AP, et al. Dumping syndrome after esophageal, gastric or bariatric surgery: pathophysiology, diagnosis, and management. Obes Rev. 2017;18(1):68–85.

    Article  PubMed  Google Scholar 

  8. Tzovaras G, et al. Symptoms suggestive of dumping syndrome after provocation in patients after laparoscopic sleeve gastrectomy. Obes Surg. 2012;22(1):23–8.

    Article  PubMed  Google Scholar 

  9. Rogers C. Postgastrectomy nutrition. Nutr Clin Pract. 2011;26(2):126–36.

    Article  PubMed  Google Scholar 

  10. •• American Dietetic Association. Nutrition Care Manual®. https://www.nutritioncaremanual.org/topic.cfm?ncm_category_id=1&lv1=5522&lv2=19309&ncm_toc_id=19309&ncm_heading=Nutrition%20Care. The information within this dietary care manual was the foundation for many of our tables and figures and one of the sources for vitamin and nutritional deficits and their treatments. Accessed 1 Nov 2023.

  11. •• Oncology Nutrition for Clinical Practice, in Academy of Nutrition and Dietetics, W.V. Coble Voss A, Editor. 2021. pp. 375–395. This book chapter outlined evidence and experienced driven information for the detection and treatment of various deficiencies folling oncologic resections.

  12. Roberts G, et al. International Delphi consensus guidelines for follow-up after prophylactic total gastrectomy: the Life after Prophylactic Total Gastrectomy (LAP-TG) study. Gastric Cancer. 2022;25(6):1094–104.

    Article  PubMed  PubMed Central  Google Scholar 

  13. •• Petzel MQB, Ebrus CS, Nutrition in Pancreatic Cancer, in Pancreatic Cancer: A Multidisciplinary Approach MS, Bhutani, Katz MH, Maitra A, Herman JM, Wolff RA, editor. 2022, Springer, Cham. This book was a comprehensive review of pancreatic cancer, with a chapter delving into the specific requirements that pancreatic oncologic resections generate with emphasis on multidisciplinary cae in the perioperative setting.

  14. Institute of Medicine. Dietary Reference Intakes: The Essential Guide to Nutrient. Requirements. Washington: The National Academies Press; 2006.

    Google Scholar 

  15. Mechanick JI, et al. Clinical practice guidelines for the perioperative nutrition, metabolic, and nonsurgical support of patients undergoing bariatric procedures – 2019 update: Cosponsored by American Association of Clinical Endocrinologists/American College of Endocrinology, The Obesity Society, American Society for Metabolic & Bariatric Surgery, ObesityMedicine Association, and American Society of Anesthesiologists. Surg Obes Relat Dis. 2020;16(2):175–247.

    Article  PubMed  Google Scholar 

  16. Gianotti L, et al. Nutritional support and therapy in pancreatic surgery: A position paper of the International Study Group on Pancreatic Surgery (ISGPS). Surgery. 2018;164(5):1035–48.

    Article  PubMed  Google Scholar 

  17. Hüttner FJ, et al. Pylorus-preserving pancreaticoduodenectomy (pp Whipple) versus pancreaticoduodenectomy (classic Whipple) for surgical treatment of periampullary and pancreatic carcinoma. Cochrane Database Syst Rev. 2016;2(2):Cd006053.

  18. Petzel MQB, Hoffman L. Nutrition implications for long-term survivors of pancreatic cancer surgery. Nutr Clin Pract. 2017;32(5):588–98.

    Article  PubMed  Google Scholar 

  19. • Cañamares-Orbís P, García-Rayado G, Alfaro-Almajano E, Nutritional Support in Pancreatic Diseases. Nutrients. 2022;14(21). This review was an analysis of the main pancreatic diseases and dietary requirements, especially involving the use of pancreatic enzyme replacement and parenteral nutrition.

  20. Kim E, et al. Influence of preoperative nutritional status on clinical outcomes after pancreatoduodenectomy. HPB (Oxford). 2018;20(11):1051–61.

    Article  PubMed  Google Scholar 

  21. Whipple surgery nutrition therapy. Academy of Nutrition and Dietetics 2020. https://www.nutritioncaremanual.org/client_ed.cfm?ncm_client_ed_id=354.

  22. Hendifar AE, et al. Pancreas cancer-associated weight loss. Oncologist. 2019;24(5):691–701.

    Article  PubMed  Google Scholar 

  23. Armstrong T, et al. Pancreaticoduodenectomy for peri-ampullary neoplasia leads to specific micronutrient deficiencies. Pancreatology. 2007;7(1):37–44.

    Article  CAS  PubMed  Google Scholar 

  24. Gilliland TM, et al. Nutritional and metabolic derangements in pancreatic cancer and pancreatic resection. Nutrients. 2017;9(3).

  25. • Zackria RLR, Postcholecystectomy Syndrome. Treasure Island (FL): StatPearls Publishing, 2022. StatPearls [Internet]. This review outlined the various symptoms associated with postcholecystectomy syndrome including nausea and emesis timeframes, alterations in the gut microbiome and modifications in gastric motility.

  26. Moody FG, et al. Transduodenal sphincteroplasty with transampullary septectomy for stenosing papillitis. Am J Surg. 1991;161(2):213–8.

    Article  CAS  PubMed  Google Scholar 

  27. Arora D, et al. Post-cholecystectomy syndrome: A new look at an old problem. J Minim Access Surg. 2018;14(3):202–7.

    Article  PubMed  PubMed Central  Google Scholar 

  28. Altomare DF, Rotelli MT, Palasciano N. Diet After Cholecystectomy. Curr Med Chem. 2019;26(19):3662–5.

    Article  CAS  PubMed  Google Scholar 

  29. •• ASPEN core curriculum 3rd edition. p. 597. This curriculum model served as the basis for many of our charts and figures as well as recommendations for replenishing varying nutritional deficits following surgery.

  30. Dekaney CM, et al. Expansion of intestinal stem cells associated with long-term adaptation following ileocecal resection in mice. Am J Physiol Gastrointest Liver Physiol. 2007;293(5):G1013–22.

    Article  CAS  PubMed  Google Scholar 

  31. Rubin DC, Levin MS. Mechanisms of intestinal adaptation. Best Pract Res Clin Gastroenterol. 2016;30(2):237–48.

    Article  PubMed  PubMed Central  Google Scholar 

  32. Jeppesen PB. Teduglutide, a novel glucagon-like peptide 2 analog, in the treatment of patients with short bowel syndrome. Therap Adv Gastroenterol. 2012;5(3):159–71.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  33. • Ostomy Construction and Management: Personalizing the Stoma for the Patient, in Shackelford’s Surgery of the Alimentary Tract. p. 2147–2162. The book chapter listed gave a detailed outline of the major advances and protocols for stoma management in patients.

  34. • Hamdan M, and Puckett Y, Total Parenteral Nutrition, in StatPearls. 2023, StatPearls Publishing. Copyright © 2023, StatPearls Publishing LLC.: Treasure Island (FL). This overview of parenteral nutrition was important for the foundational understanding as well as indications for use.

  35. Matarese LE, Jeppesen PB, O’Keefe SJD. Short Bowel Syndrome in Adults. J Parenter Enter Nutr. 2014;38(1S):60S-64S.

    Article  Google Scholar 

  36. •• Amaro-Gahete FJ, et al. Multidisciplinary prehabilitation and postoperative rehabilitation for avoiding complications in patients undergoing resection of colon cancer: Rationale, Design, and methodology of the ONCOFIT study. Nutrients, 2022;14(21). ONCOFIT is a randomized, two arm clinical trial designed to detemine the influence of multidisciplinary perioperative program on post operative patients having undergone colon cancer resections with the conclusion that the program provides feaasibiliity, cost effectivness and improves health care outcomes in post operative patients.

  37. •• Bolton WS, et al. The incidence of low anterior resection syndrome as assessed in an international randomized controlled trial (MRC/NIHR ROLARR). Ann Surg, 2021;274(6):e1223-e1229. This article is based on an intenational retrospective cohort of patients undergoing low anterior resections within the ROLARR trial to determine the incidence and severity of the developemt of low anterior resection syndrome.

  38. Ribas Y, Muñoz-Duyos A. Conservative treatment of severe defecatory urgency and fecal incontinence: minor strategies with major impact. Tech Coloproctol. 2018;22(9):673–82.

    Article  PubMed  Google Scholar 

  39. • Hernandez MC, Wong P, Melstrom K. Low anterior resection syndrome. J Surg Oncol, 2023;127(8):1271–1276. This review provided our article with some foundational information on the symptoms and management of low anterior resection syndome.

  40. Paquette IM, et al. The American society of colon and rectal surgeons’ clinical practice guideline for the treatment of fecal incontinence. Dis Colon Rectum. 2015;58(7):623–36.

    Article  PubMed  Google Scholar 

  41. Phatak UR, et al. Impact of ileostomy-related complications on the multidisciplinary treatment of rectal cancer. Ann Surg Oncol. 2014;21(2):507–12.

    Article  PubMed  Google Scholar 

  42. Gamboa AC, et al. Implications of postoperative complications for survival after cytoreductive surgery and HIPEC: A multi-institutional analysis of the US HIPEC collaborative. Ann Surg Oncol. 2020;27(13):4980–95.

    Article  PubMed  PubMed Central  Google Scholar 

  43. Alyami M, et al. Ninety-day post-operative morbidity and mortality using the National Cancer Institute’s common terminology criteria for adverse events better describe post-operative outcome after cytoreductive surgery and hyperthermic intraperitoneal chemotherapy. Int J Hyperthermia. 2018;34(5):532–7.

    Article  PubMed  Google Scholar 

  44. •• Gearing PF, et al. Perioperative nutritional assessment and interventions in patients undergoing cytoreductive surgery and hyperthermic intraperitoneal chemotherapy (HIPEC): A systematic review. Eur J Surg Oncol, 2023;49(5):902–917. This systematic review pooled information on the benefits of nutritional assessment tools such as SGA and objective sarcopenia measures as well as examined optimization of post operative nutrition on clinical outcomes in patients who underwent HIPEC.

  45. Hübner M, et al. Guidelines for perioperative care in cytoreductive surgery (CRS) with or without hyperthermic IntraPEritoneal chemotherapy (HIPEC): Enhanced recovery after surgery (ERAS®) Society Recommendations - Part I: Preoperative and intraoperative management. Eur J Surg Oncol. 2020;46(12):2292–310.

    Article  PubMed  Google Scholar 

  46. Baratti D, et al. Early and long-term postoperative management following cytoreductive surgery and hyperthermic intraperitoneal chemotherapy. World J Gastrointest Oncol. 2010;2(1):36–43.

    Article  PubMed  PubMed Central  Google Scholar 

  47. Weimann A, et al. ESPEN guideline: Clinical nutrition in surgery. Clin Nutr. 2017;36(3):623–50.

    Article  PubMed  Google Scholar 

  48. Dineen SP, et al. Feeding tube placement during cytoreductive surgery and heated intraperitoneal chemotherapy does not improve postoperative nutrition and is associated with longer length of stay and higher readmission rates. J Surg Res. 2016;200(1):158–63.

    Article  PubMed  Google Scholar 

  49. • Fugazza, A., et al., Percutaneous endoscopic gastrostomy and jejunostomy: Indications and techniques. World J Gastrointest Endosc. 2022;14(5):250–266. This review served as a resource for explanations of gastrostomy and jejunostomy tubes as well as indications for placement and use.

  50. • Ley D, et al. Tutorial on adult enteral tube feeding: Indications, placement, removal, complications, and ethics. JPEN J Parenter Enteral Nutr, 2023;47(5):677–685. This review offered a broad overview of important aspects of enteral feeding care for clinicians to think about in patients requiring gastrostomy and jejunostomy feeding tiibe placement.

  51. Lobo DN, et al. Perioperative nutrition: Recommendations from the ESPEN expert group. Clin Nutr. 2020;39(11):3211–27.

    Article  CAS  PubMed  Google Scholar 

  52. McClave SA, et al. Guidelines for the provision and assessment of nutrition support therapy in the adult critically Ill patient: Society of Critical Care Medicine (SCCM) and American Society for Parenteral and Enteral Nutrition (A.S.P.E.N.). JPEN J Parenter Enteral Nutr. 2016;40(2):159–211.

    Article  CAS  PubMed  Google Scholar 

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AJ, KR, and KM wrote the main manuscript text and prepared the tables NB critically edited the manuscript All authors reviewed the manuscript

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Correspondence to Neal Bhutiani.

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Jones, A.N., Robinson, K.A., Munder, K. et al. Nutritional Implications in Postoperative Patients. Curr Surg Rep (2024). https://doi.org/10.1007/s40137-024-00404-0

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