Abstract
Cadmium oxide (CdO) had long been investigated for decades as prototypical wide-band-gap transparent conducting oxides (TCOs) possessing excellent n-type ability having its implications in the field of photo electronics. Despite this, there exists an uncertainty on the toxicity of CdO content during the synthesis and product retrieval which limits their use in biological applications. In this context, an approach to enhance the inbuilt properties of CdO particles by the means of loading (in coating form) with gold (Au) nanoparticles (NPs) to generate Au@CdO nanoconstructs (NCs) has been reported. Thus, formed Au@CdO NCs have been characterized by various spectroscopic and electron microscopic analysis for the structural, optical, and biological properties. For example, the UV–Vis spectroscopy revealed a typical λmax of CdO at 302 nm, and for the Au@CdO, a shift toward 496 nm was observed. The diffraction pattern demonstrated the crystalline phase corresponding to (1 1 1) plane with mean grain sizes of 24.9 and 30.6 nm for the CdO and Au@CdO, respectively. The FTIR and optical studies highlighted the intermolecular bonding with an increased bandgap confirming the efficient coating of Au onto CdO. The FESEM demonstrated spherical-to-elliptical-shaped anisotropic particles following the coating of CdO with Au and the grain size getting increased from 30 to 42 nm. On testing of the photocatalytic activity, we found that the Au@CdO NCs efficiently degraded the Rhodamine B dye (96% in 180 min) following the irradiation under artificial UV light. Furthermore, the Au@CdO NCs showed a significant antimicrobial effect at 80 μg/mL associated with a decline in the cell count. Alongside, the IC50 of Au@CdO against A549 and PBMC cells was fixed at 46.87 and 55.14 μg/mL, respectively. Such multifaceted Au@CdO NCs possessing optical properties might present themselves as the potential candidates for the extended photocatalytic and biomedical applications.
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Rohela, G.K., Srinivasulu, Y., Rathore, M.S.: A review paper on recent trends in bio-nanotechnology: implications and potentials. Nanosci. Nanotechnol. Asia 9, 12 (2019)
Samer, B., Muhammad, A., Tiziano, T., Marco, C., Flavio, R.: The history of nanoscience and nanotechnology: from chemical–physical applications to nanomedicine. Molecules 25, 112 (2020)
Rahman, G., Najaf, Z., Mehmood, A., Bilal, S., Shah, A.H.A., Mian, S.A., Ali, G.: An overview of the recent progress in the synthesis and applications of carbon nanotubes. Carbon 5, 3 (2019)
Muhammad, A.A.M.A., Nur Hawa, N.A., Shalini, K., Yusran, S.: Review of the use of transition-metal-oxide and conducting polymer-based fibres for high-performance supercapacitors. Mater. Des. 186, 108199 (2020)
Wang, Z., Chen, C., Wu, K., Chong, H., Ye, H.: Transparent conductive oxides and their applications in near infrared plasmonics. Phys. Status Solidi A 216, 1700794 (2019)
Afre, R.A., Sharma, N., Sharon, M., Sharon, M.: Transparent conducting oxide films for various applications: a review. Rev. Adv. Mater. Sci. 53, 79–89 (2018)
Vidhya, M., Pandi, P.R., Archana, R., Sadayandi, K., et al.: Comparison of sunlight-driven photocatalytic activity of semiconductor metal oxides of tin oxide and cadmium oxide nanoparticles. Optik 217, 164878 (2020)
Helen, S.J., Devadason, S., Haris, M., Mahalingam, T.: Transparent conducting Mo-doped CdO thin films by spray pyrolysis method for solar cell applications. J. Electron. Mater. 47, 2439–2446 (2018)
Mosquera, E., Pozo, I., Morelm, M.: Structure and red shift of optical band gap in CdO–ZnO nanocomposite synthesized by the sol gel method. J. Solid State Chem. 206, 265–271 (2013)
Thema, F.T., Beukes, P., Gurib-Fakim, A., Maaza, M.: Green synthesis of monteponite CdO nanoparticles by Agathosma betulina natural extract. J. Alloy Comp. 646, 1043–1048 (2015)
Mostafa, A.M., Mwafy, E.A.: Laser-assisted for preparation Ag/CdO nanocomposite thin film: structural and optical study. Opt. Mater. 107, 110124 (2020)
Mwafy, E.A., Hasanin, M.S., Mostafa, A.M.: Cadmium oxide/TEMPO-oxidized cellulose nanocomposites produced by pulsed laser ablation in liquid environment: synthesis, characterization, and antimicrobial activity. Opt. Laser Technol. 120, 105744 (2019)
Madeeha, N., Faiza, Z.G., Saad, H., Abdul, M., Sania, N., Joham, S.A., Muhammad, Z.: Green and chemical syntheses of CdO NPs: a comparative study for yield attributes, biological characteristics, and toxicity concerns. ACS Omega 5, 5739–5747 (2020)
Mostafa, A.M., Mwafy, E.A.: Synthesis of ZnO/CdO thin film for catalytic degradation of 4-nitrophenol. J. Mol. Struct. 1221, 128872 (2020)
Balmuri, S.R., Selvaraj, U., Kumar, V.V., Anthony, S.P., et al.: Effect of surfactant in mitigating cadmium oxide nanoparticle toxicity: implications for mitigating cadmium toxicity in environment. Environ. Res. 152, 141–149 (2017)
Brust, M., Bethell, D., Kiely, C.J., Schiffen, D.J.: Self-assembled gold nanoparticle thin films with non-metallic optical and electronic properties. Langmuir 14, 5425–5429 (1998)
Yousufi, M.K.: To study antibacterial activity of allium sativum, zingiber officinale and allium cepa by Kirby-Bauer method. J. Pharm. Biol. Sci. 4, 6–8 (2012)
Kumar, R.S., Almansour, A.I., Arumugam, N., Mohammad, F.: Design, synthesis and in vitro mechanistic investigation of novel hexacyclic cage-like hybrid heterocycles. Molecules 24, 3820 (2019)
Mostafa, A.M., Yousef, S.A., Eisa, W.H., Ewaida, M.A., Al-Ashkar, E.A.: Au@CdO core/shell nanoparticles synthesized by pulsed laser ablation in Au precursor solution. Appl. Phys. A 123, 774 (2017)
Gültekin, A., Karanfil, G., Özel, F., Kus, M., Say, R., Sönmezoğlu, S.: Synthesis and characterisations of Au-nanoparticle-doped TiO2 and CdO thin films. J. Phys. Chem. Solids 75, 775–781 (2014)
Kose, S., Atay, F., Bilgin, V., Akyuz, I.: In doped CdO films: electrical, optical, structural and surface properties. Int. J. Hydrog. Energy 34, 5260–5266 (2009)
Shannon, R.D.: Revised effective ionic radii and systematic studies of interatomic distances in halides and chalcogenides. Acta Crystallogr. Sect. A Cryst. Phys. Diffr. Theor. Gen. Crystallogr. 32, 751–767 (1976)
Kaviyarasu, K., Manikandan, E., Paulraj, P., Mohamed, S.B., Kennedy, J.: One dimensional well-aligned CdO nanocrystal by solvothermal method. J. Alloy Compd. 593, 67–70 (2014)
Sivakumar, S., Venkatesan, A., Soundhirarajan, P., Khatiwada, C.P.: Synthesis, characterizations and anti-bacterial activities of pure and Ag doped CdO nanoparticles by chemical precipitation method. Spectrochim. Acta A 136, 1751–1759 (2015)
Solati, E., Mashayekh, M., Dorranian, D.: Effects of laser pulse wavelength and laser fluence on the characteristics of silver nanoparticle generated by laser ablation. Appl. Phys. A Mater. Sci. Process 112, 689–694 (2013)
Janani, B., Gayathri, G., Syed, A., Raju, L.L., Marraiki, N., Elgorban, A.M., Khan, S.S.: The effect of various capping agents on surface modifications of CdO NPs and the investigation of photocatalytic performance, antibacterial and anti-biofilm activities. J. Inorg. Organomet. Polym. 30, 1865–1876 (2020)
Salehi, B., Mehrabian, S., Ahmadi, M.: Investigation of antibacterial effect of Cadmium oxide nanoparticles on Staphylococcus aureus bacteria. J. Nanobiotechnol. 12, 26 (2014)
Salehi, B., Mortaz, E., Tabarsi, P.: Comparison of antibacterial activities of cadmium oxide nanoparticles against Pseudomonas aeruginosa and Staphylococcus aureus bacteria. Adv. Biomed. Res. 4, 105 (2015)
Juneja, S., Madhavan, A.A., Ghosal, A., Moulick, R.G., Bhattacharya, J.: Synthesis of graphenized Au/ZnO plasmonic nanocomposites for simultaneous sunlight mediated photo-catalysis and anti-microbial activity. J. Hazard. Mater. 347, 378–389 (2018)
Kumar, P., Mathpal, M.C., Prakash, J., Viljoen, B.C., Roos, W.D., Swart, H.C.: Band gap tailoring of cauliflower-shaped CuO nanostructures by Zn doping for antibacterial applications. J. Alloys Comp. 832, 154968 (2020)
Kumar, P., Mathpal, M.C., Inwati, G.K., Ghosh, S., Kumar, V., Roos, W.D., Swart, H.C.: Optical and surface properties of Zn doped CdO nanorods and antimicrobial applications. Colloids Surf. A 605, 125369 (2020)
Kaviyarasu, K., Kanimozhi, K., Matinise, N., et al.: Antiproliferative effects on human lung cell lines A549 activity of cadmium selenide nanoparticles extracted from cytotoxic effects: investigation of bio-electronic application. Mater. Sci. Eng. C 76, 1012–1025 (2017)
Demir, E., Qin, T., Li, Y., Zhang, Y., et al.: Cytotoxicity and genotoxicity of cadmium oxide nanoparticles evaluated using in vitro assays. Mutat. Res.-Gen. Tox. Environ. 850–851, 503149 (2020)
Shad, N.A., Sajid, M.M., Ul Haq, A., et al.: Photocatalytic investigation of cadmium oxide nanosheets prepared by hydrothermal method. Arab. J. Sci. Eng. 44, 6669–6675 (2019)
Somasundaram, G., Rajan, J., Sangaiya, P., Dilip, R.: Hydrothermal synthesis of CdO nanoparticles for photocatalytic and antimicrobial activities. Result Mater. 4, 100044 (2019)
Menazea, A., Alashkar, E.: Impact of CuO doping on the properties of CdO thin films on the catalytic degradation by using pulsed-Laser deposition technique. Opt. Mater. 100, 109663 (2020)
Saha, M., Ghosh, S., De, S.K.: Nanoscale Kirkendall effect driven Au decorated CdS/CdO colloidal nanocomposites for efficient hydrogen evolution, photocatalytic dye degradation and Cr(VI) reduction. Cat. Today. 340, 253–267 (2020)
Kumar, P., Kumar, A., Rizvi, M.A., Moosvi, S.K., et al.: Surface, optical and photocatalytic properties of Rb doped ZnO nanoparticles. Appl. Surf. Sci. 514, 145930 (2020)
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The authors would like to acknowledge the financial support provided by a Research University Grant from University of Malaya (RU001-2020). The KSU authors are grateful to the Deanship of Scientific Research, King Saud University for funding through Vice Deanship of Scientific Research Chairs.
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Sagadevan, S., Vennila, S., Muthukrishnan, L. et al. Facile fabrication of Au-loaded CdO nanoconstructs with tuned properties for photocatalytic and biomedical applications. J Nanostruct Chem 11, 561–572 (2021). https://doi.org/10.1007/s40097-020-00384-4
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DOI: https://doi.org/10.1007/s40097-020-00384-4