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N-formylation of amine using graphene oxide as a sole recyclable metal-free carbocatalyst

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Abstract

Graphene oxide (GO), an inexpensive, environment-friendly, and metal-free carbocatalyst, used for the N-formylation of amines is developed. In this reaction, GO shows good activity, selectivity, and recyclability. This strategy has an array of advantages, such as being metal free, without additive, wide-scope protocol, scalable with a low catalyst loading of 3 wt%, use of readily available and recyclable carbocatalyst, and DMF as a readily available formyl source. Furthermore, this strategy provides an avenue for the convenient hydroformylation of various amines.

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Acknowledgements

We are grateful to the National Natural Science Foundation of China (No. 21402168), Scientific Research Foundation of Hunan Provincial Education Department (No. 15B232), National Natural Science Foundation of Hunan Province (No. 2018JJ2389), and Hunan 2011 Collaborative Innovation Center of Chemical Engineering & Technology with Environmental Benignity and Effective Resource Utilization for their support of our research.

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Authors and Affiliations

  1. The Key Laboratory for Green Organic Synthesis and Application of Hunan Province, Xiangtan University, Xiangtan, 411105, China

    Juan Ma, Jingyu Zhang, Xiao Zhou, Jiawei Wang & Hang Gong

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  1. Juan Ma
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  2. Jingyu Zhang
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  3. Xiao Zhou
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  5. Hang Gong
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Correspondence to Hang Gong.

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Ma, J., Zhang, J., Zhou, X. et al. N-formylation of amine using graphene oxide as a sole recyclable metal-free carbocatalyst. J IRAN CHEM SOC 15, 2851–2860 (2018). https://doi.org/10.1007/s13738-018-1471-3

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