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Synthesis and structure elucidation of some new azo dye from hydroxyquinolin-2(1H)-one derivatives and their antimicrobial evaluation

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Abstract

The aim of the work is synthesis of some novel azo dye from 1,2-dihydro-4-hydroxy-2-oxoquinoline-6-sulfonic acid (3), 4-hydroxy-6-methoxyquinolin-2(1H)-one (4), and 4-hydroxy-6-nitroquinolin-2(1H)-one (5). The prepared compounds were screened for antibacterial against Staphylococcus aureus, Escherichia coli, and antifungal activity against Candida sp., Aspergillus multi and Aspergillus niger. The structure of newly compounds was characterized by 1H-NMR, IR and elemental analysis.

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Acknowledgements

The author is thankful to College of Science, Jouf University, Sakaka, Kingdom of Saudi and Chemistry Department, Faculty of Science, Zagazig University, Zagazig, Egypt and Organometallic and organometalloid department, National Research Centre, Dokki, Egypt.

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Authors and Affiliations

  1. Chemistry Department, College of Science, Jouf University, P. O. Box 72341, Sakaka, Aljouf, Kingdom of Saudi Arabia

    Amira A. Ghoneim

  2. Chemistry Department, Faculty of Science, Zagazig University, Zagazig, Egypt

    Amira A. Ghoneim

  3. Organometallic and Organometalloid Chemistry Department, National Research Centre, Dokki, Cairo, Egypt

    Nesrin M. Morsy

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  1. Amira A. Ghoneim
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  2. Nesrin M. Morsy
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Correspondence to Amira A. Ghoneim.

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Ghoneim, A.A., Morsy, N.M. Synthesis and structure elucidation of some new azo dye from hydroxyquinolin-2(1H)-one derivatives and their antimicrobial evaluation. J IRAN CHEM SOC 15, 2567–2572 (2018). https://doi.org/10.1007/s13738-018-1445-5

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  • DOI: https://doi.org/10.1007/s13738-018-1445-5

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