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A facile and effective procedure for synthesis of polyfunctionalized pyrrolines from simultaneously stirring of carbon disulfide, aniline, arylglyoxals and β-enaminocarbonyls

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Abstract

An efficient one-pot synthesis of 2H-pyrroline derivatives by a four-component reaction between carbon disulfide, aniline, arylglyoxals and β-enaminocarbonyls in acetonitrile at room temperature under mild reaction conditions is reported. The addition reaction has been done to access broad range of 5-hydroxy-4-phenylcarbamodithioate 2-H pyrroline derivatives after about 6 h stirring. All reactions were performed in acetonitrile at room temperature. Reactions are clean, and products were isolated by simple filtration.

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Acknowledgements

We gratefully acknowledge, Islamic Azad University, Rafsanjan branch for financial support.

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Authors and Affiliations

  1. Young Researchers and Elite Club, Rafsanjan Branch, Islamic Azad University, Rafsanjan, Iran

    Mozhgan Masoudi & Alireza Maleki

  2. Department of Chemistry, Vali-e-Asr University, Rafsanjan, 77176, Iran

    Mohammad Anary-Abbasinejad

Authors
  1. Mozhgan Masoudi
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  2. Mohammad Anary-Abbasinejad
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  3. Alireza Maleki
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Correspondence to Mozhgan Masoudi.

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Masoudi, M., Anary-Abbasinejad, M. & Maleki, A. A facile and effective procedure for synthesis of polyfunctionalized pyrrolines from simultaneously stirring of carbon disulfide, aniline, arylglyoxals and β-enaminocarbonyls. J IRAN CHEM SOC 14, 2299–2304 (2017). https://doi.org/10.1007/s13738-017-1166-1

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  • DOI: https://doi.org/10.1007/s13738-017-1166-1

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