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A novel one-pot isocyanide-based three-component reaction: synthesis of highly functionalized imidazo-chromen-4-ones

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Abstract

A novel approach has been developed for the efficient synthesis of structurally diverse imidazo-chromen-4-ones via a three-component condensation reaction of 2-aminoazines and various isocyanides with 4-oxo-4H-chromene-3-carbaldehyde derivatives in the presence of p-TSOH/ZnCl2 as the catalyst in methanol under reflux conditions for 48 h.

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Acknowledgments

We gratefully acknowledge financial supports from the Research Council of Shahid Beheshti University and Iran National Science Foundation (INSF).

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Authors and Affiliations

  1. Department of Chemistry, Shahid Beheshti University, G. C., P. O. Box 19396-4716, Tehran, Iran

    Sajjad Keshipour, Ahmad Shaabani, Salman Shojaei & Hamed Nosrati

  2. Department of Chemistry, University of Malaya, 50603, Kuala Lumpur, Malaysia

    Seik Weng Ng

Authors
  1. Sajjad Keshipour
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  2. Ahmad Shaabani
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  3. Salman Shojaei
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  4. Hamed Nosrati
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  5. Seik Weng Ng
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Correspondence to Ahmad Shaabani.

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Keshipour, S., Shaabani, A., Shojaei, S. et al. A novel one-pot isocyanide-based three-component reaction: synthesis of highly functionalized imidazo-chromen-4-ones. J IRAN CHEM SOC 12, 1655–1663 (2015). https://doi.org/10.1007/s13738-015-0640-x

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  • DOI: https://doi.org/10.1007/s13738-015-0640-x

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