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Synthesis of cinacalcet containing acrylamide hydrogels by photopolymerization and studying their sensing properties

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Abstract

Novel cinacalcet containing acrylamide hydrogel (CIN-gel) was fabricated by free radical photopolymerization of acrylamide/N,N’-methylenebisacrylamide with cinacalcet hydrochloride as a photoinitiator. This hydrogel prepared by a one-pot photo-induced polymerization system was characterized with respect to its morphological and fluorescence features by means of SEM, UV–vis, and fluorescence spectroscopy. The CIN-gel displayed dual fluorescence emission when excited at 250 nm in water:acetonitrile (1:1, w/w) solution system owing to twisted intramolecular charge transfer between naphthalene and dimethylamino units in the cinacalcet moiety. The prepared fluorophore containing CIN-gel was employed as a fluorescent probe towards certain specific heavy metal ions (HMIs) such as Pb2+, Sn2+, Zn2+ and nitroaromatic compounds (NACs) such as 2-nitrotoluene, 2,4-dinitrophenol, 1,2-dinitrobenzene, 2,4,6-trinitrotoluene, 2,4,6-trinitrophenol, 4-nitrophenol, and 2,4-dinitrophenol. The use of cinacalcet hydrochloride as a photoinitiator and analyte for measuring HMIs and NACs during the production of the hydrogel is being reported for the first time. Fluorescence intensity of CIN-gel was gradually reduced upon the addition of NACs and HMIs. For all compounds, the highest quenching efficiencies were attained in the presence of Zn2+ (35.93%), 2,4,6-trinitrotoluene (95.67%), and 2,4-dinitrophenol (94.96%). Because of its simplicity and sensitivity, the proposed CIN-gel can be considered as potential chemical probe to detect the HMIs ions and NACs compounds.

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Acknowledgements

Financial support for this study obtained from the Scientific Research Projects Unit of Kocaeli University of Grant KOU-2018-50HD is gratefully acknowledged.

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Authors and Affiliations

  1. Department of Chemistry and Chemical Processing Tech., Kocaeli University, 41140, Kocaeli, Turkey

    Erdinc Doganci

  2. Department of Chemistry, Gebze Technical University, 41400, Kocaeli, Turkey

    Mustafa Uygun

  3. Department of Polymer Engineering, Faculty of Engineering, Yalova University, 77100, Yalova, Turkey

    Mehmet Atilla Tasdelen

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  1. Erdinc Doganci
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  2. Mustafa Uygun
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  3. Mehmet Atilla Tasdelen
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Correspondence to Erdinc Doganci or Mehmet Atilla Tasdelen.

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Doganci, E., Uygun, M. & Tasdelen, M.A. Synthesis of cinacalcet containing acrylamide hydrogels by photopolymerization and studying their sensing properties. Iran Polym J 32, 1359–1366 (2023). https://doi.org/10.1007/s13726-023-01200-w

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  • DOI: https://doi.org/10.1007/s13726-023-01200-w

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