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Preparation and evaluation of chiral selective cation-exchange PMMA–PNIPAm thermal-sensitive membranes

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Abstract

Selective cation-exchange membranes are placing a key role in separation processes. The application of selective cation-exchange membranes is wide since there are many kinds of mixtures needed to be separated for reuse. In this study, a facile and efficient one-pot approach was used to obtain monodispersed methyl methacrylate–N-isopropyl acrylamide (MMA–NIPAm) polymer by atom transfer radical precipitation polymerization (ATRPP) and then MMA–NIPAm chiral selective separation membranes were prepared for separating racemic equol. Firstly, using dodecylbenzenesulfonyl chloride (DBSC) as the initiator, bipyridine (bipy)/CuCl as the catalyst system, acetonitrile as the solvent, and S-equol as template molecule by which a MMA–NIPAm copolymer was synthesized and it was characterized by TEM, FTIR, TGA, UV–vis absorption spectrum, and dynamic layer scattering analysis. Lastly, MMA–NIPAm chiral separation membranes were prepared by casting 3 wt% of MMA–NIPAm copolymer dimethyl formamide (DMF) solution on a rimmed glass plate and evaporated the solvent completely at 100 °C under vacuum. Then, the PMMA–PNIPAm chiral selective cation-exchange membranes were prepared by immersing in methanol/acetic acid (95:5, v/v) to remove the template molecules. Most worthy of mention was that the prepared chiral selective separation membranes could separate S-equol and R-equol from the mixture of racemic equol. In application of a thermo-responsive monomer, the separation ability of the prepared PMMA–PNIPAm chiral separation membranes could be tunable according to environment temperature changes.

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Acknowledgments

This work was financially supported by Foundation of State Key Laboratory of Natural and Biomimetic Drugs (K20110105).

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Authors and Affiliations

  1. School of Biotechnology and Chemical Engineering, Ningbo Institute of Technology, Zhejiang University, Ningbo, 315100, People’s Republic of China

    Yinlin Lei, Fei Chen Dr. & Yunjie Luo

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  1. Yinlin Lei
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  2. Fei Chen Dr.
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  3. Yunjie Luo
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Correspondence to Fei Chen Dr..

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Lei, Y., Chen, F. & Luo, Y. Preparation and evaluation of chiral selective cation-exchange PMMA–PNIPAm thermal-sensitive membranes. Iran Polym J 23, 679–687 (2014). https://doi.org/10.1007/s13726-014-0262-7

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  • DOI: https://doi.org/10.1007/s13726-014-0262-7

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