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Multidisciplinary treatment for locally advanced breast cancer with internal mammary lymph node metastasis in an elderly patient

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A Correction to this article was published on 03 September 2019

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Abstract

Internal mammary lymph node (IMLN) metastasis is one of the important prognostic indicators in breast cancer. However, the management for IMLN metastasis is not established. The dissection for IMLN metastasis is not recommended in the National Comprehensive Cancer Network guidelines version3. 2015. Furthermore, radiotherapy including IMLN region and biopsy have attendant risks and hence should be performed with caution. Here, we describe our experience of multidisciplinary treatment for locally advanced breast cancer with IMLN metastasis in an elderly patient. Core-needle biopsy of the breast tumor histologically diagnosed the tumor as estrogen receptor positive, progesterone receptor positive, human epidermal growth factor receptor-2 negative, and high Ki-67 labeling index. IMLN swelling was detected by ultrasonography and breast cancer metastasis was diagnosed by fine-needle aspiration cytology. The patient underwent mastectomy and axillary lymph node dissection, followed by postmastectomy radiation therapy. Systemic therapy using tegafur plus uracil (UFT®; Taiho Pharmaceutical Co., Ltd, Tokyo, Japan) and letrozole was beneficial treatment for disease control.

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Change history

  • 03 September 2019

    In the original publication, in Table 1, the patient 3, 58 years of age, was scheduled to be administered eribulin after gemcitabine as adjuvant therapy.

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Author information

Authors and Affiliations

  1. Department of Breast Surgery, Shiga General Hospital, 5-4-30, Moriyama-shi, Moriyama, Shiga, 524-8524, Japan

    Haruko Takuwa, Wakako Tsuji & Fumiaki Yotsumoto

  2. Department of Pathology, Shiga General Hospital, Moriyama, Shiga, Japan

    Yoshihiro Yamamoto

  3. Department of Radiation Oncology, Shiga General Hospital, Moriyama, Shiga, Japan

    Chikako Yamauchi

Authors
  1. Haruko Takuwa
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  2. Wakako Tsuji
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  3. Yoshihiro Yamamoto
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  4. Chikako Yamauchi
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  5. Fumiaki Yotsumoto
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Corresponding author

Correspondence to Haruko Takuwa.

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Conflict of interest

No conflicts of interest relevant to this article are reported.

Ethical approval

All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional and/or national research committee and with the Helsinki Declaration and its later amendments or comparable ethical standards.

Informed consent

Informed consent was obtained from the patient in this study.

Additional information

This report is based on the poster presentation in the 55th Annual Meeting of Japan Society of Clinical Oncology: P4–6.

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Takuwa, H., Tsuji, W., Yamamoto, Y. et al. Multidisciplinary treatment for locally advanced breast cancer with internal mammary lymph node metastasis in an elderly patient. Int Canc Conf J 8, 1–6 (2019). https://doi.org/10.1007/s13691-018-0344-z

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  • DOI: https://doi.org/10.1007/s13691-018-0344-z

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