Abstract
Four new ent-kaurane diterpenoids, namely, 3α-tigloyloxypterokaurene L3 (1), ent-17-hydroxy-kaura-9(11),15-dien-19-oic acid (2), and wedelobatins A (3) and B (4), together with 11 known ent-kaurane diterpenoids (5-15), were isolated from the ethanol extract of Wedelia trilobata. All the structures of 1–15 were elucidated on the basis of spectroscopic studies.
Article PDF
Similar content being viewed by others
Avoid common mistakes on your manuscript.
References
That, Q. T.; Jossang, J.; Jossang, A.; Kim, P. P. N.; Jaureguiberry, G. J. Org. Chem.2007, 72, 7102–7105.
Balekar, N.; Nakpheng, T.; Katkam N. G.; Srichana, T. Phytomedicine2012, 19, 1178–1184.
Bohlmann, F.; Ziesche, J.; King, R. M.; Robinson, H. Phytochemistry1981, 20, 751–756.
Vieira, H. S.; Takahashi, J. A.; Boaventura, M. A. D. Fitoterapia2001, 72, 854–856.
Qiang, Y.; Du, D. L.; Chen, Y. J.; Gao, K. Helv. Chim. Acta2011, 94, 817–823.
Roynolds, W. F.; Enríquez, R. G.; Escobar, L. I.; Lozoya, X. Can. J. Chem.1984, 62, 2421–2425.
Hutchison, M.; Lewer, P.; MacMillan, J. J. Chem. Soc., Perkin Trans. 11984, 10, 2363–2366.
Morris, B. D.; Charlet, L. D.; Foster, S. P. J. Chem. Ecol.2009, 35, 50–57.
Jung, H. A.; Lee, E. J.; Kim, J. S.; Kang, S. S.; Lee, J. H.; Min, B. S.; Choi, J. S. Arch. Pharm. Res.2009, 32, 1399–1408.
Ragasa, C. Y.; Padolina, W. G.; Bowden, B. F.; Li, S. X.; Tapiolas, D. M.; Coll, J. C. J. Nat. Prod.1993, 56, 386–393.
Ahmed, M.; Jakupovic, J.; Castro, V. Phytochemistry, 1991, 30, 1712–1714.
Silva, E. A.; Takahashi, J. A.; Boaventura, M. A. D.; Oliveira, A. B. Phytochemistry1999, 52, 397–400.
Li, C.; Lee, D.; Graf, T. N.; Phifer, S. S.; Nakanishi, Y.; Riswan, S.; Setyowati, F. M.; Saribi, A. M.; Soejarto, D. D.; Farnsworth, N. R.; Falkinham III, J. O.; Kroll, D. J.; Kinghorn, A. D.; Wani, M. C.; Oberlies, N. H. J. Nat. Prod.2009, 72, 1949–1953.
Santos, H. S.; Barros, F. W. A.; Albuquerque, M. R. J. R.; Bandeira, P. N.; Pessoa, C.; Braz-Filho, R.; Monte, F. J. Q.; Leal-Cardoso, J. H.; Lemos, T. L. G. J. Nat. Prod.2009, 72, 1884-1887.
Cuenca, M. D. R.; Catalan, C. A. N.; Díaz, J. G.; Herz, W. J. Nat. Prod.1991, 54, 1162–1164.
Wu, M. L.; Zhang, D. Z.; Xu, Q. J.; Xie, R. R.; Li, Q. Q. Zhongcaoyao2010, 41, 681–685.
Author information
Authors and Affiliations
Corresponding author
Additional information
This article is published with open access at Springerlink.com
Electronic supplementary material
Rights and permissions
Open Access This article is distributed under the terms of the Creative Commons Attribution 2.0 International License (https://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
About this article
Cite this article
Ma, BJ., Wen, CN., Gao, Y. et al. ent-Kaurane diterpenoids from the plant Wedelia trilobata. Nat. Prod. Bioprospect. 3, 107–111 (2013). https://doi.org/10.1007/s13659-013-0029-4
Received:
Accepted:
Published:
Issue Date:
DOI: https://doi.org/10.1007/s13659-013-0029-4