Abstract
The genus Empetrum (family: Empetraceae) represents an abundant source of biologically active compounds with wide range of pharmacological effects. Empetrum species are widespread throughout the Northern hemisphere and extensively used in traditional medicine. Although biological effects of these plants have been studying for decades, recent analytical methods along with in vivo experiments provide new data on chemical compounds extracted from the species and their biological activities. This review focuses on phytochemistry, pharmacology and known biological effects of chemical compounds extracted from genus Empetrum to explore their therapeutic potential, particularly in seizure and other neurological disorders and includes an overview of scientific literature concerning the genus Empetrum published between 1987 and 2021.
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This research was supported by RFBR according to the research Project No. 20-315-90015.
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EAB, substantially contributed to the conception and design of the article and interpreting the relevant literature. Drafted the article. EVE critically revised the article for important intellectual content. TVK substantially contributed to the conception and design of the article and interpreting the relevant literature. EAK critically revised the article for important intellectual content. KSB substantially contributed to the conception and design of the article and interpreting the relevant literature. Translation. AOP participated in drafting and critically revised the article for important intellectual content. VGL gave final approval of the version to be submitted. MVB gave final approval of the version to be submitted. All authors have read and agreed to the published version of the manuscript.
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Ekaterina A. Bezverkhniaia has no conflict of interest. Elena V. Ermilova has no conflict of interest. Tatyana V. Kadyrova has no conflict of interest. Efim A. Krasnov has no conflict of interest. Konstantin S. Brazovskii has no conflict of interest. Anastasiia O. Ponkratova has no conflict of interest. Vladimir G. Luzhanin has no conflict of interest. Mikhail V. Belousov has no conflict of interest.
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Bezverkhniaia, E.A., Ermilova, E.V., Kadyrova, T.V. et al. Phytochemistry, ethnopharmacology and pharmacology of the genus Empetrum: a review. ADV TRADIT MED (ADTM) 23, 659–672 (2023). https://doi.org/10.1007/s13596-021-00612-4
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DOI: https://doi.org/10.1007/s13596-021-00612-4