Abstract
Scabies is a neglected tropical disease that contributes greatly to global morbidity and mortality and it is responsible for a wide range of infections including impetigo, abscesses and cellulitis that can lead to serious complications such as septicemia, kidney disease and rheumatic heart disease. Scabies remains one of the commonest of skin diseases seen in developing countries. Although its distribution is subject to a cycle of infection, with peaks and troughs of disease prevalence, this periodicity is often less obvious in poor communities. The objective of this review was to collect available data about the therapy of scabies using medicinal plant so far studied by ethno botanical surveys in Ethiopia and gives comprehensive information on the name of plants, method of preparation, route of administration and plant part used. The Data was collected using the keywords “Traditional used medicinal plants for scabies therapy in Ethiopia” in searching the major databases including Web of Science, Scopus, Google Scholar, Science Direct, BioMed Central, PubMed and Springer link documenting published studies done on ethno botany of medicinal plants used in Ethiopia. Ethinobotanical data was analyzed with descriptive statistics and expressed in pie charts. The Review conducted 52 medicinal plants (39 families) recorded to treat scabies in Ethiopia. Parts of medicinal plants used analysis indicates leaves occupy the highest proportion (57%), followed by roots (12%) and others. Although Phytolacca dodecandra L’Herit was the most popular medicinal plant used for the treatment of scabies with the frequency of report six time (29%).
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References
Abdurhman N (2010) Ethnobotanical study of medicinal plants used by local people in Ofla Wereda, southern zone of Tigray Region. Addis Ababa University, Ethiopia
Abebe D, Hagos E (1991) In the traditional health practices of Ethiopia. In: Engles JMM, Hawkes JG, Worede M (eds) Plant genetic resources of Ethiopia. Cambridge University Press, p 101
Amenu E (2007) Use and management of medicinal plants by indigenous people of ejaji area (chelya woreda) West Shoa, Ethiopia. Addis Ababa: Addis Ababa University
Andarge E, Shonga A, Agize M, Tora A (2015) Utilization and conservation of medicinal plants and their associated indigenous knowledge (IK) in Dawuro Zone: an ethnobotanical approach. Int J Med Plant Res 4:330–337
Araya S, Abera B, Giday M (2015) Study of plants traditionally used in public and animal health management in Seharti Samre District, Southern Tigray, Ethiopia. J Ethnobiol Ethnomed 11(1):22
Arlian LG (1989) Biology, host relations, and epidemiology of Sarcoptes scabiei. Annu Rev Entomol 34(1):139–159
Arlian L, Vyszenski-Moher D, Pole M (1989) Survival of adults and developmental stages of Sarcoptesscabiei var. canis when off the host. Exp Appl Acarology 6(3):181–187
Atnafu H, Awas T, Alemu S, Wube S (2018) Ethnobotanical study of medicinal plants in selale mountain ridges, North Shoa, Ethiopia. Int J Biodivers 2(6):567–577
Burgess I (1994) Sarcoptes scabiei and scabies. Adv Parasit 33:235–292
Chakrabarti A (1985) Some epidemiological aspects of animal scabies in human population. Int J Zoonoses 12(1):39–52
Chekole G, Asfaw Z, Kelbessa E (2015) Ethnobotanical study of medicinal plants in the environs of Tara-gedam and Amba remnant forests of Libo Kemkem District, northwest Ethiopia. J Ethnobiol Ethnomed 11(1):4
Chosidow O (2006) Scabies. New England J Med 354(16):1718–1727
Currie BJ (1995) Ivermectin and crusted (Norwegian) scabies. Med J Australia 163:559–560
Dagne H, Dessie A, Destaw B, Yallew WW, Gizaw Z (2019) Prevalence and associated factors of scabies among schoolchildren in Dabat district, northwest Ethiopia, 2018. Environ Health Prev Med 24(1):67
Dalziel JM (1937) The useful plants of west tropical Africa. In: The useful plants of West Tropical Africa. Crown Agents for the Colonies, London
Dorsaz AC, Hostettmann K (1986) Further saponins from Phytolacca dodecandra L′ Herit. Helv Chim Acta 69(8):2038–2047
Enbiale W, Ayalew A (2018) Investigation of a scabies outbreak in drought-affected areas in Ethiopia. Trop Med Infect Dis 3(4):114
Engelman D, Cantey PT, Marks M, Solomon AW, Chang AY, Chosidow O et al (2019) The public health control of scabies: priorities for research and action. Lancet 394(10192):81–92
Enyew A, Asfaw Z, Kelbessa E, Nagappan R (2014) Ethnobotanical study of traditional medicinal plants in and around Fiche District, Central Ethiopia. Curr Res J Biol Sci 6(4):154–167
Fenetahun Y, Eshetu G, Worku A, Abdella T (2017) A survey on medicinal plants used by traditional healers in Harari regional State, East Ethiopia. J Med Plants Stud 5:85–90
Gabriel T, Guji T (2014) Ethnopharmacological survey of medicinal plants in Agaro district, Jimma zone, South West Ethiopia. IJPSR 5:3551–3559
Gedif T, Hahn H-J (2003) The use of medicinal plants in self-care in rural central Ethiopia. J Ethnopharmacol 87(2–3):155–161
Giday M, Ameni G (2003) An ethnobotanical survey of plants of veterinary importance in two woredas of southern Tigray, Northern Ethiopia. SINET Ethiop J Sci 26(2):123–136
Giday K, Lenaerts L, Gebrehiwot K, Yirga G, Verbist B, Muys B (2016) Ethnobotanical study of medicinal plants from degraded dry afromontane forest in northern Ethiopia: species, uses and conservation challenges. J Herb Med 6(2):96–104
Grynkiewicz G, Gadzikowska M (2008) Tropane alkaloids as medicinally useful natural products and their synthetic derivatives as new drugs. Pharmacol Rep 60(4):439
Hay R, Steer A, Engelman D, Walton S (2012) Scabies in the developing world—its prevalence, complications, and management. Clin Microbiol Infect 18(4):313–323
Health-Ethiopia, M. o. (October 11, 2019) Neglected tropical diseases (NTDs) program in Ethiopia. Retrieved from https://www.slideserve.com/banyan/community-health-initiatives-and-family-planning-in-snnp-of-ethiopia
Heukelbach J, Feldmeier H (2006) Scabies. Lancet 367(9524):1767–1774
Jackson R (2004) Scabies by Kenneth Mellanby. J Cutan Med Surg: Inc Med Surg Dermatol 8(2):73–76
Janzen JM (1981) The need for a taxonomy of health in the study of African therapeutics. Social Science & Medicine. Part B: Med Anthropol 15(3):185–194
Jima TT, Megersa M (2018) Ethnobotanical study of medicinal plants used to treat human diseases in Berbere district, Bale zone of Oromia regional state, south east Ethiopia. Evid Based Complement Altern Med 2018
Kefalew A, Asfaw Z, Kelbessa E (2015) Ethnobotany of medicinal plants in Ada’a District, East Shewa Zone of Oromia regional state, Ethiopia. J Ethnobiol Ethnomed 11(1):25
Khan MA, Agize M, Shonga A, Tora A (2018) The utilization and conservation of plants of medicinal value by local traditional medicinal practitioners and the associated indigenous knowledge in Dawuro Zone of Ethiopia: Northeast Africa—an ethnobotanical approach. In: Ozturk M, Hakeem KR (eds) Plant and human health, vol 1. Springer, Berlin, pp 267–321
Lulekal E (2014) Plant diversity and ethnobotanical study of medicinal plants in Ankober District, North Shewa Zone of Amhara Region. Addis Ababa University, Addis Ababa
Lulekal E, Asfaw Z, Kelbessa E, Van Damme P (2014) Ethnoveterinary plants of Ankober District, North Shewa Zone, Amhara Region, Ethiopia. J Ethnobiol Ethnomed 10(1):21
Mazid M, Khan TA, Mohammad F (2012) Medicinal plants of rural India: a review ofuse by Indian folks. Indo Glob J Pharm Sci 2(3):286–304
Megersa M, Asfaw Z, Kelbessa E, Beyene A, Woldeab B (2013) An ethnobotanical study of medicinal plants in Wayu Tuka district, east Welega zone of oromia regional state, West Ethiopia. J Ethnobiol Ethnomed 9(1):68
Mellanby K (1941) Transmission of scabies. Br Med J 2(4211):405
Mellanby K (1944) The development of symptoms, parasitic infection and immunity in human scabies. Parasitology 35(4):197–206
Mengesha GG (2016) Ethnobotanical survey of medicinal plants used in treating human and livestock health problems in Mandura Woreda of Benishangul Gumuz, Ethiopia. Adv Med Plant Res 4(1):11–26
Mesfin F, Seta T, Assefa A (2014) An ethnobotanical study of medicinal plants in Amaro Woreda, Ethiopia. Ethnobot Res Appl 12:341–354
Misha G, Yarlagadda R, Wolde-Mariam M (2014) Knowledge, attitude, practice and management of traditional medicine among people of Shopa Bultum, Southeast Ethiopia. Res J Pharmaceut Biol Chem Sci 5(5):152–170
Morsy TA, Bakr ME, Ahmed MM, Kotb M (1994) Human scabies acquired from a pet puppy. J Egypt Soc Parasitol 24(2):305–308
Ogutu AI, Lilechi DB, Mutai C, Bii C (2012) Phytochemical analysis and antimicrobial activity of Phytolacca dodecandra, Cucumis aculeatus and Erythrina excelsa. Int J Biol Chem Sci 6(2):692–704
Pankhurst R (2006) Traditional Ethiopian knowledge of medicine and surgery, an introduction of sources. Organization for Social Science Research in Eastern and Southern Africa
Powell J, Whalley W (1969) Triterpenoid saponins from Phytolacca dodecandra. Phytochemistry 8(10):2105–2107
Sara J, Haji Y, Gebretsadik A (2018) Scabies outbreak investigation and risk factors in east Badewacho district, Southern Ethiopia: unmatched case control study. In: Naldi L (ed) Dermatology research and practice, vol 2018
Spengel SM (1996) Two pentacyclic triterpenes from Phytolacca dodecandra roots. Phytochemistry 43(1):179–182
Spengel SM, Luterbacher S, Schaffner W (1995) New aspects on the chemotaxonomy of Phytolacca dodecandra with regard to the isolation of phytolaccagenin, phytolaccagenic acid and their glycosides. Planta Med 61(04):385–386
Teka A, Rondevaldova J, Asfaw Z, Demissew S, Van Damme P, Kokoska L, Vanhove W (2015) In vitro antimicrobial activity of plants used in traditional medicine in Gurage and Silti Zones, south central Ethiopia. BMC Complement Altern Med 15(1):286
Teklay A, Abera B, Giday M (2013) An ethnobotanical study of medicinal plants used in Kilte Awulaelo District, Tigray Region of Ethiopia. J Ethnobiol Ethnomed 9(1):65
Teklehaymanot T (2017) An ethnobotanical survey of medicinal and edible plants of Yalo Woreda in Afar regional state, Ethiopia. J Ethnobiol Ethnomed 13(1):40
Tewelde F, Mesfin M, Tsewene S (2017) Ethnobotanical survey of traditional medicinal practices in LaelayAdi-Yabo District, Northern Ethiopia. Int J Ophthalmol Vis Sci 2(4):80–87
Tolasa E (2007) Use and conservation of traditional medicinal plants by indigenous people in Gimbi Woreda, Western Wellega. Addis Ababa University, Ethiopia
Vos T, Flaxman AD, Naghavi M, Lozano R, Michaud C, Ezzati M et al (2012) Years lived with disability (YLDs) for 1160 sequelae of 289 diseases and injuries 1990–2010: a systematic analysis for the Global Burden of Disease Study 2010. Lancet 380(9859):2163–2196
Walton SF, Holt DC, Currie BJ, Kemp DJ (2004a) Scabies: new future for a neglected disease. Adv Parasitol 57(57):309–376
Walton SF, Dougall A, Pizzutto S, Holt D, Taplin D, Arlian L, Kemp DJ (2004b) Genetic epidemiology of Sarcoptes scabiei (Acari:Sarcoptidae) in northern Australia. Int J Parasitol 34(7):839–849
Wolde-Yohannes L, Demeke T, Mamo E, Retta N, Bulbula A (1988) The natural distribution and traditional uses of Phytolacca dodecandra in Ethiopia. IPB Res Rep 4:20–22
Wubetu M, Abula T, Dejenu G (2017) Ethnopharmacologic survey of medicinal plants used to treat human diseases by traditional medical practitioners in Dega Damot district, Amhara, Northwestern Ethiopia. BMC Res Notes 10(1):157
Yassin Z, Dadi A, Nega H (2015) Scabies outbreak investigation among “Yekolo Temaris” in Gondar Town. North Western Ethiopia. Electron J Biol 13(3):203–209
Yirga G, Zeraburk S (2011) Ethnobotanical study of traditional medicinal plants in Gindeberet District, western Ethiopia. Mediterr J Soc Sci 2(4):49–54
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Nigussie, G. A review on traditionally used medicinal plants for scabies therapy in Ethiopia. ADV TRADIT MED (ADTM) 21, 199–208 (2021). https://doi.org/10.1007/s13596-020-00453-7
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DOI: https://doi.org/10.1007/s13596-020-00453-7