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Sédation inhalée en réanimation: que reste-t-il de l’AnaConDa™ ?

Inhaled sedation in the intensive care unit: what’s the future for AnaConDa™?

  • Note Technique / Technical Note
  • Published:
Réanimation

Résumé

La sédation participe au confort du patient et occupe une place essentielle en réanimation. Plusieurs études cliniques ont rapporté l’utilisation ponctuelle des agents volatils halogénés en réanimation, mais une utilisation de longue durée n’est possible en routine que depuis la mise à disposition des cliniciens d’un filtre évaporateur dédié (AnaConDa™) [ACD]. En raison de leur faible coût et de leurs caractéristiques pharmacologiques: efficacité thérapeutique rapide, index thérapeutique élevé, utilisation possible indépendamment du patient, de son âge ou des pathologies sous-jacentes, bonne connaissance de leurs effets adverses, les agents halogénés semblent se rapprocher des agents anesthésiques idéaux en réanimation. L’objectif de cette note technique est de préciser les indications potentielles du dispositif ACD ainsi que de décrire ses grands principes d’utilisation et inconvénients potentiels.

Abstract

Sedation contributes to patient’s comfort and plays an essential role in the intensive care unit (ICU). Several clinical studies have reported the occasional use of volatile halogenated agents in the ICU; however, long-term use is possible in routine for the provision of a dedicated evaporator filter (AnaConDa™ [ACD]). Because of their low cost and pharmacological characteristics with a rapid therapeutic effect, a high therapeutic index, a possible use regardless of age and underlying medical conditions, and a good knowledge of their adverse effects, halogenated agents could be considered like possible ideal anesthetic agents in the ICU. The objective of this technical note is to clarify the potential indications of ACD device and describe its operative principles and potential drawbacks.

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Authors and Affiliations

  1. LATIM Inserm UMR 1101, Réanimation médicale et urgences adultes, CHRU de la Cavale Blanche, Brest, France

    E. L’Her

  2. université de Bretagne occidentale, F-29609, Brest cedex, France

    E. L’Her

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  1. E. L’Her
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Correspondence to E. L’Her.

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L’Her, E. Sédation inhalée en réanimation: que reste-t-il de l’AnaConDa™ ?. Réanimation 23, 93–98 (2014). https://doi.org/10.1007/s13546-013-0833-1

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  • DOI: https://doi.org/10.1007/s13546-013-0833-1

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