Abstract
To improve the utility of the inedible ovary of puffer fish, heat and alkaline conditions (pH 9.0) were applied to eliminate its toxicity. The alkaline- and heat- treated ovary extract showed no lethal potential in any group tested using a mouse bioassay and a brine shrimp lethality assay. In addition, the considerable anti-erythematic and anti-edematic effects of detoxified puffer fish ovary extract were evaluated. Based on the results, detoxified puffer fish ovary extract is a promising source of novel anti-inflammatory agents that may be useful when included in dermal care products and for the development of novel therapies for dermal diseases.
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Kim, Y.D., Kim, SK. & Choi, JS. Toxicity and anti-inflammatory activity of detoxified puffer fish ovary. Toxicol. Environ. Health Sci. 9, 116–122 (2017). https://doi.org/10.1007/s13530-017-0311-7
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DOI: https://doi.org/10.1007/s13530-017-0311-7