Skip to main content
SpringerLink
Log in

Lung Function in Adolescents Exposed to Environmental Contamination and Brickworks in Guadalajara, Mexico

  • Research Paper
  • Published:
Indian Pediatrics Aims and scope Submit manuscript

Abstract

Objective

To compare the pulmonary function in adolescents exposed to different concentrations of air pollutants in two different zones.

Methods

Two zones based on monitoring of environmental pollutant concentration as high (zone 1) and low (zone 2) were chosen. The lung functions of apparently healthy adolescents (12–15 years) residing in two zones were measured for forced vital capacity (FVC), forced expiratory volume in first second (FEV1), FEV1/FVC ratio, and forced expiratory flow (FEF)25–75.

Results

A total of 302 adolescents (142, zone 1 and 160, zone 2) resided in the study area, with higher than permissible concentrations of PM10 and ozone at both places. Abnormal lung functions were seen in a higher proportion of adolescents in zone 1 than zone 2 (23% and 14%; P=0.04). A significantly lower mean (SD) FEV1 was seen in adolescents in zone 1 than zone 2 [2.9 (0.5) vs. 3.2 (0.4) L, P = 0.04]. A higher proportion of abnormal FEV1/FVC ratio% was seen in zone 1 than 2 (12% vs. 6%, P=0.04), suggestive of an obstructive pattern on spirometry. Higher risk (β 95% CI) for abnormal lung functions was seen with the zone [2.2 (1.1–4.2)], diagnosis of asthma [5.74 (2.4–13.2)], and living within 500 meters from a brickwork [1.8 (1.0–2.5)].

Conclusion

High exposure to PM10, ozone and living near brickwork were associated with reduced lung function in adolescents.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Similar content being viewed by others

References

  1. Landrigan PJ, Fuller R, Fisher S, Suk WA, Sly P, Chiles TC, et al. Pollution and children’s health. Sci Total Environ. 2019;650:2389–94.

    Article  CAS  Google Scholar 

  2. Schultz ES, Litonjua AA, Melen E. Effects of long-term exposure to traffic-related air pollution on lung function in children. Curr Allergy Asthma Rep. 2017;17:41.

    Article  CAS  Google Scholar 

  3. Lelieveld J, Haines A, Pozzer A. Age-dependent health risk from ambient air pollution: a modelling and data analysis of childhood mortality in middle-income and low-income countries. Lancet Planet Health. 2018;2:e292–e300.

    Article  Google Scholar 

  4. Goldizen FC, Sly PD, Knibbs LD. Respiratory effects of air pollution on children. Pediatr Pulmonol. 2016;51:94–108.

    Article  Google Scholar 

  5. Chen Z, Salam MT, Eckel SP, Breton CV, Gilliland FV. Chronic effects of air pollution on respiratory health in Southern California children: Findings from the Southern California Children’s Health Study. J Thorac Dis. 2015;7:46–58.

    PubMed  PubMed Central  Google Scholar 

  6. MacIntyre EA, Gehring U, Molter A, Fuertes E, Klumper C, Kramer U, et al. Air pollution and respiratory infections during early childhood: an analysis of 10 European birth cohorts within the ESCAPE project. Environ Health Perspect. 2014;122:107–13.

    Article  CAS  Google Scholar 

  7. Rojas-Martinez R, Perez-Padilla R, Olaiz-Fernandez G, Mendoza-Alvarado L, Moreno-Macias H, et al. Lung function growth in children with long-term exposure to air pollutants in Mexico City. Am J Respir Crit Care Med. 2007;176: 377–84.

    Article  CAS  Google Scholar 

  8. SEMADET. Secretaria de Medio Ambiente y Desarrollo Territorial. Gobierno del Estado de Jalisco. 2016 Informe anual de la calidad del aire. Available at: http://siga.jalisco.gob.mx/aire/reportes/ReporteAire2015.pdf. Accessed April 28, 2020.

  9. Graham BL, Steenbruggen I, Miller MR, Barjaktarevic IZ, Cooper BG, Hall GL, et al. Standardization of spirometry 2019 update. An official American Thoracic Society and European Respiratory Society technical statement. Am J Respir Crit Care Med. 2019;200:e70–e88.

    Article  Google Scholar 

  10. Hankinson JL, Odencrantz JR, Fedan KB. Spirometric reference values from a sample of the general U.S. population. Am J Respir Crit Care Med. 1999;159:179–87.

    Article  CAS  Google Scholar 

  11. World Health Organization. WHO Air Quality Guidelines for Particulate Matter, Ozone, Nitrogen Dioxide and Sulfur Dioxide: Global update 2005: Summary of Risk Assessment. Accessed April 28, 2020. Available from: https://www.who.int/phe/health-topics/outdoorair/outdoorair_aqg/en/

  12. Linares B, Guizar JM, Amador N, García A, Miranda V, Perez JR, et al. Impact of air pollution on pulmonary function and respiratory symptoms in children. Longitudinal repeated-measures study. BMC Pulm Med. 2010; 10:62.

    Article  Google Scholar 

  13. Lu F, Xu D, Cheng Y, Dong S, Guo C, Jiang X, et al. Systematic review and meta-analysis of the adverse health effects of ambient PM2.5 and PM10 pollution in the Chinese population. Environ Res. 2015; 136:196–204.

    Article  CAS  Google Scholar 

  14. Kim KH, Kabir E, Kabir S. A review on the human health impact of airborne particulate matter. Environ Int. 2015; 74:136–143.

    Article  CAS  Google Scholar 

  15. Flores-Ramirez R, Perez-Vazquez FJ, Medellin-Garibay SE, Camacho-Aldrete A, Vallejo-Perez M, Diaz de Leon-Martinez L, et al. Exposure to mixtures of pollutants in Mexican children from marginalized urban areas. Ann Glob Health. 2018;84:250–56.

    Article  Google Scholar 

  16. Khan MW, Ali Y, De Felice F, Salman A, Petrillo A. Impact of brick kilns industry on environmental and human health in Pakistan. Sci Total Environ. 2019;678:383–389.

    Article  CAS  Google Scholar 

  17. Romero-Calderón AT, Moreno-Macías HM, Manrique-Moreno JDF, Riojas-Rodriguez H, Torres-Ramos YD, Montoya-Estrada A, et al. Oxidative stress, lung function and exposure to air pollutants in Mexican school children with and without asthma. Salud Publica Mex. 2017;59:630–8.

    Article  Google Scholar 

  18. Milanzi EB, Koppelman GH, Smit HA, Wijga AH, Oldenwening M, Vonk JM, et al. Air pollution exposure and lung function until age 16 years: the PIAMA birth cohort study. Eur Respir J 2018; 52:1800218.

    Article  CAS  Google Scholar 

  19. Liu C, Chen R, Sera F, Vicedo-Cabrera AM, Guo Y, Tong S, et al. Ambient particulate air pollution and daily mortality in 652 cities. N Eng J Med. 2019;381:705–715.

    Article  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Department of Pediatric Pulmonology, UMAE Hospital de Pediatría CMNO, IMSS, Guadalajara, Mexico

    Roberto Hernandez-Raygoza

  2. Medical Research Division, UMAE Hospital de Pediatría CMNO, IMSS, Guadalajara, Mexico

    Alberto Tlacuilo-Parra

  3. School of Medicine, University of Colima, Colima, Mexico

    Valery Melnikov

  4. Faculty of Civil Engineering, University of Colima, Colima, Mexico

    Oliver Mendoza-Cano

Authors
  1. Roberto Hernandez-Raygoza
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Alberto Tlacuilo-Parra
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. Valery Melnikov
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. Oliver Mendoza-Cano
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Alberto Tlacuilo-Parra.

Additional information

Ethics approval

Comité Local de Investigación en Salud (CLIS); No. R-2016-1302-031, dated March 06, 2016.

Contributors

RHR, ATP: conception and designed of the study; RHR, VM: collected the data; RHR, OMC: analyzed the data; RHR, ATP: wrote the manuscript. All authors read and approved the final manuscript.

Funding

None

Competing interest

None stated.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Hernandez-Raygoza, R., Tlacuilo-Parra, A., Melnikov, V. et al. Lung Function in Adolescents Exposed to Environmental Contamination and Brickworks in Guadalajara, Mexico. Indian Pediatr 57, 1139–1142 (2020). https://doi.org/10.1007/s13312-020-2069-2

Download citation

  • Received:

  • Revised:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s13312-020-2069-2

Keywords

Search

Navigation