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Effect of different bariatric surgery methods on metabolic syndrome in patients with severe obesity

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Abstract

Bariatric surgery (BS) has been as a currently developed treatment of choice for metabolic syndrome (MetS). Which, in turn, is well-known as serious public health concern. Therefore, this study assessed the outcomes of different procedures of BS and possible predictors for improving MetS. This single-center retrospective cohort analysis included bariatric candidates between 2009 and 2017. The operational approach was chosen based on the patient’s condition, as well as the patient’s metabolic profile and the surgeon’s experience. All desired information was evaluated at baseline and 6, 12, and 24 months after the operation. Of the 1111 patients included, 918 (82.6%) were female. There was no considerable trend in the improvement of MetS over the follow-up period of each surgery group. After 6 to 24 months of follow-up, waist circumference reduction was significant in all three types of surgery, and sleeve gastrectomy resulted in the best (but not significant) improvement rates after 24 months (P = 0.079). One anastomosis gastric bypass had highest decrease in percentage of excess weight loss than other procedures (P < 0.001). Each year increase in age was associated with a 4% decrease in MetS remission. In addition, the male gender, was correlated with MetS improvement positively (P = 0.049). Each one-unit increase in hemoglobin A1c (HbA1c) reduced the MetS remission rate by 40%. All three methods of BS were similarly effective in MetS. Consider the predictive value of age, gender, and HbA1c before determining the optimum procedure for each patient is recommended.

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Data availability

Data of the study will be available based on the request from corresponding author after assessment of the request by all authors.

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Acknowledgements

The authors extend their sincere thanks to all participants and National Obesity Surgery Database team, who prepared us very useful data.

Funding

This research did not receive any specific grant from funding agencies in the public, commercial, or not-for-profit sectors. The authors received no financial support for the research, authorship, and/or publication of this article.

Author information

Authors and Affiliations

  1. Minimally Invasive Surgery Research Center, Hazrat-E Rasool General Hospital, Iran University of Medical Sciences, Masouri St. Niyayesh St. Satarkhan Ave, Tehran, Iran

    Ali Kabir, Simin Izadi, Kamyar Shokraee, Hastimansooreh Ansar, Farnaz Farsi & Abdolreza Pazouki

  2. Department of Epidemiology, School of Public Health, Iran University of Medical Sciences, Tehran, Iran

    Simin Izadi

  3. Rasoul Akram Hospital, Iran University of Medical Sciences (IUMS), Tehran, Iran

    Farzaneh Mashayekhi

  4. Department of Epidemiology, School of Public Health, Radiation Biology Research Center, Iran University of Medical Sciences, Tehran, Iran

    Shahnaz Rimaz

  5. Department of Cellular and Molecular Nutrition, School of Nutritional Sciences and Dietetics, Tehran University of Medical Sciences, Tehran, Iran

    Hastimansooreh Ansar

  6. Center of Excellence of European Branch of International Federation for Surgery of Obesity, Hazrat-E Rasool Hospital, Tehran, Iran

    Abdolreza Pazouki

  7. Iran National Center of Excellence for Minimally Invasive Surgery Education, Iran University of Medical Sciences, Tehran, Iran

    Abdolreza Pazouki

Authors
  1. Ali Kabir
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  2. Simin Izadi
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  3. Farzaneh Mashayekhi
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  4. Kamyar Shokraee
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  6. Hastimansooreh Ansar
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  7. Farnaz Farsi
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  8. Abdolreza Pazouki
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Contributions

KA, PA, RS, IS, AH, SK, FF and MF were responsible for the study design process and conception as well as writing, approving the final version of the manuscript, and providing critical revisions, and agreement to be accountable for all aspects of the work. KA and IS helped in data collection. PA and KA as supervisor checked quality control of data and algorithms. KA and IS have made substantial contributions to analysis and interpretation of data for the work.

Corresponding author

Correspondence to Ali Kabir.

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Conflict of interest

The authors declare that they have no conflict of interest.

Ethical approval

This study was conducted in accordance with the Helsinki declaration and approved by the Research Ethics committee (Ethics number: IR.IUMS.REC 1396.32282). Written informed consent form was received from all patients at the time of first registry in our database for any possible anonymous usage from their data.

Informed consent

The written informed consent form was received from all patients at the time of the first registry in our database for any possible anonymous usage of their data.

Research involving human participants and/or animals

The present study complies with the guidelines for human studies.

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Kabir, A., Izadi, S., Mashayekhi, F. et al. Effect of different bariatric surgery methods on metabolic syndrome in patients with severe obesity. Updates Surg 76, 547–554 (2024). https://doi.org/10.1007/s13304-023-01699-x

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  • DOI: https://doi.org/10.1007/s13304-023-01699-x

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