Skip to main content

Advertisement

Log in

Abdominal wall reconstruction with intraperitoneal prosthesis in desmoid tumors surgery

  • Original Article
  • Published:
Updates in Surgery Aims and scope Submit manuscript

Abstract

Desmoid tumor (DT), also known as aggressive fibromatosis, is a rare soft tissue neoplasm. For those tumors localized in the anterior abdominal wall, radical resection and reconstruction with mesh are indicated. Due to the rarity of this disease, there have been no randomized trials, but in reported retrospective series, although it is considered a benign lesion, it is clear that local recurrence is not uncommon. Records from seven consecutive patients (1 man, 6 women; mean age 35 years, range 25–60 years) presenting with desmoid tumors of the anterior abdominal wall were analyzed. In all cases the surgical strategy was the same: wide surgical excision and immediate plastic reconstruction with ePTFE mesh after intraoperative confirmation by frozen section of disease-free margins >1 cm. No immediate postoperative complications were recorded, and no patients developed recurrence after a median follow-up period of 60 months. The long-term mean of global health status recorded was 100%. Radical resection aided by intraoperative margin evaluation by frozen sections, followed by immediate mesh reconstruction, is a safe procedure and can provide a definitive cure without functional limitations for patients with desmoid tumors of the anterior abdominal wall.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Similar content being viewed by others

References

  1. Li M, Cordon-Cardo C, Gerald WL, Rosai J (1996) Desmoid fibromatosis is a clonal process. Hum Pathol 27:939–943

    Article  PubMed  CAS  Google Scholar 

  2. Muller J (1838) Ueber den feineren Bau und die Formen der krankhaften Geschwulste. G. Reimer, Berlin, p 60

    Google Scholar 

  3. MacFarlane J (1832) Clinical reports on the surgical practice of the Glasgow Royal Infirmary. D.Robertson, Glasgow, pp 63–66

    Google Scholar 

  4. Enzinger FM, Weiss SW (1995) Soft tissue tumours, 3rd edn. Mosby, St Louis, pp 201–229

    Google Scholar 

  5. Lefevre JH, Parc Y, Kerne’is S et al (2008) Risk factors for development of desmoids tumours in familial adenomatous polyposis. Br J Surg 95:1136–1139

    Article  PubMed  CAS  Google Scholar 

  6. Lips DJ, Barker N, Clevers H, Hennipman A (2009) The role of APC and beta-catenin in the aetiology of aggressive fibromatosis (desmoids tumors). Eur J Surg Oncol 35:3–10

    Article  PubMed  CAS  Google Scholar 

  7. Lee JC, Thomas JM, Phillips S, Fisher C, Moskovic E (2006) Aggressive fibromatosis: MRI features with pathologic correlation. AJR Am J Roentgenol 186(1):247–254

    Article  PubMed  Google Scholar 

  8. Nichols RW (1923) Desmoid tumors: a report of thirty-one cases. Arch Surg 7:227–236

    Article  Google Scholar 

  9. Dozois EJ, Dozois RR (2004) Desmoid disease. In: Kelly KA, Sarr MG, Hinder RA (eds) Mayo clinic gastrointestinal surgery. Saunders, Philadelphia, pp 563–565

    Google Scholar 

  10. Lewis JJ, Boland PJ, Leung DHY, Woodruff JM, Brennan MF (1999) The enigma of desmoid tumours. Ann Surg 229:866–873

    Article  PubMed  CAS  Google Scholar 

  11. Sorensen A, Keller J, Nielsen O et al (2002) Treatment of aggressive fibromatosis. A retrospective study of 72 patients followed for 1–27 years. Acta Orthopaedica Scandinavica 73(2):213–219

    Article  PubMed  Google Scholar 

  12. Hartley JE, Church JM, Gupta S et al (2004) Significance of incidental desmoids identified during surgery for familial adenomatous polyposis. Dis Colon Rectum 47:334–340

    Article  PubMed  CAS  Google Scholar 

  13. Ambroze WL, Dozois R, Pemberton JH, Beart RW, Ilstrup DM (1992) Familial adenomatous polyposis: results following ileal pouch-anal anastomosis and ileorectostomy. Dis Colon Rectum 35:12–15

    Article  PubMed  Google Scholar 

  14. Overhaus M, Decker P, Fischer HP, Textor HJ, Hirner A (2003) Desmoid tumours of the abdominal wall. World J Surg Oncol 1:11–15

    Article  PubMed  Google Scholar 

  15. Lewis JJ, Boland PJ, Leung DH, Woodruff JM, Brennan MF (1999) The enigma of desmoid tumors. Ann Surg 229(6):866–872 (discussion 872–873)

    Article  PubMed  CAS  Google Scholar 

  16. Okuno S (2006) The enigma of desmoid tumors. Curr Treat Options Oncol 7(6):438–443

    Article  PubMed  Google Scholar 

  17. Anthony T, Rodriguez-Bigas MA, Weber T et al (1996) Desmoid tumors. J Am Coll Surg 182:369–377

    PubMed  CAS  Google Scholar 

  18. Spear MA, Jennings LC, Mankin HJ et al (1998) Individualizing management of aggressive fibromatoses. Int J Radiat Oncol Biol Phys 40:637–645

    Article  PubMed  CAS  Google Scholar 

  19. Humar A, Chou S, Carpenter B (1993) Fibromatosis in infancy and childhood: the spectrum. J Pediatr Surg 28:1446–1450

    Article  PubMed  CAS  Google Scholar 

  20. Bertani E, Chiappa A, Testori A, Mazzarol G, Biffi R, Martella S, Pace U, Soteldo J, Vigna PD, Lembo R, Andreoni B (2009) Desmoid tumors of the anterior abdominal wall: results from a monocentric surgical experience and review of the literature. Ann Surg Oncol 16(6):1642–1649

    Article  PubMed  Google Scholar 

  21. Church J, Berk T, Boman BM, Guillem J, Lynch C, Lynch P, Rodriguez-Bigas M, Rusin L, Weber T, Collaborative Group of the Americas on Inherited Colorectal Cancer (2005) Staging intra-abdominal desmoid tumors in familial adenomatous polyposis: a search for a uniform approach to a troubling disease. Dis Colon Rectum 48(8):1528–1534

    Article  PubMed  Google Scholar 

  22. Church JM (1998) Mucosal ischemia due to submucosal desmoid tumors in patients with familial adenomatous polyposis: the clinical sequala. Dis Colon Rectum 41:661–663

    Article  PubMed  CAS  Google Scholar 

  23. Hatzimarkou A, Filippou D, Papadopoulos V et al (2006) Desmoid tumor in Gardner’s Syndrome presented as acute abdomen. World J Surg Oncol 4:18–23

    Article  PubMed  Google Scholar 

  24. Reitamo JJ, Scheinin TM, Hayry P (1986) The desmoid syndrome: new aspects in the cause, pathogenesis and treatment of the desmoid tumour. Am J Surg 151:230–237

    Article  PubMed  CAS  Google Scholar 

  25. Middleton SB, Clark SK, Matravers P et al (2003) Stepwise progression of familial adenomatous polyposis-associated desmoid precursor lesions demonstrated by a novel CTscoring system. Dis Colon Rectum 46:481–485

    Article  PubMed  Google Scholar 

  26. Cassilas J, Sais GJ, Greve JL et al (1991) Imaging of intra- and extra abdominal desmoid tumors. Radiographics 11:959–968

    Google Scholar 

  27. Guglielmi G, Cifaratti A, Scalzo G, Magarelli N (2009) Imaging of superficial and deep fibromatosis. Radiol Med 114(8):1292–1307

    Article  PubMed  CAS  Google Scholar 

  28. Church J, Berk T, Boman BM et al (2005) Staging intra-abdominal desmoid tumors in familial adenomatous polyposis: a search for a uniform approach to a troubling disease. Dis Colon Rectum 48:1528–1534

    Article  PubMed  Google Scholar 

  29. Clark SK, Neale KF, Landgrebe JC, Phillips RKS (1999) Desmoid tumors complicating familial adenomatous polyposis. Br J Surg 86:1185–1189

    Article  PubMed  CAS  Google Scholar 

  30. Middleton SB, Phillips RK (2000) Surgery for large intra-abdominal desmoid tumors: report of four cases. Dis Colon Rectum 43:1759–1762

    Article  PubMed  CAS  Google Scholar 

  31. Brenner P, Rammelt S (2002) Abdominal wall and foot reconstruction after extensive desmoid tumor resection with free tissue transfer. Langenbecks Arch Surg 386:592–597

    Article  PubMed  CAS  Google Scholar 

  32. Sutton RJ, Thomas JM (1999) Desmoid tumours of the anterior abdominal wall. Eur J Surg Oncol 25:398–400

    Article  PubMed  CAS  Google Scholar 

  33. Ballo MT, Zagars GK, Pollack A (1999) Desmoid tumor: prognostic factors and outcome after surgery, radiation therapy, or combined surgery and radiation therapy. J Clin Oncol 17:158–167

    PubMed  CAS  Google Scholar 

  34. Croce E, Olmi S (2006) Chirurgia della parete addominale. Elsevier Masson, Italy

    Google Scholar 

  35. Rohrich RJ, Lowe JB, Hackney FL, Bowman JL, Hobar PC (2000) An algorithm for abdominal wall reconstruction. Plast Reconstr Surg 105:202–216

    Article  PubMed  CAS  Google Scholar 

  36. Bauer JJ, Salky BA, Gelernt IM, Kreel I (1987) Repair of large abdominal wall defects with expanded polytetrafluoroethylene (PTFE). Ann Surg 206:765–769

    Article  PubMed  CAS  Google Scholar 

  37. Sagar PM, Möslein G, Dozois RR (1998) Management of desmoid tumors in patients after ileal pouch-anal anastomosis for familial adenomatous polyposis. Dis Colon Rectum 41:1350–1355 (discussion 1355–1356)

    Article  PubMed  CAS  Google Scholar 

  38. Latchford AR, Sturt NJH, Neale K et al (2006) A 10 year review of surgery for desmoid disease associated with familial adenomatous polyposis. Br J Surg 93:1258–1264

    Article  PubMed  CAS  Google Scholar 

  39. Johner A, Tiwari P, Zetler P, Wiseman SM (2009) Abdominal wall desmoid tumors associated with pregnancy: current concepts. Expert Rev Anticancer Ther 9(11):1675–1682

    Article  PubMed  Google Scholar 

  40. Nuyttens J, Rust P, Thomas C et al (2000) Surgery versus radiation therapy for patients with aggressive fibromatosis or desmoid tumors. A comparative review of 22 articles. Cancer 88(7):1517–1523

    Article  PubMed  CAS  Google Scholar 

  41. Sherman NE, Romsdahl M, Evans H et al (1990) Desmoid tumors. A 20 year radiotherapy experience. Int J Radiat Oncol Biol Phys 19:37–40

    Article  PubMed  CAS  Google Scholar 

  42. Easter DW, Halasz NA (1989) Recent trends in the management of desmoid tumors—summary of 19 cases and review of the literature. Ann Surg 2102(6):765–769

    Article  Google Scholar 

  43. Ilaslan H, Schils J, Joyce M, Marks K, Sundaram M (2010) Radiofrequency ablation: another treatment option for local control of desmoid tumors. Skeletal Radiol 39(2):169–173

    Article  PubMed  Google Scholar 

  44. Heinrich MC, Mc Arthur G, Demetri GD et al (2006) Clinical and molecular studies of the effect of imatinib on advanced aggressive fibromatosis (desmoid tumor). J Clin Oncol 24:1195–1203

    Article  PubMed  CAS  Google Scholar 

  45. Janinis J, Patriki M, Vini L et al (2003) The pharmacological treatment of aggressive fibromatosis: a systematic review. Ann Oncol 14:181–190

    Article  PubMed  CAS  Google Scholar 

  46. Vasen HF, Möslein G, Alonso A, Aretz S, Bernstein I, Bertario L, Blanco I, Bülow S, Burn J, Capella G, Colas C, Engel C, Frayling I, Friedl W, Hes FJ, Hodgson S, Järvinen H, Mecklin JP, Møller P, Myrhøi T, Nagengast FM, Parc Y, Phillips R, Clark SK, de Leon MP, Renkonen-Sinisalo L, Sampson JR, Stormorken A, Tejpar S, Thomas HJ, Wijnen J (2008) Guidelines for the clinical management of familial adenomatous polyposis (FAP). Gut 57(5):704–713

    Article  PubMed  CAS  Google Scholar 

Download references

Conflict of interest

None.

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Gaetano Catania.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Catania, G., Ruggeri, L., Iuppa, G. et al. Abdominal wall reconstruction with intraperitoneal prosthesis in desmoid tumors surgery. Updates Surg 64, 43–48 (2012). https://doi.org/10.1007/s13304-011-0109-0

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s13304-011-0109-0

Keywords

Navigation