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RETRACTED ARTICLE: Improving the diagnosis, treatment, and biology patterns of feline mammary intraepithelial lesions: a potential model for human breast masses with evidence from epidemiologic and cytohistopathologic studies

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Tumor Biology

This article was retracted on 05 November 2016

Abstract

In this study, the frequency of different types of mammary masses and their relationship with cytohistopathologic changes was investigated and data on history, macroscopic description, clinical examination and treatment were collected. To determine the prevalence and types of cytohistopathologic changes, mammary glands from 12 female cats were evaluated. The mean age of cats at the time of diagnosis was 11.5 ± 1.9 years (range 4–14 years), the mean gross size of the masses was 3.1 ± 2.4 cm, 4/12 (33.3 %) masses were ≤3.0 cm in diameter, and the maximum diameter of the largest mass had a median of 5 cm, with a range of diameter of 6 × 5 × 4 cm. Moreover, the preferential localization of mammary masses was the abdominal lobes (%50) and thoracic lobes (%33.3), and inguinal lobes (%16.7 of cases). Furthermore, two cases of the inguinal masses affected the caudo-inguinal lobe, six cases caudo-abdominal lobe, and thoracic masses were found in four cases. Eventually, six cases (%50) of masses were found in the right mammary lobes and six cases (%50) in the left mammary lobes. The majority of the masses revealed elastic (%50 of cases), hard (%25 of cases), or soft (%25 of cases) consistency. In the present study, according to the criteria of the veterinary and the medical WHO classification system, of the 12 cats with the cytohistopathological features of six (50 %) cases qualified abscess, 3 (25 %) cases as cystic hyperplasia and 3 (25 %) cases were called situ carcinoma. Whereas, all hyperplastic lesions (case nos. 7–9 and ranging in size from, 1 to >4 cm3) and carcinomas in situ lesions (case nos. 10–12 and ranging in size from, 1 to >3 cm3) were found incidentally upon routine cytohistology. Other lesions were observed grossly and removed either at surgery (case nos. 1–6). Finally, the cats were treated with unilateral lumpectomy (3 cases) and also, nine (75 %) cases had subsequent drainage, 3 (25 %) of which showed cystic hyperplasia and 6 (50 %) showed abscess on subsequent histopathological evaluation. Therefore, a correct diagnosis must be established quickly, and treatment must be instituted rapidly when alteration is noted in the mammary glands.

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Acknowledgments

The authors thank Solmaz and Mahdieh Javanbakht for their help with this manuscript.

Conflicts of interest

None

Author information

Authors and Affiliations

  1. Gradute of Islamic Azad University of Shahrekord, Faculty of Veterinary Medicine, Shahrekord University, Shahrekord, Iran

    Javad Yaghoobi Yeganeh Manesh

  2. Graduate, Faculty of Veterinary Medicine, Tehran University, Tehran, Iran

    Radmehr Shafiee & Farshid Khadivar

  3. Department of Pathobiology, Susangerd Branch, Islamic Azad University, Susangerd, Iran

    Behnam Pedram

  4. Department of Internal Medicine, Faculty of Veterinary Medicine, Tehran University, Tehran, Iran

    Hamed Zamankhan Malayeri

  5. Chronic Respiratory Disease Research Center, National Research Institue of Tuberculosis and Lung Diseases, Massih Daneshvary Hospital, Shahid Beheshti University of Medicine, Tehran, Iran

    Sheida Mohajer

  6. Faculty of Medicine, Kermanshah University of Medical Sciences, Kermanshah, Iran

    Sharareh Ahmadi & Shirin Ahmadi

  7. Department of Pathology, Faculty of Veterinary Medicine, Tehran University, Tehran, Iran

    Javad Javanbakht

  8. Department of Immunology, Faculty of Medicine, Kurdistan University of Medical Sciences, Sanandaj, Iran

    Aram Mokarizadeh

Authors
  1. Javad Yaghoobi Yeganeh Manesh
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  2. Radmehr Shafiee
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  3. Behnam Pedram
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  4. Hamed Zamankhan Malayeri
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  5. Sheida Mohajer
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  7. Shirin Ahmadi
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  8. Javad Javanbakht
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  9. Aram Mokarizadeh
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  10. Farshid Khadivar
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Corresponding authors

Correspondence to Javad Javanbakht or Aram Mokarizadeh.

Additional information

An erratum to this article is available at http://dx.doi.org/10.1007/s13277-016-5472-5.

This article has been retracted at the request of the Editor-in-Chief, the International Society of Oncology and BioMarkers (ISOBM) and the Publisher per the Committee on Publication Ethics guidelines. The article shows evidence of irregularities in authorship during the submission process, there is strong reason to believe that the peer review process was compromised and the following figure has been duplicated:

Fig 7 "Photomicrography of fine needle cytology from malignant mammary tumor in a cat; variation in cell (anisocytosis) and nuclear (anisokaryosis) size are present,May-Grunwald-Giemsa stainingmethod, x 1,000" is duplicating Fig 1B "Coarse chromatin structures in all samples and lightly basophilic cytoplasm were associated with tumor cells, and these cells were round or ovoid, containing single, large, round nuclei of variable size, coarse nuclear chromatin, and single, prominent, centrally placed nucleoli also cell's nucleus, and nuclei were clear." published in: J. Javanbakht, B. Pedram, M. R. Taheriyan, F. Khadivar, S. H. Hosseini, F. S. Abdi, E. Hosseini, M. Moloudizargari, S H. Aghajanshakeri, S. Javaherypour, R. Shafiee, R. Emrani Bidi, Canine transmissible venereal tumor and seminoma: a cytohistopathology and chemotherapy study of tumors in the growth phase and during regression after chemotherapy, Tumor Biol. 2014; 35:6 5493-5500 DOI: 10.1007/s13277-014-1723-5

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Manesh, J.Y.Y., Shafiee, R., Pedram, B. et al. RETRACTED ARTICLE: Improving the diagnosis, treatment, and biology patterns of feline mammary intraepithelial lesions: a potential model for human breast masses with evidence from epidemiologic and cytohistopathologic studies. Tumor Biol. 35, 12109–12117 (2014). https://doi.org/10.1007/s13277-014-2515-7

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  • DOI: https://doi.org/10.1007/s13277-014-2515-7

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