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Development and evaluation of photon-counting Cd0.875Zn0.125Te0.98Se0.02 detector for measuring bone mineral density

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Abstract

Cadmium zinc telluride (CZT) has been actively researched and developed by researchers in various fields. In medical applications, especially photon-counting, CZT enables improved image quality, multi-material decomposition, and improved dose efficiency. Moreover, band gap engineering and selenium addition on CZT improved electrical, spectroscopic and structural properties, thereby supporting performance of CZT as a photon-counting detector. In this study, it is shown that Cd0.875Zn0.125Te0.98Se0.02 (CZTS) shows sufficient performance without loss of detection efficiency. We carried out a study involving the application of this CZTS on calculating bone mineral density (BMD) values, because this application has a novelty of new material for BMD sensor which follows the CdTe- or CdZnTe- based BMD detector. Anatomical images from different energy bins contained different information of attenuation although the images were taken in the same region at the same time. Moreover, calculated BMD values had a proper tendency depending on the amount of bone in that region. The final BMD value was 1.1972 g/cm2, which is close to the real value of 1.2 g/cm2. The introduction with a bone filter and a smaller pixel size will improve the accuracy and precision of photon-counting CZTS detectors for measuring BMD values. However, in this study the CZTS showed the feasibility that a photon-counting CZTS detector can help the measurement of BMD values and the diagnosis of osteoporosis.

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Data availability

The data that support the findings of this study are available from the corresponding author, [B. Park], upon reasonable request.

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Acknowledgements

This work was supported by the National Research Foundation of Korea (NRF) grant funded by the Korea government (MSIT) (No.2018M2A2B3A01072384, RS-2022-00165164) and by Korea Institute of Energy Technology Evaluation and Planning (KETEP) grant funded by the Korea government (MOTIE) (20214000000070, Promoting of expert for energy industry advancement in the field of radiation technology).

Funding

National Research Foundation of Korea, 2020R1A2C2007376, B. Park, National research foundation of korea, RS-2022-00165164, J. Seo, Korea Institute of Energy Technology Evaluation and Planning, 20214000000070, B. Park.

Author information

Authors and Affiliations

  1. Department of Health and Safety Convergence Science, Korea University, Seoul, 02841, Korea

    J. Byun, J. Seo, E. Kim & B. Park

  2. Interdisciplinary Program in Precision Public Health, Korea University, Seoul, 02841, Korea

    J. Byun, Y. Kim, J. Seo & B. Park

  3. Marine Radioactivity Monitoring Group, Korea Marine Environment Management Corporation, Busan, 48931, Korea

    Y. Kim

  4. Department of Health and Environmental Science, Korea University, Seoul, 02841, Korea

    K. Kim & W. Lee

  5. Health Science Research Center, Korea University, Seoul, 02841, Korea

    A. Jo

  6. Graduate School, Transdisciplinary Major in Learning Health Systems, Korea University, Seoul, 02841, Korea

    W. Lee

  7. Liquid Crystals Research Center, Konkuk University, Seoul, 05029, Korea

    B. Park

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  1. J. Byun
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Correspondence to B. Park.

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Byun, J., Kim, Y., Seo, J. et al. Development and evaluation of photon-counting Cd0.875Zn0.125Te0.98Se0.02 detector for measuring bone mineral density. Phys Eng Sci Med 46, 245–253 (2023). https://doi.org/10.1007/s13246-022-01213-4

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