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Can magnetic resonance imaging after cranioplasty using titanium mesh detect brain tumors?

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Abstract

This study determined the dependence of the concentration and position of contrast-enhanced tumors on the radio frequency (RF)-shielding effect of titanium mesh using the contrast-to-noise ratio (CNR) in magnetic resonance imaging (MRI). A phantom was constructed by filling a plastic container with manganese chloride tetrahydrate and agar. Four cellophane cylindrical containers were arranged from the end of the plastic container, and the brain tumor model was filled with gadobutrol diluted with NaCl, with molarity values of 0.2–1.0 mmol/L. The titanium mesh board was set on the left side of the phantom. Images were acquired using a 1.5-T MRI as well as two-dimensional spin-echo (2D SE) and three-dimensional fast spoiled gradient echo (3D FSPGR) sequences. CNR was calculated using the signal intensity values of the tumor model, surrounding area of the brain model, and background noise. Furthermore, the fractional change in CNR was calculated using values of CNR with and without the mesh. Moreover, a profile of CNR was created. The fractional change in CNR decreased at the brain tumor positions present near the mesh and at a contrast medium concentration of approximately ≤ 0.5 mmol/L in 2D SE and ≤ 0.25 mmol/L in 3D FSPGR. According to the CNR profiles, directly under the mesh, almost all contrast concentrations in 2D SE was unrecognizable; however, at a concentration of ≥ 0.5 mmol/L in 3D FSPGR was recognizable.

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Data availability

The datasets generated during and/or analysed during the current study are available from the corresponding author on reasonable request.

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Acknowledgements

The titanium mesh was provided by Bear Medic Corporation (Ibaraki, Japan).

Funding

The authors declare that no funds, grants, or other support were received during the preparation of this manuscript.

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Authors and Affiliations

  1. Molecular Imaging, School of Medical Sciences, Fujita Health University, 1-98, Dengakugakubo, Kutsukake-cho, Toyoake, Aichi, 470-1192, Japan

    Yasuo Takatsu

  2. Division of Health Sciences, Graduate School of Medical Sciences, Kanazawa University, 5-11-80 Kodatsuno, Kanazawa, 920-0942, Japan

    Yasuo Takatsu & Tosiaki Miyati

  3. Department of Radiology, Kurihara Central Hospital, 3-3-1 Miyano chuo, Tsukidate, Kurihara-city, Miyagi, 987-2205, Japan

    Rei Yoshida

  4. Division of Central Radiology, Nara Medical University Hospital, 840, Shijo-Cho, Kashihara, Nara, 634-8522, Japan

    Yuya Yamatani

  5. Department of Radiological Technology, Minami Matsuyama Hospital, 3-10, Asodamachi, Matsuyama, Ehime, 790-8534, Japan

    Mikihisa Kanno

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Contributions

All author contributed to the study conception and design. Material preparation and data collection were performed by YT and MK. Analysis was performed by YT, RY and YY. This study was supervised by TM. The first draft of the manuscript was written by YT, and all authors commented on previous version of the manuscript. All authors read and approved the final manuscript.

Corresponding author

Correspondence to Yasuo Takatsu.

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Competing interest

Financial interests: The authors have no relevant financial interests to disclose. Non-financial interests: Author Yasuo Takatsu has was provided with the titanium mesh by Bear Medic Corporation (Ibaraki, Japan).

Ethical approval

This is an observational study. The Fujita Health University Ethics Committee has confirmed that no ethical approval is required.

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This was a phantom study that did not involve any patient. Therefore, informed consent was not required.

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Takatsu, Y., Yoshida, R., Yamatani, Y. et al. Can magnetic resonance imaging after cranioplasty using titanium mesh detect brain tumors?. Phys Eng Sci Med 46, 109–118 (2023). https://doi.org/10.1007/s13246-022-01200-9

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  • DOI: https://doi.org/10.1007/s13246-022-01200-9

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