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Development of a method for treating lower-eyelid carcinomas using superficial high dose rate brachytherapy

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Abstract

In this study, a method was developed for delivering high dose rate (HDR) brachytherapy treatments to basal cell carcinomas (BCCs) as well as squamous cell carcinomas (SCCs) of the lower eyelid via superficial catheters. Clinically-realistic BCC/SCC treatment areas were marked in the lower-eyelid region on a head phantom and several arrangements of catheters and bolus were trialled for treating those areas. The use of one or two catheters of different types was evaluated, and sources of dosimetric uncertainty (including air gaps) were evaluated and mitigated. Test treatments were planned for delivery with an iridium-192 source, using the Oncentra Brachy treatment planning system (Elekta AB, Stockholm, Sweden). Dose distributions were evaluated using radiochromic film. The proposed method was shown to be clinically viable, for using superficial HDR brachytherapy to overcome anatomical difficulties and create non-surgical treatments for BCC and SCC of the lower eyelid.

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Funding

This study was not funded by any grant.

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Author notes

  1. C. Deans

    Present address: Icon Integrated Cancer Centre, 9 McLennan Ct, North Lakes, Qld, 4509, Australia

Authors and Affiliations

  1. Chermside Medical Complex, Ground Floor, 956 Gympie Road, Chermside, Qld, 4032, Australia

    H. Stephens, C. Deans & D. Schlect

  2. School of Physical Sciences, University of Adelaide, North Terrace, Adelaide, SA, 5005, Australia

    H. Stephens

  3. Cancer Care Services, Royal Brisbane and Women’s Hospital, Herston, Qld, 4029, Australia

    T. Kairn

  4. Science and Engineering Faculty, Queensland University of Technology, Gardens Point, Qld, 4001, Australia

    T. Kairn

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  1. H. Stephens
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Correspondence to H. Stephens.

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Stephens, H., Deans, C., Schlect, D. et al. Development of a method for treating lower-eyelid carcinomas using superficial high dose rate brachytherapy. Phys Eng Sci Med 43, 1317–1325 (2020). https://doi.org/10.1007/s13246-020-00935-7

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  • DOI: https://doi.org/10.1007/s13246-020-00935-7

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