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Development of simple high-precision two-dimensional dose-distribution measurement method for proton beam therapy using imaging plate and EBT3

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Abstract

Although there are several two-dimensional (2D) dose-distribution measurement methods using proton beam therapy, they all have drawbacks; hence, there is no standard method established worldwide. The purpose of this study was to develop a simple, high-precision 2D distribution measurement method for proton beam therapy that uses an imaging plate and EBT3. First, we expanded the maximum readable dose (saturation dose) in the imaging plate. The method involves (i) the control of the fading phenomenon by an annealing process and (ii) the control of the photostimulated luminescence (PSL) phenomenon using a longpass filter (LPF). In method (i), upon heating at 80 °C, the PSL became 0.485 times the room temperature, and in method (ii), we attenuated the PSL by a factor of 0.245 using an LPF. Thus, by combining methods (i) and (ii), we expanded the saturation dose to 2 Gy. Thus, it was possible to measure the imaging plate and EBT3 in the same dose range. We simultaneously measured the percent depth dose using imaging plate and EBT3. We defined a correction factor to match the measured values—which had a reduced sensitivity because of the linear energy transfer (LET) dependence of the imaging plate and EBT3—with reference data and developed a correction factor function. Subsequently, by defining the relative LET dependence of imaging plate and EBT3 as the relative sensitivity and converting the relationship imaging plate between the relative sensitivity and correction factor into a function, we obtained a sensitivity-correction function. By employing this function, measurements with the same accuracy as the reference data were performed using the imaging plate and EBT3.

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References

  1. Das IJ, Chen CW, Watts RJ et al (2008) Accelerator beam data commissioning equipment and procedures: report of the TG-106 of the Therapy Physics Committee of the AAPM. Med Phys 35:4186–4215

    Article  PubMed  Google Scholar 

  2. Ajomandy B, Sahoo N, Ding X et al (2008) Use of a two-dimensional ionization chamber array for proton therapy beam quality assurance. Med Phys 35:3889–3894

    Article  Google Scholar 

  3. Zhao L, Das IJ (2010) Gafchromic EBT film dosimetry in proton beams. Phys Med Biol 55:N291–N301

    Article  PubMed  Google Scholar 

  4. Martisíková M, Jäkel O (2010) Gafchromic EBT films for ion dosimetry. Radiat Meas 45:1268–1270

    Article  Google Scholar 

  5. Ajomandy B, Tailor R, Anand A et al (2010) Energy dependence and dose response of Gafchromic EBT2 film over a wide range of photon, electron, and proton beam energies. Med Phys 37:1942–1947

    Article  Google Scholar 

  6. Angellier G, Gautier M, Herault J (2011) Radiochromic EBT2 film dosimetry for low-energy protontherapy. Med Phys 38:6171–6177

    Article  CAS  PubMed  Google Scholar 

  7. Mumot M, Mytsin GV, Molokanov AG et al (2009) The comparison of doses measured by radiochromic films and semiconductor detector in a 175 MeV proton beam. Physica Med 25:105–110

    Article  Google Scholar 

  8. Park SA, Kwak JW, Yoon MG et al (2011) Dose verification of proton beam therapy using the Gafchromic EBT film. Radiat Meas 46:717–721

    Article  CAS  Google Scholar 

  9. Nohtomi A, Terunuma T, Kohno R et al (1999) Response characteristics of an imaging plate to clinical. Nucl Instrum Methods Phys Res A424:569–574

    Article  Google Scholar 

  10. Nohtomi A, Sakae T, Terunuma T et al (2003) Measurement of depth-dose distribution of protons. Nucl Instrum Methods Phys Res A511:382–387

    Article  Google Scholar 

  11. Ito M, Amemiya Y (1991) X-ray energy dependence and uniformity of an imaging plate detector. Nucl Instrum Methods Phys Res A310:369–372

    CAS  Google Scholar 

  12. Fujibuchi T, Tanabe Y, Sakae T et al (2011) Feasibility study on using imaging plates to estimate thermal neutron fluence in neutron-gamma mixed fields. Radiat Prot Dosim 147:394–400

    Article  CAS  Google Scholar 

  13. Amemiya Y (1995) Imaging plates for use with synchrotron radiation. J Synchrotron Radiat 2:12–21

    Article  Google Scholar 

  14. Ohuchi H, Yamadera A (2002) Dependence of fading patterns of photo-stimulated luminescence from imaging plates on radiation, energy, and image reader. Nucl Instrum Methods Phys Res A490:573–582

    Article  Google Scholar 

  15. Amemiya Y, Miyahara J (1988) Imaging plate illuminates many fields. Nature 336:89–90

    Article  CAS  PubMed  Google Scholar 

Download references

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Authors and Affiliations

  1. Graduate School of Comprehensive Human Sciences, University of Tsukuba, 1-1-1 Tennodai, Tsukuba, Ibaraki, 305-8575, Japan

    Yutaro Mori, Tomonori Isobe, Toshiyuki Terunuma, Eisuke Sato, Kiichi Tadano, Hideyuki Sakurai & Takeji Sakae

  2. Proton Medical Research Center, University of Tsukuba Hospital, 2-1-1 Amakubo, Tsukuba, Ibaraki, 305-8576, Japan

    Yutaro Mori, Tomonori Isobe, Yoshiki Yamaguchi, Hideyuki Takei, Satoshi Kamizawa, Toshiyuki Terunuma, Kenta Takada, Yousuke Yoshimura, Hideyuki Sakurai & Takeji Sakae

  3. Faculty of Medicine, University of Tsukuba, 1-1-1, Tennodai, Tsukuba, Ibaraki, 305-8575, Japan

    Tomonori Isobe, Hideyuki Takei, Satoshi Kamizawa, Toshiyuki Terunuma, Kenta Takada, Hideyuki Sakurai & Takeji Sakae

  4. Faculty of Health Sciences, Kyorin University, 4-7-6 Miyashita-machi, Hachioji, Tokyo, 192-8508, Japan

    Eisuke Sato & Kiichi Tadano

Authors
  1. Yutaro Mori
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  2. Tomonori Isobe
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  3. Yoshiki Yamaguchi
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  4. Hideyuki Takei
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  5. Satoshi Kamizawa
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  6. Toshiyuki Terunuma
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  7. Eisuke Sato
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  8. Kenta Takada
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  9. Kiichi Tadano
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  10. Yousuke Yoshimura
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  11. Hideyuki Sakurai
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  12. Takeji Sakae
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Correspondence to Yutaro Mori.

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Mori, Y., Isobe, T., Yamaguchi, Y. et al. Development of simple high-precision two-dimensional dose-distribution measurement method for proton beam therapy using imaging plate and EBT3. Australas Phys Eng Sci Med 39, 687–696 (2016). https://doi.org/10.1007/s13246-016-0464-8

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  • DOI: https://doi.org/10.1007/s13246-016-0464-8

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