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Review of 3D image data calibration for heterogeneity correction in proton therapy treatment planning

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Abstract

Correct modelling of the interaction parameters of patient tissues is of vital importance in proton therapy treatment planning because of the large dose gradients associated with the Bragg peak. Different 3D imaging techniques yield different information regarding these interaction parameters. Given the rapidly expanding interest in proton therapy, this review is written to make readers aware of the current challenges in accounting for tissue heterogeneities and the imaging systems that are proposed to tackle these challenges. A summary of the interaction parameters of interest in proton therapy and the current and developmental 3D imaging techniques used in proton therapy treatment planning is given. The different methods to translate the imaging data to the interaction parameters of interest are reviewed and a summary of the implementations in several commercial treatment planning systems is presented.

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Acknowledgments

The authors would like to acknowledge J. Pollard for her constructive comments in reviewing this article.

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Authors and Affiliations

  1. Department of Physics, University of Adelaide, Adelaide, SA, 5005, Australia

    Jiahua Zhu & Scott N. Penfold

  2. Department of Medical Physics, Royal Adelaide Hospital, Adelaide, SA, 5000, Australia

    Scott N. Penfold

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  1. Jiahua Zhu
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Correspondence to Jiahua Zhu.

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Zhu, J., Penfold, S.N. Review of 3D image data calibration for heterogeneity correction in proton therapy treatment planning. Australas Phys Eng Sci Med 39, 379–390 (2016). https://doi.org/10.1007/s13246-016-0447-9

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  • DOI: https://doi.org/10.1007/s13246-016-0447-9

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