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The effect of aqueous extracts of some plants on in vitro antioxidant and antidiabetic activity of probiotic yogurt

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Abstract

In this study, aqueous extracts of some medicinal and aromatic plants (garlic, Turkish Oregano, rosemary, basil, and peppermint) were used in probiotic yogurt production to increase functionality of probiotic yogurt. The in vitro antidiabetic, antioxidant activity, total phenolic compound content and phenolic compounds of yogurts were evaluated during the 28 day of storage period. Yogurt sample with Turkish Oregano had the highest α-amylase and α-glucosidase inhibitory activity. A strong correlation was found between total phenolic compound content and antioxidant activity (r = 0.84) and between total phenolic compounds content and α-amylase inhibitory activity (r = 0.82). In conclusion, it can be said that the total phenolic compound content and in vitro antioxidant and antidiabetic activities of probiotic yogurt could be increased by adding aqueous extracts of some plants.

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References

  • Amirdivani S (2015) Inclusion of Allium sativum in yogurt and its effects on inhibition of diabetes and hypertension-associated by enzymes in vitro. Appl Food Biotechnol 2(3):29–37

    CAS  Google Scholar 

  • Amirdivani S, Baba AS (2011) Changes in yogurt fermentation characteristics, and antioxidant potential and in vitro inhibition of angiotensin-1 converting enzyme upon the inclusion of peppermint, dill and basil. LWT Food Sci Technol 44(6):1458–1464

    Article  CAS  Google Scholar 

  • Angel J, Sailesh KS, Mukkadan JK (2013) A study on Antidiabetic effect of peppermint in alloxan induced diabetic model of wistar rats. J Clin Biomed Sci 3(4):177–181

    Google Scholar 

  • Apostolidis E, Kwon YI, Shetty K (2006) Potential of select yogurts for diabetes and hypertension management. J Food Biochem 30(6):699–717

    Article  CAS  Google Scholar 

  • Asgar AM (2013) Anti-diabetic potential of phenolic compounds: a review. Int J Food Prop 16(1):91–103

    Article  CAS  Google Scholar 

  • Blum U (1998) Effects of microbial utilization of phenolic acids and their phenolic acid breakdown products on allelopathic interactions. J Chem Ecol 24(4):685–708

    Article  CAS  Google Scholar 

  • Cimo A, Soltani M, Lui HS (2013) Fortification of probiotic yogurt with ginseng (Panax quinquefolius) extract. J Food Nutr Disord 2:2

    Google Scholar 

  • Citta A, Folda A, Scalcon V, Scutari G, Bindoli A, Bellamio M, Feller E, Rigobello MP (2017) Oxidative changes in lipids, proteins, and antioxidants in yogurt during the shelf life. Food Sci Nutr 5(6):1079–1087

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Damin MR, Alcântara MR, Nunes AP, Oliveira MN (2009) Effects of milk supplementation with skim milk powder, whey protein concentrate and sodium caseinate on acidification kinetics, rheological properties and structure of nonfat stirred yogurt. LWT Food Sci Technol 42(10):1744–1750

    Article  CAS  Google Scholar 

  • El-Sayed SM, Youssef AM (2019) Potential application of herbs and spices and their effects in functional dairy products. Heliyon 5(6):e01989

    Article  PubMed  PubMed Central  Google Scholar 

  • Guarner F, Schaafsma G (1998) Probiotics. Int J Food Microbiol 39(3):237–238

    Article  CAS  PubMed  Google Scholar 

  • Gurkan H, Hayaloglu AA (2017) Volatiles and sensory characteristics of yogurt manufactured by incorporating basil (Ocimum basilicum L.). Int J Food Prop 20(1):779–789

    Article  Google Scholar 

  • Hanna ET, Aniess WIM, Khalil AFS, Abdalla EA, Hassanin E, Nagib E (2014) The effect of ginger and thyme on some biochemical parameters in diabetic rats. IOSR J Pharm Biol Sci 9(3):54–61

    Google Scholar 

  • Illupapalayam VV, Smith SC, Gamlath S (2014) Consumer acceptability and antioxidant potential of probiotic-yogurt with spices. LWT Food Sci Technol 55(1):255–262

    Article  CAS  Google Scholar 

  • Karadag, (2019) Türkiye’deki bazi tibbi ve aromatik bitkilerin antioksidan potansiyelleri ve fenolik kompozisyonlari. Avrupa Bilim Ve Teknoloji Dergisi 16:631–637

    Google Scholar 

  • Kaushik G, Satya S, Khandelwal RK, Naik SN (2010) Commonly consumed Indian plant food materials in the management of diabetes mellitus. Diabetes Metab Syndr 4(1):21–40

    Article  Google Scholar 

  • Lacroix IME, Li-Chan ECY (2013) Inhibition of dipeptidyl peptidase (DPP)-IV and α-glucosidase activities by pepsin-treated whey proteins. J Agric Food Chem 61(31):7500–7506

    Article  CAS  PubMed  Google Scholar 

  • Lai PK, Roy J (2004) Antimicrobial and chemopreventive properties of herbs and spices. Curr Med Chem 11:1451

    Article  CAS  PubMed  Google Scholar 

  • Lee YA, Eun JC, Yokozawa T (2008) Effects of proanthocyanidin preparations on hyperlipidemia and other biomarkers in mouse model of type 2 diabetes. J Agric Food Chem 56(17):7781–7789

    Article  CAS  PubMed  Google Scholar 

  • Liu F, Chen Z, Shao J, Wang C, Zhan C (2017) Effect of fermentation on the peptide content, phenolics and antioxidant activity of defatted wheat germ. Food Biosci 20:141–148

    Article  CAS  Google Scholar 

  • Liu YJ, Zhan J, Liu XL, Wang Y, Ji J, He QQ (2014) Dietary flavonoids intake and risk of type 2 diabetes: a meta-analysis of prospective cohort studies. Clin Nutr 33(1):59–63

    Article  CAS  PubMed  Google Scholar 

  • McCue PP, Shetty K (2004) Inhibitory effects of rosmarinic acid extracts on porcine pancreatic amylase in vitro. Asia Pac J Clin Nutr 13(1):101–106

    CAS  PubMed  Google Scholar 

  • Muniandy P, Shori AB, Baba AS (2016) Influence of green, white and black tea addition on the antioxidant activity of probiotic yogurt during refrigerated storage. Food Packag Shelf Life 8:1–8

    Article  Google Scholar 

  • Nasser Singab A, Youssef FS (2014) Medicinal plants with potential antidiabetic activity and their assessment. Med Aromat Plants 03(01):1–12

    Article  Google Scholar 

  • Ni H, Hayes HE, Stead D, Raikos V (2018) Incorporating salal berry (Gaultheria shallon) and blackcurrant (Ribes nigrum) pomace in yogurt for the development of a beverage with antidiabetic properties. Heliyon 4(10):e00875

    Article  PubMed  PubMed Central  Google Scholar 

  • Oboh G, Ademiluyi AO, Akindahunsi AA (2009) Changes in polyphenols distribution and antioxidant activity during fermentation of some underutilized legumes. Food Sci Technol Int 15(1):41–46

    Article  CAS  Google Scholar 

  • Oboh G, Isaac AT, Akinyemi AJ, Ajani RA (2014) Inhibition of key enzymes linked to type 2 diabetes and sodium nitroprusside induced lipid peroxidation in rats’ pancreas by phenolic extracts of avocado pear leaves and fruit. Int J Biomed Sci 10(3):210–218

    Google Scholar 

  • Satir G, Guzel-Seydim ZB (2015) Influence of Kefir fermentation on the bioactive substances of different breed goat milks. LWT- Food Sci Technol 63(2):852–858

    Article  CAS  Google Scholar 

  • Shori AB, Baba AS (2011) Cinnamomum verum improved the functional properties of bioyogurts made from camel and cow milks. J Saudi Soc Agric Sci 10(2):101–107

    CAS  Google Scholar 

  • Shori AB, Baba AS (2013) Antioxidant activity and inhibition of key enzymes linked to type-2 diabetes and hypertension by Azadirachta indica-yogurt. J Saudi Chem Soc 17(3):295–301

    Article  CAS  Google Scholar 

  • Shori AB, Baba AS (2014) Comparative antioxidant activity, proteolysis and in vitro α-amylase and α-glucosidase inhibition of Allium sativum-yogurts made from cow and camel milk. J Saudi Chem Soc 18(5):456–463

    Article  Google Scholar 

  • Sucharitha E, Estari M (2013) Evaluation of antidiabetic activity of medicinal plant extracts used by tribal communities in rural areas of Warangal district, Andhra Pradesh, India. Biol Med 5(1):20–25

    Google Scholar 

  • Şanlidere Aloĝlu H, Öner Z (2011) Determination of antioxidant activity of bioactive peptide fractions obtained from yogurt. J Dairy Sci 94(11):5305–5314

    Article  PubMed  Google Scholar 

  • Vallverdú-Queralt A, Regueiro J, Martínez-Huélamo M, Rinaldi Alvarenga JF, Leal LN, Lamuela-Raventos RM (2014) A comprehensive study on the phenolic profile of widely used culinary herbs and spices: rosemary, thyme, oregano, cinnamon, cumin and bay. Food Chem 154:299–307

    Article  PubMed  Google Scholar 

  • Value SJRI, Sathiavelu A, Sangeetha S, Archit R, Mythili S (2013) In Vitro anti-diabetic activity of aqueous extract of the medicinal plants Nigella sativa, Eugenia Jambolana. Androgr Paniculata Full Length Res Man 5(2):323–328

    Google Scholar 

  • Vankudre M, Balpande A, Athale M (2015) Comparative analysis of α-amylase inhibition and antioxidant activity of whey from cow and buffalo milk fermented with Lactobacillus species. Biomed Commun 8(1):25–28

    Google Scholar 

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Funding

This research was funded from Ege University Scientific Research Projects Coordination with 2015-ZRF-17 Project Number.

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The design of study was done by Ozer Kinik. The analysis and interpretation of data were performed by Ecem Akan, Oktay Yerlikaya, and Ozge Yildiz Bayram, The manuscript was drafted by Ecem Akan. All authors read and approved the final manuscript.

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Correspondence to Ecem Akan.

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Akan, E., Yerlikaya, O., Bayram, O.Y. et al. The effect of aqueous extracts of some plants on in vitro antioxidant and antidiabetic activity of probiotic yogurt. J Food Sci Technol 59, 3359–3366 (2022). https://doi.org/10.1007/s13197-021-05319-7

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  • DOI: https://doi.org/10.1007/s13197-021-05319-7

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