Abstract
In current research, simple centroid mixture design was applied to evaluate the interaction effects between three selected food grade stabilizers, namely, Tween 80, gelatine and pectin as stabilizing system in the formation of carotenoid nanoparticles through solvent displacement process. Both, particle size and β-carotene loss of produced nanodispersions, as selected response factors, special cubic regression models with acceptable determination coefficient (>90%) was obtained. The multiple response optimization analysis showed that the overall optimum concentration for stabilizers will be 35% w/w Tween 80, 46% w/w gelatine and 19% w/w pectin, which led to the production of β-carotene nanoparticles of spherical shape with minimum particle size of 155.8 nm and carotenoids loss of 25.3% w/w.
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References
Anarjan N, Tan CP (2013a) Developing a three component stabilizer system for producing astaxanthin nanodispersions. Food Hydrocoll 30:437–447
Anarjan N, Tan CP (2013b) Effects of selected polysorbate and sucrose ester emulsifiers on the physicochemical properties of astaxanthin nanodispersions. Molecules 18:768–777
Anarjan N, Mirhosseini H, Baharin BS, Tan CP (2010) Effect of processing conditions on physicochemical properties of astaxanthin nanodispersions. Food Chem 123:477–483
Anarjan N, Mirhosseini H, Baharin BS, Tan CP (2011a) Effect of processing conditions on physicochemical properties of sodium caseinate-stabilized astaxanthin nanodispersions. LWT-Food Sci Technol 44:1658–1665
Anarjan N et al (2011b) Effect of organic-phase solvents on physicochemical properties and cellular uptake of astaxanthin nanodispersions. J Agric Food Chem 59:8733–8741
Anarjan N, Nehdi IA, Tan CP (2013) Influence of astaxanthin, emulsifier and organic phase concentration on physicochemical properties of astaxanthin nanodispersions. Chem Cent J 7:1–11
Anarjan N, Jaberi N, Yeganeh-Zare S, Banafshehchin E, Rahimirad A, Jafarizadeh-Malmiri H (2014a) Optimization of mixing parameters for α-tocopherol nanodispersions prepared using solvent displacement method. J Am Oil Chem Soc 91:1397–1405
Anarjan N, Nehdi IA, Sbihi HM, Al-Resayes SI, Jafarizadeh-Malmiri H, Tan CP (2014b) Preparation of astaxanthin nanodispersions using gelatin-based stabilizer systems. Molecules 19:14257–14265
Anarjan N, Jafarizadeh-Malmiri H, Nehdi IA, Sbihi HM, Al-Resayes SI, Tan CP (2015) Effects of homogenization process parameters on physicochemical properties of astaxanthin nanodispersions prepared using a solvent-diffusion technique. Int J Nanomed 10:1109–1118
Fathi M, Martín Á, McClements DJ (2014) Nanoencapsulation of food ingredients using carbohydrate based delivery systems. Trend Food Sci Technol 39:18–39
Guo H, Huang Y, Qian JQ, Gong QY, Tang Y (2014) Optimization of technological parameters for preparation of lycopene microcapsules. J Food Sci Technol 51:1318–1325
Jo YJ, Kwon YJ (2014) Characterization of β-carotene nanoemulsions prepared by microfluidization technique. Food Sci Biotechnol 23:107–113
Joye IJ, McClements DJ (2013) Production of nanoparticles by anti-solvent precipitation for use in food systems. Trend Food Sci Technol 34:109–123
Montgomery DC (2001) Design and analysis of experiments. Wiley, New York
Ribeiro HS, Chu BS, Ichikawa S, Nakajima M (2008) Preparation of nanodispersions containing β-carotene by solvent displacement method. Food Hydrocoll 22:12–17
Ribeiro HS, Schuchmann HP, Engel R, Walz E, Briviba K (2010) Encapsulation of Carotenoids. In: Zuidam NJ, Nedovic V (eds) Encapsulation technologies for active food ingredients and food processing. Springer, New York, pp 211–252
Sen Gupta S, Ghosh M (2015) Formulation development and process parameter optimization of lipid nanoemulsions using an alginate-protein stabilizer. J Food Sci Technol 52:2544–2557
Tan CP, Nakajima M (2005) β-Carotene nanodispersions: preparation, characterization and stability evaluation. Food Chem 92:661–671
Yerramilli M, Ghosh S (2017) Long-term stability of sodium caseinate-stabilized nanoemulsions. J Food Sci Technol. doi:10.1007/s13197-016-2438-y
Yin LJ, Chu BS, Kobayashi I, Nakajima M (2009) Performance of selected emulsifiers and their combinations in the preparation of β-carotene nanodispersions. Food Hydrocoll 23:1617–1622
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Anarjan, N., Fahimdanesh, M. & Jafarizadeh-Malmiri, H. β-Carotene nanodispersions synthesis by three-component stabilizer system using mixture design. J Food Sci Technol 54, 3731–3736 (2017). https://doi.org/10.1007/s13197-017-2764-8
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DOI: https://doi.org/10.1007/s13197-017-2764-8