Abstract
A prospective observational study was done at the Regional Cancer Centre, Thiruvananthapuram, a tertiary referral center for cancer care in India with an aim to assess the surgical outcomes of CO2 laser resection of oral lesions in terms of operative time, blood loss, hospital stay, postoperative pain, time to re-epithelization, pathological margins achieved and the postoperative scar. The excision was performed in 30 patients with a diagnosis of either potentially malignant lesions (leucoplakia, erythroplakia) or early cancers, i.e., carcinoma in situ or T1/T2 squamous cell carcinoma of the anterior oral cavity (tongue, buccal mucosa), adhering to standard oncological principles, and the resultant defect was left for secondary healing.
Similar content being viewed by others
References
Patel CK (1964) Continuous-wave laser action on vibrational-rotational transitions of C O 2. Phys Rev 136(5A):A1187–A1193
Strauss RA (2000) Lasers in oral and maxillofacial surgery. Dent Clin N Am 44(4):851–873
Bornstein MM, Suter VG, Stauffer E, Buser D (2003) The CO2 laser in stomatology. Part 2. Schweizer Monatsschrift fur Zahnmedizin= Revue mensuelle suisse d’odonto-stomatologie= Rivista mensile svizzera di odontologia e stomatologia 113(7):766–785
Burkey MD, Garrett G (1996) Use of the laser in the oral cavity. Otolaryngol Clin N Am 29(6):949–961
Bornstein MM, Winzap-Kälin C, Cochran DL, Buser D (2005) The CO 2 laser for excisional biopsies of oral lesions: a case series study. Int J Period Restor Dentistry 25(3):221–229
Tuncer I, Özçakır-Tomruk C, Şencift K, Çöloğlu S (2010) Comparison of conventional surgery and CO2 laser on intraoral soft tissue pathologies and evaluation of the collateral thermal damage. Photomed Laser Surg 28(1):75–79
Reibel J (2003) Prognosis of oral pre-malignant lesions: significance of clinical, histopathological, and molecular biological characteristics. Crit Rev Oral Biol Med 14(1):47–62
Van der Hem PS, Nauta JM, Van der Wal JE, Roodenburg JL (2005) The results of CO 2 laser surgery in patients with oral leukoplakia: a 25 year follow up. Oral Oncol 41(1):31–37
Ishii J, Fujita K, Munemoto S, Komori T (2004) Management of oral leukoplakia by laser surgery: relation between recurrence and malignant transformation and clinicopathological features. J Clin Laser Med Surg 22(1):27–33
Tambuwala A, Sangle A, Khan A, Sayed A (2014) Excision of oral leukoplakia by CO2 lasers versus traditional scalpel: a comparative study. J Maxillofac Oral Surg 13(3):320–327
Pinheiro AL, Frame JW (1996) Surgical management of premalignant lesions of the oral cavity with the CO2 laser. Braz Dent J 7(2):103–108
Magalhaes-Junior EB, Aciole GT, Santos NR, Santos JN, Pinheiro AL (2011) Removal of oral lichen planus by CO2 laser. Braz Dent J 22(6):522–526
Hendrick DA, Meyers A (1995) Wound healing after laser surgery. Otolaryngol Clin N Am 28(5):969–986
Author information
Authors and Affiliations
Corresponding author
Ethics declarations
With informed consent from all the patients, demographics and operative details were captured in a predesigned proforma.
Rights and permissions
About this article
Cite this article
Thomas, S., Boparai, V.S., Tiwari, V.K. et al. Prospective Evaluation of Surgical Outcome After Transoral CO2 Laser Resection of Potentially Malignant and Early Oral Malignancy. Indian J Surg Oncol 9, 407–410 (2018). https://doi.org/10.1007/s13193-018-0758-2
Received:
Accepted:
Published:
Issue Date:
DOI: https://doi.org/10.1007/s13193-018-0758-2