Abstract
Mucosal melanoma of the head and neck is a rare and aggressive malignancy with poor prognosis even after extensive resection. A 76-year-old male with melanoma of the hard palate underwent CO2 laser resection as a conservative treatment to preserve his quality of life. Six months after lumpectomy the patient was asymptomatic and had no tumor activity. Recurrence is the rule. Local or regional relapse occurs at any time and patients eventually die from distant metastasis.
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References
Ascierto PA, Accorona R, Botti G, Farina D, Fossati P, Gatta G et al (2017) Mucosal melanoma of the head and neck. Crit Rev Oncol Hematol [Internet]. ;112:136–52. Available from: https://doi.org/10.1016/j.critrevonc.2017.01.019
Luna-Ortiz K, Villavicencio-Valencia V, Martinez Said H (2018) Comparative study of head and neck mucosal melanoma in 66 patients vs 226 patients with cutaneous melanoma: A survival analysis. Clin Otolaryngol [Internet]. ;43(2):691–6. Available from: https://doi.org/10.1111/coa.13000
Lyu J, Wu Y, Li C, Wang R, Song H, Ren G et al (2016) Mutation scanning of BRAF, NRAS, KIT, and GNAQ/GNA11 in oral mucosal melanoma: a study of 57 cases. J Oral Pathol Med [Internet]. ;45(4):295–301. Available from: https://doi.org/10.1111/jop.12358
Carvajal RD, Antonescu CR, Wolchok JD, Chapman PB, Roman R-A, Teitcher J et al (2011) KIT as a therapeutic target in metastatic melanoma. JAMA [Internet]. ;305(22):2327–34. Available from: https://doi.org/10.1001/jama.2011.746
Fusi A, Festino L, Botti G, Masucci G, Melero I, Lorigan P et al (2015) PD-L1 expression as a potential predictive biomarker. Lancet Oncol [Internet]. ;16(13):1285–7. Available from: https://doi.org/10.1016/S1470-2045(15)00307-1
Luna-Ortiz K, Campos-Ramos E, Pasche P, Mosqueda-Taylor A (2011) Oral mucosal melanoma: conservative treatment including laser surgery. Med Oral Patol Oral Cir Bucal [Internet]. ;16(3):e381-5. Available from: https://doi.org/10.4317/medoral.16.e381
Nakashima JP, Viégas CM, Fassizoli AL, Rodrigues M, Chamon LAG, Silva JHC et al (2008) Postoperative adjuvant radiation therapy in the treatment of primary head and neck mucosal melanomas. ORL J Otorhinolaryngol Relat Spec [Internet]. ;70(6):344–51. Available from: https://doi.org/10.1159/000163029
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Bautista-Pérez, I.J., Luna-Peteuil, Z., García-Ortega, D.Y. et al. Conservative Treatment with CO2 Laser for oral Mucosal Melanoma: A case Report. Indian J Otolaryngol Head Neck Surg 75, 1114–1116 (2023). https://doi.org/10.1007/s12070-022-03361-1
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DOI: https://doi.org/10.1007/s12070-022-03361-1