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Clinico-Psychosocial Factors Predicting Hepatocellular Carcinoma Related Knowledge Among Patients with Chronic Liver Disease

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Abstract

Regular clinical surveillance for hepatocellular carcinoma (HCC) among high-risk patients could lead to early detection and cure. Patient’s knowledge and attitude are important to the uptake rate of this surveillance. This study is aimed at assessing the level of HCC-related knowledge among patients with chronic liver disease (CLD) who are at risk of HCC and determine predictors for poor knowledge. A cross-sectional study was conducted among inpatients with CLD at the Third People’s Hospital of Kunming in China. Questionnaires were used to measure patient’s sociodemographic characteristics, HCC-related knowledge, and patient-doctor-related psychometric factors. Factor analysis was performed to explore the underlying domains captured by the knowledge questionnaire. Univariate and multivariate analyses were performed to identify independent predictors for each domain. Three common factors were derived from the exploratory factor analysis, namely, “Surveillance,” “Lifestyle,” and “Prognosis.” Patients with low educational background and a short period of having CLD were at a significantly low level of HCC-related knowledge of all three domains. On the other hand, surveillance and lifestyle but not prognosis, were associated with patient’s communication confidence with doctors. Over two-thirds of high-risk patients had low knowledge of HCC. Medical providers should pay more attention to low educational groups and newly diagnosed CLD patients.

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Acknowledgements

We thank Mr. Edward B. McNeil and Dr. Teerha Piratvisuth for proof reading the manuscript.

Funding

Dr. Zhao received a grant from Hubei University of Medicine (Grant No. 2018QDJZR14).

Author information

Authors and Affiliations

  1. The Third People’s Hospital of Kunming City, Kunming, Yunnan, China

    Jingyi Dai, Yingrong Du, Lin Zhuang & Yanli Ma

  2. Epidemiology Unit, Faculty of Medicine, Prince of Songkla University, Hat Yai, Songkhla, 90110, Thailand

    Jingyi Dai & Virasakdi Chongsuvivatwong

  3. School of Public Health and Administration, Hubei University of Medicine, Shiyan, Hubei, China

    Jun Zhao

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  1. Jingyi Dai
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  2. Jun Zhao
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Correspondence to Virasakdi Chongsuvivatwong.

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The study protocol was approved by the Ethical Committee of Faculty of Medicine, Prince of Songkla University (REC 61-048-18-1). Informed consent was signed by each patient before the interview.

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Dai, J., Zhao, J., Du, Y. et al. Clinico-Psychosocial Factors Predicting Hepatocellular Carcinoma Related Knowledge Among Patients with Chronic Liver Disease. J Canc Educ 35, 937–945 (2020). https://doi.org/10.1007/s13187-019-01545-y

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