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Outcomes of a Cancer Clinical Trial Matching Service

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Abstract

The American Cancer Society (ACS) and Coalition of Cancer Cooperative Groups (CCCG) provide a clinical trial (CT) information/matching/eligibility service (Clinical Trials Matching Service [CTMS]). Patients' demographic and clinical data, enrollment status, and self-reported barriers to CT participation were analyzed to assess enrollment rates and determinants of enrollment. During 3 years beginning October 1, 2007, the CTMS served 6,903 patients via the ACS call center. Among the 1,987 patients with follow-up information on enrollment, 219 (11.0%) enrolled in a CT; 48 of these 219 enrollees chose a CT they found via the CTMS. Patients were less likely to enroll if they had poor ECOG performance status (P = 0.032); were African American (P = 0.0003), were uninsured or had Medicaid coverage (P = 0.024), or had lower stage disease (P = 0.018). Enrollment varied by trial type/cancer site/system (P = .026). Several barriers significantly predicted nonenrollment. Broader availability of a CTMS might help improve patient participation in cancer clinical trials.

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Authors and Affiliations

  1. Department of Health Promotion, American Cancer Society, 250 Williams Street, Atlanta, GA, 30303, USA

    Ted Gansler, Katie Dahlquist & Katherine Sharpe

  2. Research Department, Statistics & Evaluation Center, American Cancer Society, 250 Williams Street, Atlanta, GA, 30303, USA

    Man Jin, Joseph Bauer & James Kepner

  3. Coalition of Cancer Cooperative Groups, 1818 Market Street Suite 1100, Philadelphia, PA, USA

    Larissa Tis, Robert Comis & Kimberly Naples

Authors
  1. Ted Gansler
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  2. Man Jin
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  3. Joseph Bauer
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  4. Katie Dahlquist
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  5. Larissa Tis
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  6. Katherine Sharpe
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  7. Robert Comis
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  8. Kimberly Naples
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  9. James Kepner
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Correspondence to Ted Gansler.

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Gansler, T., Jin, M., Bauer, J. et al. Outcomes of a Cancer Clinical Trial Matching Service. J Canc Educ 27, 11–20 (2012). https://doi.org/10.1007/s13187-011-0296-x

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  • DOI: https://doi.org/10.1007/s13187-011-0296-x

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