Abstract
Phosphomannomutase (PMM; EC 5.4.2.8) is an enzyme that catalyzes the interconversion reaction between mannose-6-phosphate and mannose-1-phosphate. However, its systematic molecular and functional investigations in algae have not hitherto been reported. In this work, with the accomplishment of the 1 000 Plant Project (OneKP) in which more than 218 species of Chromista, including 19 marine phaeophytes, 22 marine rhodophytes, 171 chlorophytes, 5 cryptophytes, 4 haptophytes, and 5 glaucophytes were sequenced, we used a gene analysis method to analyze the PMM gene sequences in algae and confirm the existence of the PMM gene in the transcriptomic sequencing data of Rhodophyta and Ochrophyta. Our results showed that only one type of PMM with four conserved motifs exists in Chromista which is similar to human PMM. Moreover, the phylogenetic tree revealed that algae PMM possibly originated from archaea.
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Foundation item: The National High Technology Research and Development Program of China under contract No.2012AA10A406; the National Natural Science Foundation of China under contract Nos 41206116, 31140070 and 31271397; Technology Project of Ocean and Fisheries of Guangdong Province under contract No. A201201E03; the Fundamental Research Funds for the Central Universities under contract No. 201262003; China Postdoctoral Science Foundation under contract No. 2011M501167; the algal transcriptome sequencing was supported by 1KP Project (www.onekp.com).
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Feng, Y., Chi, S., Liu, C. et al. The discovery of archaea origin phosphomannomutase in algae based on the algal transcriptome. Acta Oceanol. Sin. 33, 108–113 (2014). https://doi.org/10.1007/s13131-014-0447-0
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DOI: https://doi.org/10.1007/s13131-014-0447-0