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Breast cancer in previously diagnosed diffuse scleroderma: Is there a temporal relationship?

  • Report of a Case
  • Published:
Hellenic Journal of Surgery

Abstract

The coexistence of breast cancer and scleroderma is a rare entity. A close temporal relationship between both diseases onset implies a possible etiopathogenetic correlation. We present the case of a 60-yearold woman with breast cancer that occurred three months after diagnosis of scleroderma. A review of the literature is also reported.

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References

  1. Abu-Shakra M, Guillemin F, Lee P. Cancer in systemic sclerosis. Arthritis Rheum 1993;36:460–464.

    Article  PubMed  CAS  Google Scholar 

  2. Launay D, Le Berre R, Hatron PY, Peyrat JP, Hachulla E, Devulder B, Hebbar M. Association between systemic sclerosis and breast cancer: eight new cases and review of the literature. Clin Rheumatol 2004;23:516–522.

    Article  PubMed  Google Scholar 

  3. Rosenthal AK, McLaughlin JK, Gridley G, Nyren O. Incidence of cancer among patients with systemic sclerosis. Cancer 1995;76:910–914.

    Article  PubMed  CAS  Google Scholar 

  4. Hill CL, Nguyen AM, Roder D, Roberts-Thomson P. Risk of cancer in patients with scleroderma: a population based cohort study. Ann Rheum Dis 2003;62:728–731.

    Article  PubMed  CAS  Google Scholar 

  5. Chatterjee S, Dombi GW, Severson RK, Mayes MD. Risk of malignancy in scleroderma: a population-based cohort study. Arthritis Rheum 2005;52:2415–2424.

    Article  PubMed  Google Scholar 

  6. Derk CT. Associations of breast cancer development in patients with systemic sclerosis: an exploratory study. Clin Rheumatol 2007;26:1615–1619.

    Article  PubMed  Google Scholar 

  7. Lu TY, Hill CL, Pontifex EK, Roberts-Thomson PJ. Breast cancer and systemic sclerosis: a clinical description of 21 patients in a population-based cohort study. Rheumatol Int 2008;28:895–899.

    Article  PubMed  Google Scholar 

  8. Pineda V, Salvador R, Soriano J. Bilateral breast cancer associated with diffuse scleroderma. Breast 2003;12:217–219.

    Article  PubMed  CAS  Google Scholar 

  9. Scope A, Sadetzki S, Sidi Y, et al. Breast cancer and scleroderma. SkinMed 2006;5:18–24.

    Article  PubMed  Google Scholar 

  10. Roumm AD, Medsger TA Jr. Cancer and systemic sclerosis: an epidemiologic study. Arthritis Rheum 1985;28:1336–1340.

    Article  PubMed  CAS  Google Scholar 

  11. Lee P, Alderdice C, Wilkinson S, Keystone EC, Urowitz MB, Gladman DD. Malignancy in progressive systemic sclerosis, association with breast cancer. J Reumatol 1983;10:665–666.

    CAS  Google Scholar 

  12. Forbes AM, Woodrow JC, Verbov JL, Graham RM. Carcinoma of breast and scleroderma: four further cases and a literature review. Br J Reumatol 1989;28:65–69.

    Article  CAS  Google Scholar 

  13. Wooten M. Systemic sclerosis and malignancy: a review of the literature. South Med J 2008;101:59–62.

    PubMed  Google Scholar 

  14. Wenzel J. Scleroderma and malignancy: mechanisms of interrelationship. Eur J Dermatol 2002;12:296–300.

    PubMed  CAS  Google Scholar 

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Correspondence to H. Harissis.

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Harissis, H., Papanikolaou, G.E., Batsis, C. et al. Breast cancer in previously diagnosed diffuse scleroderma: Is there a temporal relationship?. Hellenic J Surg 83, 29–32 (2011). https://doi.org/10.1007/s13126-011-0005-6

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  • DOI: https://doi.org/10.1007/s13126-011-0005-6

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