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Stent implantation for May–Thurner syndrome with acute deep venous thrombosis: acute and long-term results from the ATOMIC (AcTive stenting for May–Thurner Iliac Compression syndrome) registry

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Abstract

The outcomes of stent implantation in managing May–Thurner syndrome (MTS) are not well understood. To clarify the acute and long-term outcomes of stent implantation in patients with MTS having acute deep venous thrombosis (DVT), we retrospectively investigated consecutive 59 patients from 10 hospitals in Japan who were treated with stents for left iliac vein stenosis with acute DVT. Stents were considered successful if the stent was patent at discharge, which in turn was defined as patient success. The primary endpoint for the study was stent patency, and the secondary endpoint was recurrence of DVT and development of post-thrombotic syndrome (PTS) during follow-up. The patient success was achieved in 56 patients (95%). Clinical follow-up was conducted for 50 patients (89%) for a median duration of 40 months (range 8–165 months). Among them, 44 patients (79%) were followed up using imaging modalities. During this period, stent occlusion was revealed in four patients (9%), and one patient was successfully treated using balloon angioplasty. Primary and secondary patency rates were 84% at 19 months and 93% at 20 months, respectively. Recurrence of DVT was documented in 3 (8%) patients. PTS was evaluated from 36 patients. Three patients (8%) had PTS; however, none of the patients had severe PTS. This multicenter retrospective study of the use of stents for treating patients with MTS having acute DVT demonstrated good acute and long-term outcomes and long-term stent patency.

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Authors and Affiliations

  1. Kyoto Katsura Hospital, 17 Yamada hirao-cho, Nishikyo-ku, Kyoto, 615-8256, Japan

    Atsushi Funatsu & Shigeru Nakamura

  2. Ota Memorial Hospital, Gunma, Japan

    Hitoshi Anzai

  3. Metropolitan Hiroo Hospital, Tokyo, Japan

    Kota Komiyama

  4. Hiroshima City Hiroshima Citizen’s Hospital, Hiroshima, Japan

    Kuniomi Oi

  5. Showa University Northern Yokohama Hospital, Kanagawa, Japan

    Hiroshi Araki

  6. St. Marianna University School of Medicine, Kanagawa, Japan

    Yasuhiro Tanabe

  7. Tokyo Women’s Medical University Hospital, Tokyo, Japan

    Masashi Nakao

  8. Tokyo Rosai Hospital, Tokyo, Japan

    Makoto Utsunomiya

  9. St. Luke’s International Hospital, Tokyo, Japan

    Atsushi Mizuno

  10. Tokyo Medical University Ibaraki Medical Center, Ibaraki, Japan

    Michiaki Higashitani

Authors
  1. Atsushi Funatsu
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  2. Hitoshi Anzai
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  3. Kota Komiyama
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  4. Kuniomi Oi
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  5. Hiroshi Araki
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  6. Yasuhiro Tanabe
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  7. Masashi Nakao
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  8. Makoto Utsunomiya
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  9. Atsushi Mizuno
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  10. Michiaki Higashitani
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  11. Shigeru Nakamura
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Corresponding author

Correspondence to Atsushi Funatsu.

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Ethical approval

All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional and/or national research committee and with the 1964 Helsinki Declaration and its later amendments or comparable ethical standards. For this type of study formal consent is not required. The study protocol was reviewed and approved by the institutional review boards and ethics committee of each participating hospital, and posted for eligible patients.

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The authors declare that they have no conflict of interest.

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Funatsu, A., Anzai, H., Komiyama, K. et al. Stent implantation for May–Thurner syndrome with acute deep venous thrombosis: acute and long-term results from the ATOMIC (AcTive stenting for May–Thurner Iliac Compression syndrome) registry. Cardiovasc Interv and Ther 34, 131–138 (2019). https://doi.org/10.1007/s12928-018-0532-y

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  • DOI: https://doi.org/10.1007/s12928-018-0532-y

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