Abstract
“Eco” synthesis has become a reliable, sustainable, and ecological protocol in the field of material science, which has given great attention to synthesizing a wide range of material/nanomaterials, such as nanomaterials, hybrid materials, and bio-inspired metal-metal oxides. Green synthesis is therefore considered an important tool for reducing the destructive effects of traditional nanoparticle syntheses commonly used in laboratory and industry. The aim of the present study was to investigate the effect of carob leaf–synthesis magnetic iron oxide nanoparticles on the oxidative status of the liver, kidney, spleen, and testis of male Wistar rats. The green synthesized nanoparticles were characterized through transmission electron microscopy, dynamic light scattering, and atomic force microscopy. The green-synthesized magnetite nanoparticles had 16 ± 2.4 nm average diameter and were monodispersed. The prepared nanoparticles did not cause oxidative stress damage in the tested organs, and this is mainly due to the strong antioxidant power of the carob leaf extract used in their synthesis. Carob leaf–synthesized nanoparticles prepared in the present study are highly safe which make them suitable to be used in many biological and medical applications.
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The author would like to Acknowledge Prof. Dr. Neveen A Noor, Zoology Department, Faculty of Science, Cairo University, and Miss Esraa M. Ali, Biophysics Department, Faculty of Science, Cairo University, for their help and cooperation.
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Fahmy, H.M. Oxidative Impact of Carob Leaf Extract–Synthesized Iron Oxide Magnetic Nanoparticles on the Kidney, Liver, Testis, and Spleen of Wistar Rats. BioNanoSci. 10, 54–61 (2020). https://doi.org/10.1007/s12668-019-00704-1
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DOI: https://doi.org/10.1007/s12668-019-00704-1