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The Burden of Colorectal Cancer Attributable to Diet Low in Fiber from 1990 to 2019: A Global, Regional and National Analysis

  • Original Research
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The journal of nutrition, health & aging

Abstract

Objectives

The colorectal cancer (CRC) burden is increasingly high. The aim of this study was to investigate temporal and geographical trends in CRC deaths and disability-adjusted life-years (DALYs) attributable to diet low in fiber globally from 1990 to 2019.

Design

Cross-sectional study.

Setting

The study based on the Global Burden of Disease Study (GBD) 2019.

Participants

The population comprised individuals from 204 countries and territories who were diagnosed with CRC attributable to diet low in fiber from 1990 to 2019.

Measurements

Deaths, DALYs, age-standardized mortality rates (ASMR), and age-standardized DALY rates (ASDR) for CRC attributable to diet low in fiber were described, and estimated annual percentage change (EAPC) was further calculated to assess the burden in different regions, countries, sexes, and age groups. Additionally, we explored the association between EAPC and ASMR/ASDR (in 1990) and Human Development Index (HDI, in 2019).

Results

From 1990 to 2019, global ASMR and ASDR for CRC attributable to diet low in fiber decreased slightly, but the corresponding deaths and DALYs increased by 63.37% and 51.36%, respectively. Those burden varied considerably between regions and countries. The burden was higher in high, high-middle and middle SDI regions, especially in Asia and Western Europe, but when HDI > 0.7, an increasingly rapid decline in ASMR and ASDR was revealed. Unexpectedly, many less well-developed countries within the traditionally low deaths and DALYs regions of Africa, Central Latin America, and Middle East showed gradual increases in ASMR and ASDR.

Conclusion

The global burden of CRC attributable to diet low in fiber has decreased over the last 30 years, but remains at a high level. It is essential for decision-makers to take targeted measures for improving population awareness and intake of dietary fiber.

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Acknowledgments

We appreciate the works by the Global Burden of Disease study 2019 collaborators.

Funding

Funding: None.

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Author notes

  1. These authors contributed equally to this work.

Authors and Affiliations

  1. Department of General Surgery, Shanghai Tenth People’s Hospital, Tongji University School of Medicine 301 Yanchang Road, Shanghai, 200072, China

    W. Xie, J. Zuo, W. Yu, Z. Hu, Tingsong Yang & Zhenshun Song

  2. Department of General Surgery, Tongren Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China

    Z. Ma

  3. Department of General Surgery, Shanghai Fourth People’s Hospital, Tongji University School of Medicine, 1279 Sanmen Road, Shanghai, 200072, China

    Zhenshun Song

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Contributions

Author Contributions: Conceptualization, ZS.S and TS.Y; Methodology, WC.X; Software, WC.X, JL,Z and ZL,M; Data Curation, WD.Y and ZY,H; Writing — Original Draft Preparation, WC.X, JL,Z and ZL,M; Writing — Review & Editing, ZS.S, TS.Y, WD.Y and ZY,H; Visualization, WC.X, JL,Z and ZL,M; All authors have read and agreed to the published version of the manuscript.

Corresponding authors

Correspondence to Tingsong Yang or Zhenshun Song.

Ethics declarations

Conflicts of Interest: The authors have no conflicts of interest to declare.

Ethics declarations: The Ethics Committee of the Shanghai Tenth People’s Hospital determined that this study did not require approval since it was using a publicly available database. This study was conducted in compliance with the laws of the China.

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Xie, W., Zuo, J., Ma, Z. et al. The Burden of Colorectal Cancer Attributable to Diet Low in Fiber from 1990 to 2019: A Global, Regional and National Analysis. J Nutr Health Aging 26, 1061–1069 (2022). https://doi.org/10.1007/s12603-022-1865-x

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