Abstract
Objectives
In patients with chronic kidney disease, sarcopenia is associated with dialysis treatment, accelerated protein catabolism, and high energy demand. Thus, this study aimed to assess the association between 25-OH vitamin D concentrations and muscle function in patients undergoing hemodialysis.
Design
A cross-sectional study.
Setting
Performed in a hemodialysis clinic.
Participants
79 adult and elderly patients undergoing hemodialysis.
Measurements
The sample was divided according to the SARC-F definition, being 55 patients allocated in the SARC-F <4 group and 24 in the SARC-F ≥4 group. Normal 25-OH vitamin D concentrations was considered when ≥30 ng/dL.
Results
Vitamin D concentrations and number of patients with low or normal muscle function did not differ between the groups. There was no correlation between SARC-F and 25-OH vitamin D levels (r: −0.09, p=0.42).
Conclusions
25-OH vitamin D has no association with muscle function loss in adults and elderly patients undergoing hemodialysis.
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References
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Acknowledgments
GDP would like to The Brazilian National Council for Scientific and Technological Development (CNPq, Brazil, 312252/2019-6).
Funding
No grant was received for this study.
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Authors and Affiliations
Contributions
A. C B Marini, P. C. B. Lobo and G. D. Pimentel contributed to the design of the research; M. Macedo, B.S. Carneiro, A. C. B. Marini, P. C. B. Lobo contributed to the acquisition and analysis of the data; M. Macedo, B.S. Carneiro, A. C. B. Marini, P. C. B. Lobo and G. D. Pimentel contributed to the interpretation of the data; and M. Macedo, B.S. Carneiro, A. C. B. Marini, P. C. B. Lobo and G. D. Pimentel drafted the manuscript. All authors critically revised the manuscript, agree to be fully accountable for ensuring the integrity and accuracy of the work, and read and approved the final manuscript.
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All authors declare: 1. That this manuscript is not published elsewhere; 2. Any conflicts of interest; 3. All criteria for authorship and acknowledgments were made in the manuscript; 4. Appropriate funding statements in the manuscript; 5. They will inform the journal if any subsequent errors are found in the manuscript.
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Marini, A.C.B., Macedo, M., Carneiro, B.S. et al. 25OH Vitamin D Is No Associated with Muscle Function Loss in Adults and Elderly Patients Undergoing Hemodialysis. J Nutr Health Aging 25, 1096–1098 (2021). https://doi.org/10.1007/s12603-021-1682-7
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DOI: https://doi.org/10.1007/s12603-021-1682-7