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Is Dysphagia in Older Patients with Parkinson’s Disease Associated With Sarcopenia?

  • Original Research
  • Published:
The journal of nutrition, health & aging

Abstract

Background

Parkinson’s Disease (PD) and sarcopenia share a number of common pathways, and they can potentially affect each other.

Objective

We aimed to investigate the relationship between dysphagia and sarcopenia in elderly patients with PD compared to healthy controls.

Methods

This case-control study was conducted on 54 elderly PD patients and age-, sex- and body mass index-matched 54 healthy elder persons. Demographic and disease characteristics such as disease duration, stage of disease and Unified Parkinson’s disease rating scale were recorded. All subjects were assessed by 10- item Eating Assessment Tool, Gugging Swallowing Screen tests and flexible fiberoptic endoscopic evaluation of swallowing (FEES) as well as Mini nutritional test short form. Also, A simplified screening tool for assessing sarcopenia (SARC-F), five times sit-to-stand and gait speed tests as well as lumbar magnetic resonance imaging (MRI) cross-sectional area of psoas and paraspinal muscles were used for evaluation of sarcopenia. Patients were divided as «with normal swallowing» or «with dysphagia» according to the FEES results. Three groups were compared among themselves in terms of evaluation methods.

Results

Sarcopenia evaluation parameters were significantly higher in patient groups compared to the control group. Moreover, muscle measurements evaluated by MRI in patients with dysphagia are lower than both patients with normal swallowing and control group (p value between 0.001 and 0.011).

Conclusions

Patients with PD have lower muscle mass compared to healthy controls, and the situation is more pronounced in dysphagic PD patients.

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Funding

Funding: There is no funding source in this study.

Author information

Authors and Affiliations

  1. University of Health Sciences Turkey, Ankara Diskapi Yildirim Beyazit Training and Research Hospital, Department of Physical Medicine and Rehabilitation, Ankara, Turkey

    Ebru Umay, E. A. Ozturk & I. Gundogdu

  2. Polatli Duatepe City Hospital, Physical Medicine and Rehabilitation Clinic, Ankara, Turkey

    Z. A. Yigman

  3. University of Health Sciences Turkey, Ankara Diskapi Yildirim Beyazit Training and Research Hospital, Department of Neurology, Ankara, Turkey

    B. G. Koçer

  4. University of Health Sciences Turkey, Ankara Diskapi Yildirim Beyazit Education and Research Hospital, Department of Physical Medicine and Rehabilitation, 06170, Altindag, Ankara, Turkey

    Ebru Umay

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  1. Ebru Umay
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  2. Z. A. Yigman
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  3. E. A. Ozturk
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  4. I. Gundogdu
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  5. B. G. Koçer
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Corresponding author

Correspondence to Ebru Umay.

Ethics declarations

Conflict of interest: There is no conflict interest among the authors.

Ethical approval: All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional and/or national research committee and with the 1964 Helsinki declaration and its later amendments or comparable ethical standards. Subjects were informed about the study and their written informed consents were obtained at the beginning of the study.

Informed consent: Informed consent was obtained from all individual participant’s caregivers included in the study.

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Umay, E., Yigman, Z.A., Ozturk, E.A. et al. Is Dysphagia in Older Patients with Parkinson’s Disease Associated With Sarcopenia?. J Nutr Health Aging 25, 742–747 (2021). https://doi.org/10.1007/s12603-021-1618-2

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  • DOI: https://doi.org/10.1007/s12603-021-1618-2

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