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Multidimensional evaluation of endogenous and health factors affecting food preferences, taste and smell perception

  • Published:
The journal of nutrition, health & aging

Abstract

Objective

This study, by taking a holistic approach, investigates the relationships between taste, smell sensitivity and food preference with prognostic (endogenous and health) factors including age, gender, genetic taste markers, body mass, cigarette smoking, and number of drugs used.

Design

Cross sectional study.

Setting

Northern Italy.

Participants

203 healthy subjects (160 women/43 men; mean age: 58.2±19.8 years) were examined.

Measurements

Individual taste sensitivity was determined by saccharose, sodium chloride, acetic acid and caffeine solutions and by 6-n-propylthiouracil (PROP) responsiveness test. Olfactory sensitivity has been assessed by «Sniffin’ Sticks». Four tag Single nucleotide polymorphisms (SNPs) in regions of interest were genotyped. Factor analysis and multivariate regression were performed for scaling food preferences and screening prognostic factors, respectively.

Results

Increasing age is associated with decreased responsiveness to NaCl (P=0.001), sweet solutions (P=0.044), and smell perception (P<0.001). Concerning the food preferences, elderly like the “vegetables” and “fruits” but dislike “spicy” more than younger. Regarding number of drugs taken, there is a significant negative effect on smell perception (P<0.001). In addition, drugs reduce both the “vegetables foods” score (P=0.002) and the “milk-product foods” score (P=0.027). With respect to Body Mass Index (BMI), only a significant effect was shown, on sweet perception (P=0.006). Variation in taste receptor genes can give rise to differential perception of sweet, acid and bitter tastes. No effect of gender and smoking was observed.

Conclusions

Our study suggested that age, genetic markers, BMI and drugs use are the factors which affect taste and smell perception and food preferences.

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Authors and Affiliations

  1. University of Pavia, Department of Brain and Behavioral Sciences, Medical and Genomics Statistics Unit, Pavia, Italy

    D. Guido & M. Grassi

  2. University of Pavia, Department of Public Health, Experimental and Forensic Medicine, Biostatistics and Clinical Epidemiology Unit, Pavia, Italy

    D. Guido

  3. University of Pavia, Department of Public Health, Experimental and Forensic Medicine, Section of Human Nutrition, Endocrinology and Nutrition Unit, Azienda di Servizi alla Persona, Pavia, Italy

    Simone Perna & M. Rondanelli

  4. University of Pisa, Department of Biology, Pisa, Italy

    M. Carrai & R. Barale

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  1. D. Guido
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  2. Simone Perna
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Guido, D., Perna, S., Carrai, M. et al. Multidimensional evaluation of endogenous and health factors affecting food preferences, taste and smell perception. J Nutr Health Aging 20, 971–981 (2016). https://doi.org/10.1007/s12603-016-0703-4

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