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Sarcopenia according to the European Working Group on Sarcopenia in older people (EWGSOP) versus dynapenia as a risk factor for disability in the elderly

  • Published:
The journal of nutrition, health & aging

Abstract

Background

Sarcopenia, defined as low muscle mass (LMM), and dynapenia have been associated with adverse outcomes in elderly.

Objective

Contrast the association of sarcopenia versus dynapenia with incidence of disability.

Design p]A four-year prospective study (2006–2010)

Setting

São Paulo, Brazil.

Participants

478 individuals aged 60 and older from the Saúde, Bem-Estar e Envelhecimento (SABE) study who were non-disabled at baseline.

Measurements

Sarcopenia, measured according to the European Working Group on Sarcopenia in Older People (EWGSOP), includes: LMM assessed by skeletal muscle mass index ≤8.90kg/m2 (men) and ≤6.37kg/m2 (women); low muscle strength (LMS) assessed by handgrip strength <30kg (men) and <20kg (women); and low physical performance (LPP) assessed by gait speed ≤0.8m/s. Diagnosis of sarcopenia required LMM plus LMS or LPP. Dynapenia was defined as handgrip strength <30kg (men) and <20kg (women). Covariates included socio-demographic and behavioral variables, medical conditions, hospitalization, depressive symptoms, cognition, perception of vision, hearing and body mass index.

Outcomes

Disability in mobility or instrumental activities of daily living (IADL) or disability in activities of daily living (ADL) and IADL.

Results

The incidence density of mobility or IADL disability was 43.4/1000 person/year and 22.6/1000 person/year for IADL and ADL disability. There was no significant difference in incidence density according sarcopenia or dynapenia status. After controlling for all covariates, sarcopenia was associated with mobility or IADL disability (relative risk ratio = 2.23, 95%Confidence Interval: 1.03–4.85). Dynapenia was not associated with disability.

Conclusions

Sarcopenia according to the EWGSOP definition can be used in clinical practice as a screening tool for early functional decline (mobility or IADL disability).

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Authors and Affiliations

  1. Department of Epidemiology, School of Public Health, University of São Paulo, São Paulo, Brazil

    Tiago da Silva Alexandre

  2. Department of Physical Therapy, University of Pindamonhangaba, Pindamonhangaba, USA

    Tiago da Silva Alexandre

  3. Department of Medical Surgical Nursing, Nursing School, University of São Paulo, São Paulo, Brazil

    Y. A. De Oliveira Duarte

  4. Department of Social Medicine, University of São Paulo, São Paulo, Brazil

    J. L. Ferreira Santos

  5. Department of Preventive Medicine and Community Health, University of Texas Medical Branch, Galveston, USA

    R. Wong

  6. Department of Epidemiology, School of Public Health, University of São Paulo, São Paulo, Brazil

    M. L. Lebrão

  7. Department of Epidemiology, University of São Paulo, São Paulo, Brazil

    Tiago da Silva Alexandre

Authors
  1. Tiago da Silva Alexandre
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  2. Y. A. De Oliveira Duarte
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  3. J. L. Ferreira Santos
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  4. R. Wong
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  5. M. L. Lebrão
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Correspondence to Tiago da Silva Alexandre.

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da Silva Alexandre, T., De Oliveira Duarte, Y.A., Ferreira Santos, J.L. et al. Sarcopenia according to the European Working Group on Sarcopenia in older people (EWGSOP) versus dynapenia as a risk factor for disability in the elderly. J Nutr Health Aging 18, 547–553 (2014). https://doi.org/10.1007/s12603-014-0465-9

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  • DOI: https://doi.org/10.1007/s12603-014-0465-9

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