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Factors related to withholding life-sustaining treatment in hospitalized elders

  • Factors Related to Withholding Life-Sustaining Treatment in Hospitalized Elders
  • Published:
JNHA - The Journal of Nutrition, Health and Aging

Abstract

Objectives

To look for predictors in the clinical records of orders for “limitation of life sustaining treatment” (LLST) or “do not attempt resuscitation” (DNAR) in hospitalized elders and to assess the relationship between the presence of these orders and the quality of end-of-life (EOL) care.

Design

Retrospective clinical record review.

Setting

Inpatients of an inner city elderly acute care unit (EACU) in Spain.

Participants

Of 103 hospitalized patients who died in the EACU during one year, 90 dying an expected death either from acute or chronic disease were included.

Measurements

Demographic, functional, cognitive, clinical, and end-of-life (EOL) parameters. The influence of identifying closeness to death and the number of LLST suborders on the quality of EOL-management were considered simultaneously using structural equation modelling with LISREL 8.30 software.

Results

LLST and specific DNAR orders were registered in 91.1% and 83.3% of patients, respectively. Failure of acute treatment, discussions with the patient/family, recognizing the presence of common EOL symptoms, and prescribing specific symptomatic treatment were recorded in 88.9%, 93.3%, 94.4%, and 86.7% of patients, respectively. LLST-orders were more likely to be documented if there was severe functional impairment prior to admission (p<0.001), advanced organ disease criteria were met (p=0.006), or closeness to death was acknowledged in writing (p<0.001). The quality of the EOL-management was better in patients for whom there were LLST-orders (p =0.01) and written acknowledgement of closeness to death (p<0.001).

Conclusions

LLST-orders were more likely to be written in an EACU for patients with previous severe impairment, co-morbidity, or advanced disease. Written acknowledgement of closeness to death and LLST-orders were predictors of better EOL-management.

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References

  1. Mathers CD, Loncar D. Updated projections of global mortality and burden of disease, 2002–2030: data sources, methods and results. Geneva: World Health Organization, 2006. Available at www.who.int/healthinfo/statistics/bod_projections 2030_paper.pdf. Accessed 23.8.08

    Google Scholar 

  2. Temkin-Greener H, Mukamel DB. Predicting place of death in the program of allinclusive care for the elderly (PACE): participant versus program characteristics. J Am Geriatr Soc 2002;50(1):125–135.

    Article  PubMed  Google Scholar 

  3. Levy CR, Fish R, Kramer A. Site of death in the hospital versus nursing home of Medicare skilled nursing facility residents admitted under Medicare’s Part A Benefit. J Am Geriatr Soc 2004;52(8):1247–1254.

    Article  PubMed  Google Scholar 

  4. van der Heide A, Delinees L, Faisst K, Nilstum T, Norup M, Paci E et al. End of life decision-making in six European countries: descriptive study. Lancet 2003;362(9381):345–350

    Article  PubMed  Google Scholar 

  5. van Delden JJ, Löfmark R, Deliens L, Bosshard G, Norup M, Cecioni R et al: EURELD Consortium. Do-not-resuscitate orders in six European countries. Crit Care Med 2006;34(6):1837–1838

    Article  Google Scholar 

  6. Chan DK, Ong B, Zhang K, Li R, Liu JG, Iedema R et al. Hospitalization, care plans and not for resuscitation orders in older people in the last year of life. Age Ageing 2003;32(4):445–449.

    Article  PubMed  Google Scholar 

  7. Gleeson K, Wise S. The do not resuscitate order: still too little too late. Arch Intern Med 1990;150(5):1057–1060.

    Article  CAS  PubMed  Google Scholar 

  8. Aarons E, Beeching N. Survey of “do not resuscitate” orders in a district general hospital. BMJ 1991:303(6816):1504–1506

    Article  CAS  PubMed  Google Scholar 

  9. Hamel MB, Lynn J, Zhong Zo, Somogyi-Zalud E. Elderly persons’ last six months of life: findings from The Hospitalized Elderly Longitudinal Project. J Am Geriatr Soc 2000;48(S5):S131–139.

    PubMed  Google Scholar 

  10. Lynn J, De Vries KO, Arkes HR Stevens M, Cohn F, Murphy P et al. Ineffectiveness of the SUPPORT intervention: review of explanations. J Am Geriatr Soc 2000;48(S5):S206–213.

    CAS  PubMed  Google Scholar 

  11. Formiga F, Vivanco V, Cuapio Y, Porta J, Gómez-Batiste X, Pujol R. Dying in hospital from end-stage non-oncologic disease: a decision-making analysis. Med Clin (Barc.) 2003;121(3):95–97.

    Article  Google Scholar 

  12. Formiga F, Vidaller A, Mascaró J, Pujol R. Morir en el hospital por demencia en fase terminal: análisis de la toma de decisiones después de un programa educativo. (Dying in hospital with end-stage dementia: decision-making analysis after an educational program) Rev Esp Geriatr Gerontol 2005;40(1):18–21.

    Article  Google Scholar 

  13. Cantor M, Braddock CH 3rd, Derse A, Edwards DM, Loque GL, Nelson W et al. DNR orders and medical futility. Arch Intern Med 2003;163(22):2689–2694.

    Article  PubMed  Google Scholar 

  14. Meilink M, Van Der Wetering K, Klip H. Discussing and documenting (do not attempt) resuscitation orders in a Dutch hospital: a disappointing reality. Resuscitation 2006:71(3):322–326.

    Article  PubMed  Google Scholar 

  15. Harris D, Davies R. An audit of “do not attempt resuscitation” decisions in two district general hospitals: do current guidelines need changing? Postgrad Med J 2007;83(976):137–140.

    Article  PubMed  Google Scholar 

  16. Flaming, D. Improve care and comfort: use the label “dying”. J Palliat Care 2000;16(2):30–36.

    CAS  PubMed  Google Scholar 

  17. Bailey F, Burgio KL, Woodby LL, Williams BR, Redden DT, Kovac SH et al. Improving processes of hospital care during the last hours of life. Arch Intern Med. 2005;65(5):1722–1727.

    Article  Google Scholar 

  18. Luchins D, Hanraham P, Murphy K. Criteria for enrolling patients in hospice. J Am Geriatr Soc 1997;45:1054–1059.

    CAS  PubMed  Google Scholar 

  19. Stuart B, Kinzbrunner B. Guidelines for determining prognosis in selected non cancer diseases. Hospice J 1996;11:47–63.

    Google Scholar 

  20. Regalado-Doña P, Valero-Ubierna C, González-Montalvo J, Salgado-Alba A. Las escalas de la Cruz Roja veinticinco años después. Estudio de su validez en un servicio de Geriatría. (Red Cross Scales 25 years after. Analysis of their validity in an Elderly Care Department). Rev Esp Geriatr Gerontol 1997;32(2):93–99

    Google Scholar 

  21. Mahoney FI. Barthel DW. Functional evaluation: the Barthel Index. Maryland State Medical J 1965;14:61–65.

    CAS  Google Scholar 

  22. Charlson ME, Pompei P, Ales KL, MacKenzie CR. A new method of classifying prognostic comorbidity in longitudinal studies: development and validation. J Chron Dis 1987;40(5):373–383.

    Article  CAS  PubMed  Google Scholar 

  23. Christakis N, Escarce J. Survival of Medicare patients after enrollment in hospice programs. N Engl J Med 1996;335(3):172–178.

    Article  CAS  PubMed  Google Scholar 

  24. Hoehn M, Yahr M, Parkinsonism: onset, progression and mortality. Neurology 1967;17:427–442.

    CAS  PubMed  Google Scholar 

  25. Jöreskog K, Sörbom, D. L LISREL 8 user’s reference guide. Chicago: Scientific Software International, 1997

    Google Scholar 

  26. Löfmark R, Nilstun T, Cartwright C, Fischer S, van der Heide A, Norup M et al. Physicians’ experiences with end-of-life decision-making: Survey in 6 European countries and Australia. BMC Medicine 2008;6:4.

    PubMed  Google Scholar 

  27. Vila-Santasuana A, Celorrio-Jimenez N, Sanz-Salvador X, Martinez-Montantí J, Díez-Cascón-Menéndez E, Puig-Rosell C. Última semana de vida en un hospital de agudos: revision de 401 pacientes consecutivos. (The final week of life in an acute care hospital: review of 401 consecutive patients) In press, Rev Esp Geriatr Gerontol 2008;43(5):284–289.

    Article  PubMed  Google Scholar 

  28. Hesse KA. Terminal care of the very old: changes in the way we die. Arch Intern Med 1995;155(14):1513–1518.

    Article  CAS  PubMed  Google Scholar 

  29. Tschann J, Kaufman S, Micco G. Family involvement in end-of-life hospital care. J Am Geriatr Soc 2003;51(6):835–840.

    Article  PubMed  Google Scholar 

  30. Lamberg JL, Person CJ, Kiely DK, Mitchell SL. Decisions to hospitalize nursing home residents dying with advanced dementia. J Am Geriatr Soc 2005;53(8):1396–1401.

    Article  PubMed  Google Scholar 

  31. Miccinesi G, Fischer S, Paci E, Onwuteaka-Philipsen BD, Cartwright C, Van Der Heide A et al. Physicians’ attitudes towards end-of-life decisions: a comparison between seven countries. Soc Sci Med 2005;60(9):1961–1974.

    Article  PubMed  Google Scholar 

  32. Hakim RB, Teno JM, Harrell FE Jr, Knauss WA, Wengwer N, Phillips RS et al. Factors associated with do not resuscitate orders: patients’ preferences, prognoses, and physicians’ judgements. SUPPORT Investigators. Ann Intern Med 1996;125(4):284–293.

    CAS  PubMed  Google Scholar 

  33. Lorenz KA, Rosenfeld K, Wenger N. Quality indicators for palliative and end-of-life-care in vulnerable elders. J Am Geriatr Soc 2007;55(S2):S318–326

    Article  PubMed  Google Scholar 

  34. Rietjens JA, Van Der Heide A, Onwuteaka-Philipsen BD, Van Der Maas PJ, Van Der Wal G. Preferences of the Dutch public for a good death and associations with attitudes towards end-of-life decision making. Palliat Med 2006;20(7):685–692

    Article  PubMed  Google Scholar 

  35. Kessel H, Pageo M, Marín N. Preferencias respecto a la información médica y directrices sobre soporte vital en una población geriátrica española. (Preferences regarding medical information and orders on life sustaining treatment in a geriatric Spanish population) Rev Esp Geriatr Gerontol 1994;29(2):79–83.

    Google Scholar 

  36. Nicolasora, N, Pannala R, Mountantonakis S, Shanmugam B, De Girolamo A, Amoateng-Adjepong Y et al. If asked, hospitalized patients will choose whether to receive life-sustaining therapies. J Hosp Med 2007;1(3):161–167.

    Article  Google Scholar 

  37. Goodlin SJ, Winzelberg GS, Teno J, Whedon M, Lynn J. Death in hospital. Arch Intern Med 1998,158:1570–1572.

    Article  CAS  PubMed  Google Scholar 

  38. Veerbeek L, Van Zuylen L, Swart SJ, Jongeneel G, Van Der Maas PJ, Van Der Heide A. Does recognition of the dying phase have an effect on the use of medical interventions? J Palliat Care 2008;24(2):94–99.

    PubMed  Google Scholar 

  39. Teno J. Measuring end-of-life care outcomes retrospectively. J Palliat Med. 2005;8(S1):S42–49.

    PubMed  Google Scholar 

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Correspondence to A. Esteve or C. Jimenez.

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Esteve, A., Jimenez, C., Perez, R. et al. Factors related to withholding life-sustaining treatment in hospitalized elders. J Nutr Health Aging 13, 644–650 (2009). https://doi.org/10.1007/s12603-009-0176-9

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  • DOI: https://doi.org/10.1007/s12603-009-0176-9

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