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Polydopamine modified CuS@HKUST for rapid sterilization through enhanced photothermal property and photocatalytic ability

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Abstract

Because of the impressive evolution of the drug-resistant bacteria, the development of efficient, antibiotic-free agent is in great urgency. Herein, an efficient antibacterial agent, CuS@HKUST-polydopamine (PDA), was exquisitely designed, where the Cu-based metal-organic framework (MOF)—HKUST nanoparticles served as the porous frame, and the CuS was synthesized within the structure of the MOF through the process of in situ sulfuration, followed with polydopamine (PDA) covering the nanoparticles. The structure of the HKUST preventing the aggregation of the CuS nanoparticles, which improved their photothermal and photocatalytic properties. After covering with PDA, the nanoparticles’ abilities to produce heat and free radicals were further enhanced. This was because that the PDA itself could transform light into heat, which not only benefited the photothermal property, but also improved the photocatalytic property of the nanoparticles by accelerating the charge mobility. Moreover, the PDA could also transfer the photo-induced electrons fast and thus prevented the recombination of the photo-generated electron–hole pairs, which resulted in the enhanced ability to produce free radicals. As a result, under light irradiation, the antibacterial efficiency of the CuS@HKUST-PDA against Staphylococcus aureus (S. aureus) and Escherichia coli (E. coli) could reach 99.77% and 99.57%. Hence, the synthesized CuS@HKUST-PDA can be promising for anti-infection and sterilization application without using antibiotics.

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摘要

由于耐药菌的飞速进化, 研发有效的, 非抗生素类的抗菌剂迫在眉睫。本文设计了一种高效的抗菌剂——CuS@HKUST-聚多巴胺(PDA)。这种复合材料使用铜基金属-有机框架结构 (MOF)——HKUST作为多孔框架, 通过原位硫化的方法在HKUST颗粒中原位生成CuS纳米颗粒, 并使用聚多巴胺 (PDA) 包覆纳米颗粒。HKUST的多孔结构可以有效防止CuS纳米颗粒之间的团聚, 并避免由此导致的光热转换效率降低。当纳米颗粒表面包裹一层PDA后, 复合纳米颗粒在光照下产生热量和自由基的能力均会明显增强。这主要是由以下几方面原因造成的: 首先, PDA自身可以将光转换为热量, 提高复合材料的光热转换能力; 同时高热也可以提高电子的流动性, 进而增强复合纳米材料的光动力性能。此外, PDA可以快速转移光致电子,阻碍电子-空穴的复合, 进一步提高纳米颗粒在光照下产生自由基的能力。在光照下, CuS@HKUST-PDA对金黄色葡萄球菌和大肠杆菌的抗菌率分别可以达到99.77%和99.57%。因此, CuS@HKUST-PDA纳米颗粒作为非抗生素类抗菌剂在抗感染和食品杀菌等方面有较大的潜力。

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Acknowledgements

This work was financially supported by Jilin Provincial Science and Technology Project (No. YDZJ202101ZYTS054), the National Science Fund for Distinguished Young Scholars (No. 51925104) and the National Natural Science Foundation of China (No. 51871162).

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Authors and Affiliations

  1. College of Materials Science and Engineering, Jilin Institute of Chemical Technology, Jilin, 132022, China

    Dong-Lin Han

  2. School of Materials Science and Engineering, the Key Laboratory of Advanced Ceramics and Machining Technology by the Ministry of Education of China, Tianjin University, Tianjin, 300072, China

    Peng-Li Yu, Ying-De Xu & Shui-Lin Wu

  3. Ministry-of-Education Key Laboratory for the Green Preparation and Application of Functional Materials, Hubei Key Laboratory of Polymer Materials, School of Materials Science and Engineering, Hubei University, Wuhan, 430062, China

    Xiang-Mei Liu

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  1. Dong-Lin Han
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Han, DL., Yu, PL., Liu, XM. et al. Polydopamine modified CuS@HKUST for rapid sterilization through enhanced photothermal property and photocatalytic ability. Rare Met. 41, 663–672 (2022). https://doi.org/10.1007/s12598-021-01786-1

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  • DOI: https://doi.org/10.1007/s12598-021-01786-1

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