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Microstructure, fracture behavior, in vitro corrosion resistance, and cytotoxicity of Zn–Mg/Mg–Zn–HAp laminated composites produced by spark plasma sintering

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Abstract

Ideal biodegradable materials exhibit suitable degradation rates and sufficient mechanical properties for their specific application. With these parameters in mind, Zn–Mg/Mg–Zn–hydroxyapatite (HAp) laminated composites were designed and fabricated by spark plasma sintering. This paper describes the structure, mechanical properties, in vitro corrosion resistance, and cytotoxicity of the Zn–Mg/Mg–Zn–HAp laminated composites. The compressive strength and elastic moduli of the laminated composites matched that of cortical bone and could effectively reduce the stress shielding effect as an implant with good biomechanical compatibility. Analysis of the fracture path and morphology after fracture toughness tests indicated that the Zn–Mg/Mg–Zn–HAp laminated composites exhibited significant capacity to prevent crack propagation, improving the fracture toughness. In vitro degradation experiments showed that the design of the laminated structure can provide a gradient degradation rate for the material. Furthermore, the laminated composites exhibited excellent biocompatibility and are promising candidates for orthopedic implants.

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Acknowledgements

This study was financially supported by the National Natural Science Foundation of China (No. 51305292) and the Natural Science Foundation of Shanxi Province (No. 201801D121089).

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Authors and Affiliations

  1. School of Materials Science and Engineering, Taiyuan University of Technology, Taiyuan, 030024, China

    Ya-Kai Zhang, Ze-Qin Cui, Dian-Qing Gong, Wen-Xian Wang & Wei-Li Cheng

  2. Key Laboratory of Interface Science and Engineering in Advanced Materials, Taiyuan University of Technology, Taiyuan, 030024, China

    Ya-Kai Zhang, Ze-Qin Cui & Wen-Xian Wang

  3. Shanxi Province Boiler and Pressure Vessel Supervision and Inspection Institute, Taiyuan, 030024, China

    Ya-Kai Zhang

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  1. Ya-Kai Zhang
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  2. Ze-Qin Cui
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Correspondence to Ze-Qin Cui.

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Zhang, YK., Cui, ZQ., Gong, DQ. et al. Microstructure, fracture behavior, in vitro corrosion resistance, and cytotoxicity of Zn–Mg/Mg–Zn–HAp laminated composites produced by spark plasma sintering. Rare Met. 40, 939–951 (2021). https://doi.org/10.1007/s12598-019-01361-9

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