Skip to main content
Log in

Systematic approach to long standing pleomorphic adenoma of the upper lip

  • case study
  • Published:
international journal of stomatology & occlusion medicine

Abstract

Pleomorphic adenoma is a benign tumor commonly involving the salivary glands and mainly the parotid gland. It affects the minor salivary glands with the palate being the most common site of occurrence. The involvement of the upper lip is considered rare with very few reports in the literature. Clinically it is a painless, non-erythematous, firm and slowly growing tumor. Microscopically it has a biphasic microscopic appearance with mixed epithelial and stromal components. Although it is benign the rate of malignant transformation is reported as being up to 4 % in long standing cases. The incidence of this tumor has been reported in various gender, ethnic and geographic groups. With the recent reports of the increase in the variations of location and the biological nature of the tumor the need for extensive research is more demanding. This case report presents a systematic approach to long standing pleomorphic adenoma affecting the upper lip.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Fig. 1
Fig. 2
Fig. 3
Fig. 4

Similar content being viewed by others

References

  1. Debnath SC, Adhyapok AK. Pleomorphic adenoma (benign mixed tumour) of the minor salivary glands of the upper lip. J Maxillofac Oral Surg. 2010;9(2):205–8.

    Article  PubMed Central  PubMed  Google Scholar 

  2. Shrestha A, Reddy NS, Ganguly SN. Pleomorphic adenoma of the upper lip: a case report. Nepal Med Coll J. 2011;6(1):51–3.

    Google Scholar 

  3. Dyalram D, Huebner T, Papadimitriou JC, Lubek J. Carcinoma ex pleomorphic adenoma of the upper lip. Int J Oral Maxillofac Surg. 2012;41:364–7.

    Article  CAS  PubMed  Google Scholar 

  4. Ali I, Gupta AK, Singh S. Pleomorphic adenoma of the upper lip. Natl J Maxillofac Surg. 2011;2:219–21.

    Article  PubMed Central  PubMed  Google Scholar 

  5. Gomes CC, Diniz MG, Orsine LA, Duarte AP, Fonseca-Silva T. Assessment of TP53 mutations in benign and malignant salivary gland neoplasms. PLoS One. 2012;7:e41261.

    Article  Google Scholar 

  6. Kataria SP, Talwar P, Sethi D, Garg M. Pleomorphic adenoma of the upper lip. J Cutan Aesthet Surg. 2011;3:217–9.

    Google Scholar 

  7. Lotufo MA, Júnior CA, Mattos JP, França CM. Pleomorphic adenoma of the upper lip in a child. J Oral Sci. 2008;50:225–8.

    Article  PubMed  Google Scholar 

  8. Sengul I, Sengul D, Aribas D. Pleomorphic adenoma of the lower lip: a rare site of location. N Am J Med Sci. 2011;3:299–301.

    Article  PubMed Central  PubMed  Google Scholar 

  9. Asuquo ME, Otei OO, Ekpo R, Abang I, Adams U, Bassey EE, Ebughe G. Salivary gland tumour of the lip: report of two cases and literature review. Cent Afr J Med. 2009;55:43–6.

    CAS  PubMed  Google Scholar 

  10. Hamakawa H, Takarada M, Ito C, Tanioka H. Bone-forming pleomorphic adenoma of the upper lip: report of a case. J Oral Maxillofac Surg. 1997;55:1471–5.

    Article  CAS  PubMed  Google Scholar 

  11. Pons Vicente O, Almendros Marqués N, Berini Aytés L, Gay Escoda C. Minor salivary gland tumors: a clinicopathological study of 18 cases. Med Oral Patol Oral Cir Bucal. 2008;13:582–8.

    Google Scholar 

  12. KüçüK U, Tan S. Pleomorphic adenoma of the upper lip. Turk Patoloji Derg. 2011;27:73–6.

    PubMed  Google Scholar 

  13. Kuo YL, Tu TY, Chang CF, Li WY, Chang SY, Shiao AS, Chu PY, Chan KT, Tai SK, Wang YF, Kao SC, Kao SY, Lo WL, Wu CH, Shu WH, Ma S, Wang TH. Extra-major salivary gland pleomorphic adenoma of the head and neck: a 10-year experience and review of the literature. Eur Arch Otorhinolaryngol. 2011;268:1035–40.

    Article  PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Irfan Mohammed MDS. MOMS RCPSG.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Mohammed, I., Saghali, A., Ramasamy, S. et al. Systematic approach to long standing pleomorphic adenoma of the upper lip. J. Stomat. Occ. Med. 7, 53–56 (2014). https://doi.org/10.1007/s12548-013-0102-y

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s12548-013-0102-y

Keywords

Navigation