Skip to main content
Log in

Pleomorphic Adenoma (Benign Mixed Tumour) of the Minor Salivary Glands of the Upper Lip

  • Case Report
  • Published:
Journal of Maxillofacial and Oral Surgery Aims and scope Submit manuscript

Abstract

Pleomorphic adenoma is the benign tumor of salivary glands, which originates from the myoepithelial cells and intercalated duct cells. This tumor is more common in major salivary glands. This case report describes a rare and unusual lesion in a 55-year-old female, which was diagnosed as pleomorphic adenoma of the minor salivary glands in the upper lip. The tumor was a circumscribed, submucosal nodule, about 2.0 cm in diameter and was characterized by slow growth and rubbery consistency. Complete excision was performed and the histopathological analysis showed an epithelial salivary gland tumor with islands of plasmacytoid cells, duct like structures, in a variable stroma with chondroid, fibrous and myxoid appearance. No recurrence was observed 1 year after the surgery.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Fig. 1
Fig. 2
Fig. 3
Fig. 4
Fig. 5
Fig. 6
Fig. 7

References

  1. Luna MA, Batsakis JG, el-Naggar AK (1991) Salivary gland tumours in children. Ann Otol Rhinol Laryngol 100(10):869–871

    CAS  PubMed  Google Scholar 

  2. Bradley P, McClelland L, Mehta D (2007) Paediatric salivary gland epithelial neoplasms. ORL J Otorhinolaryngol Relat Spec 69(3):137–145

    PubMed  Google Scholar 

  3. Shaaban H, Bruce J, Davenport PJ (2001) Recurrent pleomorphic adenoma of the palate in a child. Br J Plast Surg 54(3):245–247

    Article  CAS  PubMed  Google Scholar 

  4. Spiro RH (1986) Salivary neoplasms: overview of a 35-year experience with 2,807 patients. Head Neck Surg 8(3):177–184

    Article  CAS  PubMed  Google Scholar 

  5. Waldron CA, el-Mofty SK, Gnepp DR (1988) Tumours of the intraoral minor salivary glands: a demographic and histologic study of 426 cases. Oral Surg Oral Med Oral Pathol 66(3):323–333

    Article  CAS  PubMed  Google Scholar 

  6. Eveson JW, Cawson RA (1985) Tumours of the minor (oropharyngeal) salivary glands: a demographic study of 336 cases. J Oral Pathol 14(6):500–509

    Article  CAS  PubMed  Google Scholar 

  7. Cohen MA (1986) Pleomorphic adenoma of the cheek. Int J Oral Maxillofac Surg 15(6):777–779

    Article  CAS  PubMed  Google Scholar 

  8. Bailey BJ (2001) Head and neck surgery. In: Otolaryngology, chap 107, 3rd edn. Lippincott Williams and wilkins, Philadelphia

  9. Ballenger JJ (2003) Head and neck surgery. In: Otolaryngology, vol 2, chaps 50, 54, 62, 16th edn. BC Decker Inc., Spain

  10. Forty MJ, Wake MJ (2000) Pleomorphic salivary adenoma in an adolescent. Br Dent J 188(10):545–546

    Article  CAS  PubMed  Google Scholar 

  11. Berjis N, Haji Malian M (2006) Pleomorphic adenoma presented as a subglotic mass. 7. http://semj.sums.ac.ir.

  12. Jorge J, Pires FR, Alves FA, Perez DE, Kowalski LP, Lopes MA, Almeila OP (2002) Juvenile intraoral pleomorphic adenoma: report of five cases and review of the literature. Int J Oral Maxillofac Surg 31(3):273–275

    Article  CAS  PubMed  Google Scholar 

  13. Daniels JS, Ali I, Al Bakri IM, Sumangala B (2007) Pleomorphic adenoma of the palate in children and adolescents: a report of 2 cases and review of the literature. J Oral Maxillofac Surg 65(3):541–549

    Article  PubMed  Google Scholar 

  14. McGregor AD, Burgoyne M, Tan KC (1988) Recurrent pleomorphic salivary adenoma—the relevance of age at first presentation. Br J Plast Surg 41(2):177–181

    Article  CAS  PubMed  Google Scholar 

  15. Ellies M, Schaffranietz F, Arglebe C, Laskawi R (2006) Tumours of the salivary glands in childhood and adolescence. J Oral Maxillofac Surg 64(7):1049–1058

    Article  PubMed  Google Scholar 

  16. Har-El G, Zirkin HY, Tovi F, Sidi J (1985) Congenital pleomorphic adenoma of the nasopharynx (report of a case). J Laryngol Otol 99(12):1281–1287

    Article  CAS  PubMed  Google Scholar 

  17. Dehner LP, Valbuena L, Perez-Atayde A, Reddick RL, Askin FB, Rosai J (1994) Salivary gland anlage tumour (“congenital pleomorphic adenoma”). A clinicopathologic, immunohistochemical and ultrastructural study of nine cases. Am J Surg Pathol 18(1):25–36

    Article  CAS  PubMed  Google Scholar 

  18. Herrmann BW, Dehner LP, Lieu JE (2005) Congenital salivary gland anlage tumour: a case series and review of the literature. Int J Pediatr Otorhinolaryngol 69(2):149–156

    Article  PubMed  Google Scholar 

  19. Cohen EG, Yoder M, Thomas RM, Salerno D, Isaacson G (2003) Congenital salivary gland anlage tumour of the nasopharynx. Pediatrics 112(1 Pt 1):e66–69

    Article  PubMed  Google Scholar 

  20. Furuse C, Sousa SO, Nunes FD, Magalhães MH, Araújo VC (2005) Myoepithelial cell markers in salivary gland neoplasms. Int J Surg Pathol 13(1):57–65

    Article  CAS  PubMed  Google Scholar 

Download references

Acknowledgement

I wish to thank Dr Pascal X. Pinto, MDS, FDSRCS, Professor, Department of Oral and Maxillofacial Surgery, KIDS Belgaum, for his support and guidance in preparing the manuscript.

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Subhas Chandra Debnath.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Debnath, S.C., Adhyapok, A.K. Pleomorphic Adenoma (Benign Mixed Tumour) of the Minor Salivary Glands of the Upper Lip. J. Maxillofac. Oral Surg. 9, 205–208 (2010). https://doi.org/10.1007/s12663-010-0052-5

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s12663-010-0052-5

Keywords

Navigation