Samenvatting
Obsessief-compulsieve stoornissen (OCD’s), zoals beschreven in ons artikel in het allereerste nummer van Neuropraxis in 1997, staan nog steeds in het middelpunt van de belangstelling. In de laatste twee decennia is er veel onderzoek gedaan naar een scala van aspecten van de OCD; we weten veel meer over betrokken hersenmechanismen, farmacologische en psychologische behandelingen, risicofactoren en erfelijkheid dan twee decennia geleden, maar moeten helaas concluderen dat we nog weinig begrijpen van oorzaken van OCD’s en nog heel ver weg zijn van ‘genezen’. Twintig jaar is toch een relatief korte tijdspanne, ondanks de hoge vlucht die kennis en technologische benaderingen in deze periode hebben genomen binnen de neuro- en gedragswetenschappen.
Literatuur
Olivier B, Oorschot R van. Dwang en Hersenen. Neuropraxis. 1997;1:16–22.
Murphy DL, Timpano KR, Wheaton MG, Greenberg BD, Miguel EC. Obsessive-compulsive disorder and its related disorders: a reappraisal of obsessive-compulsive spectrum concepts. Dialogues Clin Neurosci. 2010;12:131–48.
Pope HG Jr, Khalsa JH, Bhasin S. Body image disorders and abuse of anabolic-androgenic steroids among men. JAMA. 2017;317:23–4.
British Association for Psychopharmacology, Baldwin DS, Anderson IM, Nutt DJ, Bandelow B, Bond A, Davidson JR, et al. Evidence-based guidelines for the pharmacological treatment of anxiety disorders: recommendations from the British Association for Psychopharmacology. J Psychopharmacol (Oxford). 2005;19(6):567–96.
Abudy A, Juven-Wetzler A, Zohar J. Pharmacological management of treatment-resistant obsessive-compulsive disorder. CNS Drugs. 2011;25:585–96.
Rapaport MH, Clary C, Fayyad R, Endicott J. Quality-of-life impairment in depressive and anxiety disorders. Am J Psychiatry. 2005;162:1171–8.
Milad MR, Rauch SL. Obsessive-compulsive disorder: beyond segregated cortico-striatal pathways. Trends Cogn Sci (Regul Ed). 2012;16:43–51.
Rauch SL, Shin LM, Dougherty DD, Alpert NM, Fischman AJ, Jenike MA. Predictors of fluvoxamine response in contamination-related obsessive compulsive disorder: a PET symptom provocation study. Neuropsychopharmacology. 2002;27:782–91.
Ameringen M van, Simpson W, Patterson B, Dell’Osso B, Fineberg N, Hollander E, et al. Pharmacological treatment strategies in obsessive compulsive disorder: a cross-sectional view in nine international OCD centers. J Psychopharmacol (Oxford). 2014;28:596–602.
Quirk GJ, Milad MR. Neuroscience: editing out fear. Nature. 2010;463:36–7.
Kindt M, Soeter M, Vervliet B. Beyond extinction: erasing human fear responses and preventing the return of fear. Nat Neurosci. 2009;12:256–8.
Pallanti S, Marras A, Salerno L, Makris N, Hollander E. Better than treated as usual: transcranial magnetic stimulation augmentation in selective serotonin reuptake inhibitor-refractory obsessive-compulsive disorder, mini-review and pilot open-label trial. J Psychopharmacol (Oxford). 2016;30:568–78.
Trevizol AP, Shiozawa P, Cook IA, Sato IA, Kaku CB, Guimarães FB. Transcranial magnetic stimulation for obsessive-compulsive disorder: an updated systematic review and meta-analysis. J ECT. 2016;32:262–6.
Wilhelm S, Buhlmann U, Tolin DF, Meunier SA, Pearlson GD, Reese HE, et al. Augmentation of behavior therapy with D‑cycloserine for obsessive-compulsive disorder. Am J Psychiatry. 2008;165:335–41.
Sulkowski ML, Geller DA, Lewin AB, Murphy TK, Mittelman A, Brown A, et al. The future of D‑cycloserine and other cognitive modifiers in obsessive-compulsive and related disorders. Curr Psychiatry Rev. 2014;10:317–24.
Bais MN, Figee M, Schuurman RS, Denys D. Diepe hersenstimulatie bij obsessieve-compulsieve stoornis: 10 jaar ervaring in het AMC. Neuropraxis. 2015;19:80–4.
Fayad SM, Guzick AG, Reid AM, Mason DM, Bertone A, Foote KD, et al. Six-nine year follow-up of deep brain stimulation for obsessive-compulsive disorder. PLOS ONE. 2016;11(12):e0167875. doi:10.1371/journal.pone.0167875.
Pauls DL. The genetics of obsessive compulsive disorder: a review of the evidence. Am J Med Genet C Semin Med Genet. 2008;148 C:133–9.
Pauls DL, Abramovitch A, Rauch SL, Geller DA. Obsessive-compulsive disorder: an integrative genetic and neurobiological perspective. Nat Rev Neurosci. 2014;15:410–24.
Szechtman H, Ahmari SE, Beninger RJ, Eilam D, Harvey BH, Edemann-Callesen H, et al. Obsessive-compulsive disorder: insights from animal models. Neurosci Biobehav Rev. 2016; doi:10.1016/j.neubiorev.2016.04.019.
Author information
Authors and Affiliations
Corresponding author
Rights and permissions
About this article
Cite this article
Olivier, B. 20 jaar Neuropraxis: nieuwe ontwikkelingen in ‘dwang en hersenen’. Neuropraxis 21, 22–27 (2017). https://doi.org/10.1007/s12474-017-0151-x
Published:
Issue Date:
DOI: https://doi.org/10.1007/s12474-017-0151-x