Abstract
Recent literature indicates that torsion of the left ventricle (LV) is a promising predictor for response to cardiac resynchronisation therapy (CRT). Among patients with severe heart failure, 45 to 75% of patients show rigid body rotation, where the base and apex rotate in the same direction, instead of normal, opposite rotation. The occurrence of this phenomenon seems to be a good indicator for response to CRT. From this review, it can be concluded that LV torsion might be a welcome addition to current selection criteria.
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Cleland JGF, Daubert JC, Erdmann E, et al. The effect of cardiac resynchronization therapy on morbidity and mortality in heart failure. N Engl J Med. 2005;352:1539–49.
Bleeker GB, Bax JJ, Fung JWH, et al. Clinical versus echocardiographic parameters to assess response to cardiac resynchronization therapy. Am J Cardiol. 2006;97:260–3.
Strickberger SA, Conti J, Daoud EG, et al. Patient selection for cardiac resynchronization therapy. Circ. 2005;111:2760–7.
Chung ES, Leon AR, Tavazzi L, et al. Results of the predictors of response to CRT (PROSPECT) trial. Circ. 2008;117:2608–16.
Rüssel IK, Zwanenburg JJM, Germans T, et al. Mechanical dyssynchrony or myocardial shortening as MRI predictor of response to biventricular pacing? J Magn Res Imaging. 2007;26:1452–60.
Carasso S, Rakowski H, Witte KK, et al. Left Ventricular strain patterns in dilated cardiomyopathy predict response to cardiac resynchronization therapy: timing is not everything. J Am Soc Echocardiogr. 2009;22:242–50.
Helm RH, Leclercq C, Faris OP, et al. Cardiac dyssynchrony analysis using circumferential versus longitudinal strain: implications for assessing cardiac resynchronization. Circ. 2005;111:2760–7.
Bilchick KC, Dimaano V, Wu KC, et al. Cardiac magnetic resonance assessment of dyssynchrony and myocardial scar predicts function class improvement following cardiac resynchronization therapy. JACC Cardiovasc Imaging. 2008;1:561–8.
Lorenz CH, Pastorek JS, Bundy JM. Delineation of normal human left ventricular twist throughout systole by tagged magnetic resonance imaging. J Cardiovasc Magn Reson. 2000;2:97–108.
Arts T, Reneman RS, Veenstra PC. A model of the mechanics of the left ventricle. Ann Biomed Eng. 1979;7:299–318.
Notomi Y, Popovic ZB, Yamada H, et al. Ventricular untwisting: a temporal link between left ventricular relaxation and suction. Am J Physiol Heart Circ Physiol. 2008;294:H505–13.
Axel L, Dougherty L. MR imaging of motion with spatial modulation of magnetization. Radiology. 1989;171:841–5.
Helle-Valle T, Crosby J, Edvardsen T, et al. New noninvasive method for assessment of left ventricular rotation: speckle tracking echocardiography. Circ. 2005;112:3149–456.
Rüssel IK, Götte MJW, Bronzwaer JG, et al. Left ventricular torsion: an expanding role in the analysis of myocardial function. JACC Cardiovasc Imaging. 2009;2:648–55.
Hansen DE, Daughters GT, Alderman EL, et al. Effect of acute cardiac allograft rejection on left ventricular systolic torsion and diastolic recoil measured by intramyocardial markers. Circ. 1987;76:988–1008.
Young AA, Dokos S, Powell KA, et al. Regional heterogeneity of function in nonischemic dilated cardiomyopathy. Cardiovasc Res. 2001;49:308–18.
Nagel E, Stuber M, Lakatos M, et al. Cardiac rotation and relaxation after anterolateral myocardial infarction. Coron Artery Dis. 2000;11:261–7.
Setser RM, Kasper JM, Lieber ML, et al. Persistent abnormal left ventricular systolic torsion in dilated cardiomyopathy after partial left ventriculectomy. J Thorac Cardiovasc Surg. 2003;126:48–55.
Kanzaki H, Nakatani S, Yamada N, et al. Impaired systolic torsion in dilated cardiomyopathy: reversal of apical rotation at mid-systole characterized with magnetic resonance tagging method. Basic Res Cardiol. 2006;101:465–70.
Popescu BA, Beladan CC, Calin A, et al. Left ventricular remodeling and torsional dynamics in dilated cardiomyopathy: reversed apical rotation as a marker of disease severity. Eur J Heart Fail. 2009;11:945–51.
Van Dalen BM, Caliskan K, Soliman OII, et al. Left ventricular solid body rotation in non-compaction cardiomyopathy: a potential new objective and quantitative functional diagnostic criterion? Eur J Heart Fail. 2008;10:1088–93.
Sade LE, Demir O, Atar I, et al. Effect of mechanical dyssynchrony and cardiac resynchronization therapy on left ventricular rotational mechanics. Am J Cardiol. 2008;101:1163–9.
Rüssel IK, Götte MJW, De Roest GJ, et al. Loss of opposite left ventricular basal and apical rotation predicts acute response to cardiac resynchronization therapy and is associated with long-term reversed remodeling. J Card Fail. 2009;15:717–25.
Bertini M, Marsan A, Delgado V, et al. Effects of cardiac resynchronization therapy on left ventricular twist. J Am Coll Cardiol. 2009;54:1317–25.
Zhang Q, Fung JW, Yip GW, et al. Improvement of left ventricular myocardial short-axis, but not long-axis function or torsion after cardiac resynchronization therapy: an assessment by two-dimensional speckle tracking. Heart. 2008;94:1464–71.
Ashikaga H, Leclercq C, Wang J, Kass DA, McVeigh ER. Hemodynamic improvement in cardiac resynchronization does not require improvement in left ventricular rotation mechanics: three-dimensional tagged MRI analysis. Circ Cardiovasc Imaging. 2010, May 17 (epub ahead of print).
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Rüssel, I.K., Götte, M.J.W. New insights in LV torsion for the selection of cardiac resynchronisation therapy candidates. Neth Heart J 19, 386–391 (2011). https://doi.org/10.1007/s12471-011-0136-y
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DOI: https://doi.org/10.1007/s12471-011-0136-y